red blood cells

Ischaemic endothelial necroptosis induces haemolysis and COVID-19 angiopathy Wu, Mike C. L.; Italiano, Ethan; Jarvis-Child, Rocko; Alwis, Imala; Smythe, Rhyll; Albornoz, Eduardo A.; Noonan, Jonathan; Portelli, Marie; Baptista, Marissa; Maclean, Jessica; Noori, Pashtana; Yang, Jinglu; Lee, John...

Prolonged alterations in red blood cell rheology following mild SARS-CoV-2 infection: Implications for microvascular health Pazara; Tudorache; Dusa; Bjørklund; Dadar; Doşa; Chirumbolo; Cambrea The COVID-19 pandemic has prompted widespread investigation into its systemic effects, focusing on the...

Cell membranes sustain phospholipid imbalance via cholesterol asymmetry Milka Doktorova; Jessica L. Symons; Xiaoxuan Zhang; Hong-Yin Wang; Jan Schlegel; Joseph H. Lorent; Frederick A. Heberle; Erdinc Sezgin; Edward Lyman; Kandice R. Levental; Ilya Levental Membranes are molecular interfaces...

Actively Protective Combinatorial Analysis: a Scalable Novel Method for Detecting Variants that Contribute to Reduced Disease Prevalence in High-Risk Individuals Jason Sardell; Sayoni Das; Krystyna Taylor; Colin Stubberfield; Andy Malinowski; Mark Strivens; Steve Gardner We present a novel...

Reduction of hemagglutination induced by a SARS-CoV-2 spike protein fragment using an amyloid-binding benzothiazole amphiphile Li, Meihan; Castro Lingl, Sascha; Yang, Jerry COVID-19 infection is associated with a variety of vascular occlusive morbidities. However, a comprehensive understanding...

Persistent complement dysregulation with signs of thromboinflammation in active Long Covid Open access: https://www.science.org/doi/10.1126/science.adg7942 Editor’s summary Some individuals can endure persistent, debilitating symptoms for many months after an initial severe acute respiratory...

COVID-19 disease, caused by the severe acute respiratory syndrome virus 2 (SARS-CoV-2), induces a broad spectrum of clinical symptoms ranging from asymptomatic cases to fatal outcomes. About 10–35% of all COVID-19 patients, even those with mild COVID-19 symptoms, continue to show symptoms...

Abstract Oxidative stress is one of the key factors that leads to red blood cells (RBCs) aging, and impairs their biomechanics and oxygen delivery. It occurs during numerous pathological processes and causes anaemia, one of the most frequent side effects of cancer chemotherapy. Here, we used...

In an exploratory trial treating “long COVID” with the CCR5-binding antibody leronlimab, we observed significantly increased blood cell surface CCR5 in treated symptomatic responders but not in nonresponders or placebo-treated participants. These findings suggest an unexpected mechanism of...

Microplastics destabilize lipid membranes by mechanical stretching Jean-Baptiste Fleury and Vladimir A. Baulin Significance The effects of plastic pollution on living organisms is a highly debated subject. There is no direct evidence of high toxicity of microplastic abundantly present in the...

Highlights • Patients hospitalized for COVID-19 display marked impairment in endothelial function, which is persistent following recovery from the acute infection. • Red blood cells (RBCs) from patients with COVID-19 impair vascular function through mechanisms involving increased arginase 1...

SARS-CoV-2 Infects Red Blood Cell Progenitors and Dysregulates Hemoglobin and Iron Metabolism Romy Kronstein‐Wiedemann, Marlena Stadtmüller, Sofia Traikov, Mandy Georgi, Madeleine Teichert, Hesham Yosef, Jan Wallenborn, Andreas Karl, Karin Schütze, Michael Wagner, Ali El‐Armouche, Torsten Tonn...

Moved post International Journal of Molecular Sciences Implication of Covid-19 on Erythrocytes Functionality: Red Blood Cell Biochemical Implications and Morpho-Functional Aspects by Annamaria Russo et al Abstract Several diseases (such as diabetes, cancer, and neurodegenerative disorders)...

Abstract Background Altered red blood cell (RBC) deformability has been reported in Veterans with Gulf War Illness (GWI) who endorse exercise-induced symptom exacerbation and fatigue. However, it is unknown whether altered RBC deformability is worsened secondary to exercise. Objective To...

Red blood cell deformability is diminished in patients with Chronic Fatigue Syndrome Amit K. Saha, Brendan R. Schmidt, Julie Wilhelmy, Vy Nguyen, Abed Abugherir, Justin K. Do, Mohsen Nemat-Gorgani, Ronald W. Davis Clinical Hemorheology and Microcirculation 71 (2019) 113–116 DOI...

Red Blood Cell Deformability, Vasoactive Mediators, and Adhesion Timothy J. McMahon Open Access Healthy red blood cells (RBCs) deform readily in response to shear stress in the circulation, facilitating their efficient passage through capillaries. RBCs also export vasoactive mediators in...

Both red blood cells damage and kynurine identified in LongCovid research https://news.cuanschutz.edu/news-stories/attack-on-red-blood-cells-a-prime-suspect-in-covids-debilitating-effects?fbclid=IwAR2BjzW8TolU6d1b-VxUN-n6F55E6dMVcMwGkMR-huuW-wbi8mEvqTNJt-s

I found it interesting that the affected genes in the study (ALAD and p16) are involved in red blood cell development and some cancers. Lead poisoning could reduce gene expression in humans Scientists have unveiled a correlation between high blood lead levels in children and methylation of...

www.bloodjournal.org/content/132/Suppl_1/4874 At the moment, the full article is not yet available. Edit: We have 3 threads on related or the same research by the same team: Erythrocyte Deformability As a Potential Biomarker for Chronic Fatigue Syndrome, Davis et al (2018) Altered Erythrocyte...

Paywalled at https://content.iospress.com/articles/clinical-hemorheology-and-microcirculation/ch170262