muscle

Abstract During maximal exercise healthy humans increase their oxygen uptake (V̇O2) 10 to 20-fold that measured at rest to as much as 6 L/min. At the molecular level the numbers are staggering: Each minute the exercising O2 transport system - lungs, cardiovascular and active muscles – must...

Serum GDF-15 Levels Accurately Differentiate Patients with Primary Mitochondrial Myopathy, Manifesting with Exercise Intolerance and Fatigue, from Patients with Chronic Fatigue Syndrome Authors from the Neuromuscular Disorders Unit of the Hospital Universitario 12 de Octubre in Madrid (national...

Precision MRI phenotyping of muscle volume and quality at a population scale Marjola Thanaj, Nicolas Basty, Brandon Whitcher, Elena P Sorokin, Yi Liu, Ramprakash Srinivasan, Madeleine Cule, Elizabeth Louise Thomas, Jimmy David Bell Background: Magnetic resonance imaging (MRI) enables direct...

Post-COVID syndrome is associated with capillary alterations, macrophage infiltration and distinct transcriptomic signatures in skeletal muscles Tom Aschman, Emanuel Wyler, Oliver Baum, Andreas Hentschel, Franziska Legler, Corinna Preusse, Lil Meyer-Arndt, Ivana Buettnerova, Alexandra Foerster...

Abstract Background Muscle fatigue and pain are key symptoms of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). Although the pathophysiology is not yet fully understood, there is ample evidence for hypoperfusion which may result in electrolyte imbalance and sodium overload in...

Abstract Background Patients with long-COVID often complain of continuous fatigue, myalgia, sleep problems, cognitive dysfunction, and post-exertional malaise. No data are available on EMG recording of evoked myopotentials (M-waves) or exercise-induced alterations in long-COVID patients...

Pain is not one of my usual ME/CFS symptoms. When I overexert myself physically and subsequently have post-exertional malaise, my muscles (especially those which I used the most) feel leaden, sore, but not stiff, and they burn. I can relate to the often used description of feeling “poisoned”...

In this article we review complications to the peripheral nervous system that occur as a consequence of viral infections, with a special focus on complications of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). We discuss neuromuscular complications in three broad categories; the...

Myopathy as a cause of fatigue in long-term post-COVID-19 symptoms: Evidence of skeletal muscle histopathology Eva K Hejbøl, Thomas Harbo, Jane Agergaard, Line B Madsen, Thomas H Pedersen, Lars J Østergaard, Henning Andersen, Henrik D Schrøder, Hatice Tankisi Background: Among post-COVID-19...

Apologises if this has been posted - I searched and could not find it. Intramuscular Pressure is Almost Three Times Higher in Fibromyalgia Patients: A Possible Mechanism for Understanding the Muscle Pain and Tenderness https://www.jrheum.org/content/early/2020/09/10/jrheum.191068 Robert S...

Note, this is a study from 1992 is posted for potential future reference. Background Previous study of patients with chronic fatigue syndrome (CFS) has demonstrated a markedly reduced dynamic exercise capacity, not limited by cardiac performance and in the absence of clinical neuromuscular...

Note that this is a study from 1998 and is posted for potential future reference. Abstract It has been shown previously that some patients with chronic fatigue syndrome show an abnormal increase in plasma lactate following a short period of moderate exercise, in the sub-anaerobic threshold...

I came across this paper while looking at a Peter Behan paper from 1985. This paper is from his colleagues using Behan's patients. Abstract Single fibre electromyography (SFEMG) was studied in 40 patients with the post-viral fatigue syndrome. These patients were also assessed clinically...

Abstract Chronic Fatigue Syndrome or Myalgic Encephaloymelitis (ME/CFS) is a frequent debilitating disease with an enigmatic etiology. The finding of autoantibodies against ß2-adrenergic receptors (ß2AdR) prompted us to hypothesize that ß2AdR dysfunction is of critical importance in the...

Winter sees a downturn for my daughter and she is having real issues with muscles - this post is to sound out how " normal" her experience is for ME, in case it's not! i have managed to organise a GP home visit next week which will deal with this and some other issues, but any info gratefully...

Full title: Chronic fatigue syndrome: Abnormally fast muscle fiber conduction in the membranes of motor units at a low-level static force load Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1388245721000122

Hey We recently had the study which showed impaired glucose utilization in muscle biopsy samples Anyone know if we have more studies from muscle biopsies? Im thinking about having one myself out of curiosity, and want some references I think history might show that the above mentioned study...

Paywall, https://journals.lww.com/acsm-msse/Abstract/9000/Exercise_Intolerance_in_Cystic_Fibrosis_.96154.aspx Sci hub, unable to access.

In mice. Open access PDF available at https://physoc.onlinelibrary.wiley.com/doi/10.1113/JP280758

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-020-02341-9?utm_source=other&utm_medium=other&utm_content=null&utm_campaign=BSCN_2_DD01_CN_bmcso_article_paid_XMOL