migraine

Rami Burstein 1, Rodrigo Noseda 1, Anne B Fulton 1 Abstract Background: Photophobia is commonly associated with migraine, meningitis, concussion, and a variety of ocular diseases. Advances in our ability to trace multiple brain pathways through which light information is processed have paved...

Ubrogepant for the treatment of migraine prodromal symptoms: an exploratory analysis from the randomized phase 3 PRODROME trial Peter J. Goadsby, Jessica Ailani, David W. Dodick, Amaal J. Starling, Chengcheng Liu, Yingyi Liu, Sung Yun Yu, Jonathan H. Smith, Elimor Brand-Schieber & Joel M...

PACAP activates MRGPRX2 on meningeal mast cells to drive migraine-like pain Sbei, Sami; Moncrief, Taylor; Limjunyawong, Nathachit; Zeng, Yaping; Green, Dustin P. Migraine ranks among the most prevalent disorders worldwide, leading to disability and decreased quality of life in patients...

Post Acute Sequelae from SARS-CoV-2 (PASC) at University of Illinois Hospital and Clinics – An Examination of the Effects of Long COVID in an Underserved Population, Utilizing Manual Extraction of Electronic Health Records John Musachia, Jon Radosta, Dirin Ukwode, Shahrukh Rizvi, Romani Wahba...

Sex-related differences in the association between migraine, COVID-19, and long COVID: A population-based cohort Linda Al-Hassany, Antoinette - MaassenVanDenBrink, Tobias Kurth [Line breaks added] Abstract Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, placed...

Dear Colleagues, Migraine presents significant public health burden. This condition presents central nervous system (CNS) disorder affecting nerves and blood vessels. Previously it was stated that migraine presents risk factor for cardiovascular diseases. Persons with migraine can have multiple...

Title: Insights from triggers and prodromal symptoms on how migraine attacks start: The threshold hypothesis Authors: Sebastianelli G, Atalar AÇ, Cetta I, et al. Abstract Background The prodrome or premonitory phase is the initial phase of a migraine attack, and it is considered as a...

Background Chronic overlapping pain conditions (COPCs), pain-related conditions that frequently occur together, may occur in patients with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and could impact illness severity. This study aimed to identify comorbid COPCs in patients with...

Subjective brain fog: a four-dimensional characterization in 25,796 participants Ali Alim-Marvasti, Matteo Ciocca, Narayan Kuleindiren, Aaron Lin, Hamzah Selim, Mohammad Mahmud Abstract Importance: Brain fog is associated with significant morbidity and reduced productivity and gained...

Patient perceptions of barriers to effective migraine management in Aotearoa New Zealand Blair McInnarney; Fiona Imlach; Jonathan Kennedy; Susan M. Garrett INTRODUCTION Migraine is a complex neurological condition which requires evidence based treatment, tailored to the individual...

Using acid reflux drugs is linked to higher migraine risk, study warns (msn.com)

Conclusion In the past few years, we have made great progress in understanding the mechanism of energy metabolism in migraine. KCL-induced CSD and nitroglycerin-induced cerebral vasodilation are commonly used migraine models, which can cause disorders of energy metabolism and lead to oxidative...

SARS-CoV-2 induces acute neurological signs while Calcitonin Gene-Related Peptide CGRP signaling blockade reduces interleukin 6 IL-6 release and weight loss in mouse models Shafaqat M Rahman; David W Buchholz; Brian Imbiakha; Mason C Jaeger; Justin Leach; Raven M Osborn; Ann O Birmingham...

Our results show that glutamate and serotonin are involved in brain connectivity alterations in areas of the visual, salience, and limbic systems in VSS. Importantly, altered serotonergic connectivity is independent of migraine in VSS, and simultaneously comparable to that of migraine with aura...

Does anyone else here suffer from ocular or visual migraines during PEM? I have them with aura sometimes too. No headaches though. Have you gotten to try any treatments, and if so did they help? Are there any existing threads on this? I couldn't find any but maybe I'm using the wrong name for...

Abstract Background Migraine carries risk of myocardial infarction (MI) and stroke. The risk of premature MI (i.e., among young adults) and stroke differs between men and women; previous studies indicate that migraine is mainly associated with an increased risk of stroke among young women. The...

FDA approves world’s first fast-acting nasal spray to treat migraines (msn.com)

The trial will assess the safety and efficacy of TNX-1900 given prophylactically daily for preventing chronic migraines. https://www.clinicaltrialsarena.com/news/tonix-migraine-therapy-trial/

Abstract Objective To contextualize migraine as the most common primary headache disorder in relation to other chronic primary pain and non-pain functional somatic and mental conditions. Background Migraine is increasingly understood as a sensory processing disorder within a broader spectrum...

Objective: To assess the prevalence and burden of autonomic symptoms in migraine, and determine the relationship with migraine frequency. Background: Autonomic symptoms in migraine have been theorized to occur in the setting of inter-ictal sympathetic hypoactivity and hyper-sensitivity. There...