paediatric

Post-COVID-19 syndrome in children and young people: awareness among paediatric trainees in South Wales Ahmed N, Vallabhaneni P Abstract Introduction Post-COVID-19 condition (PCS), commonly known as Long COVID, has been increasingly reported among children, particularly those of school age...

Background Recent proteomic studies have documented that Long COVID in adults is characterized by a pro-inflammatory signature with thromboinflammation. However, if similar events happen also in children with Long COVID has never been investigated. Methods We performed an extensive protein...

Abstract Introduction Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition that can affect adolescents during a vulnerable period of development. The underlying biological mechanisms for ME/CFS remain unclear and have rarely been investigated in the adolescent...

Background Predicting which children and young people (CYP) are at the highest risk of developing post-COVID-19 condition (PCC) could improve care pathways. We aim to develop and validate prediction models for persistent PCC up to 24 months post-infection in CYP. Methods CYP who were...

Introduction: Postural orthostatic tachycardia syndrome is a debilitating disorder. We compared paediatric patients with this dysautonomia presenting with and without peak upright heart rate > 100 beats per minute. Materials and methods: Subjects were drawn from the Postural Orthostatic...

Camille A. Broussard, MD, MPHa,*, Alba Azola, MDb,c, Peter C. Rowe, MDd Pediatric Clinics of North America (2024) Post-acute sequelae of SARS CoV-2 infection (PASC) in adolescents and young adults (AYAs) presents heterogeneously, often with multisystem involvement. Between 3 and 6 months...

Graded exercise therapy compared to activity management for paediatric chronic fatigue syndrome/myalgic encephalomyelitis: pragmatic randomized controlled trial Gaunt, Daisy M.; Brigden, Amberly; Harris, Shaun R. S.; Hollingworth, William; Jago, Russell; Solomon-Moore, Emma; Beasant, Lucy...

Now published - link here Preprint Pediatric and Adult Patients with ME/CFS following COVID-19: A Structured Approach to Diagnosis Using the Munich Berlin Symptom Questionnaire MBSQ Laura C. Peo; Katharina Wiehler; Johannes Paulick; Katrin Gerrer; Ariane Leone; Anja Viereck; Matthias Haegele...

Investigating the factors associated with meaningful improvement on the SF-36-PFS and exploring the appropriateness of this measure for young people with ME/CFS accessing an NHS specialist service: a prospective cohort study Daisy Gaunt; Amberly Brigden; Chris Metcalfe; Maria Loades; Esther...

Objectives Paediatric Chronic Fatigue Syndrome (pCFS) is a common condition that significantly disrupts a healthy psychosocial development. Psychiatric symptoms associated with pCFS are conceptualized as either part of its complex etiology, its consequence, or as a comorbidity. However...

What lies beneath: White matter microstructure in pediatric myalgic encephalomyelitis/chronic fatigue syndrome using diffusion MRI Elisha K. Josev; Jian Chen; Marc Seal; Adam Scheinberg; Rebecca C. Cole; Katherine Rowe; Lionel Lubitz; Sarah J. Knight Recent studies in adults with myalgic...

https://longcovidadvocacy.substack.com/p/is-the-greatest-medical-scandal-of Is the “greatest medical scandal of the last century" being repeated for a generation of children? Part One - The CLoCK Files, the Crisis in Paediatric Long Covid In July 2022 Long Covid Advocacy wrote a formal...

Background: Fatigue is a common, nonspecific complaint commonly used to describe various conditions, ranging from a vague, subjective sense of weariness to muscular weakness, fatigability, exercise intolerance or excessive daytime somnolence. Despite its high frequency in the general population...

Abstract Objectives Primary objective: to determine the point prevalence and incidence rate of severe myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in children aged 5–16 years over 13 months. Secondary objectives: to describe the demographic features, symptoms, impact on activities...

Full title: The importance of school in the management of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): issues identified by adolescents and their families Abstract Paediatric Myalgic Encephalomyelitis (ME)/Chronic Fatigue Syndrome (CFS) is a disabling condition. Schools play a...

Not sure which forum to post this to but it looks interesting. https://www.hindawi.com/journals/prm/2021/6627864/ Research Article | Open Access Volume 2021 |Article ID 6627864 | https://doi.org/10.1155/2021/6627864 Impaired Mitochondrial Bioenergetics Function in Pediatric Chronic...

Paroxysmal exercise-induced neurological symptoms (PENS) encompass a wide spectrum of clinical phenomena commonly presenting during childhood and characteristically elicited by physical exercise. Interestingly, few shared pathogenetic mechanisms have been identified beyond the well-known entity...

https://pubmed.ncbi.nlm.nih.gov/33978163/

Recovery from chronic fatigue syndrome: a systematic review—heterogeneity of definition limits study comparison Yasmin Moore Teona Serafimova Nina Anderson Hayley King Alison Richards Amberly Brigden Parisa Sinai Julian Higgins Caitlin Ascough Philippa Clery Esther M Crawley Open access...

https://www.ruh.nhs.uk/patients/services/clinical_depts/paediatric_cfs_me/index.asp https://www.ruh.nhs.uk/patients/services/clinical_depts/paediatric_cfs_me/documents/POMME_Study_Info_June 2020.pdf eta: an apple a day keeps the doctor away?