me/cfs

Abstract: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a chronic and debilitating disease with unknown cause. Involvement of infection and immune dysregulation has been suggested, including changes in immune cell subsets and abnormal functions of natural killer (NK) cells. The...

The emerging role of exosomal LncRNAs in chronic fatigue syndrome: from intercellular communication to disease biomarkers Lei Wang, Yujia Xu, Xiang Zhong, Guiping Wang, Zijun Shi, Can Mei, Linwanyue Chen, Jianbo Zhan, Jing Cheng [Line breaks added] Abstract Chronic fatigue syndrome (CFS) is a...

Abstract: Background Myalgic encephalomyelitis (ME) is a chronic, multisystem illness characterized by post-exertional malaise (PEM) and cognitive dysfunction, yet the molecular mechanisms driving these hallmark symptoms remain unclear. This study investigated haptoglobin (Hp) as a potential...

Abstract: Background Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex and debilitating condition with a large proportion of patients that experience orthostatic intolerance (OI). This systematic review aimed to assess whether cerebral blood flow (CBF) is reduced in ME/CFS...

An integrative review on the orexin system and hypothalamic dysfunction in myalgic encephalomyelitis/chronic fatigue syndrome: implications for precision medicine Noé López-Amador [Line breaks added] Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating...

ME/CFS and Long Covid: Diagnosis and management of chronic fatigue syndromes Gavin Spickett [Line breaks added] Abstract This book covers the history and characteristic symptoms of ME/CFS and Long Covid in adults. Children are not discussed in detail. It discusses the extensive differential...

A first study of cytokine genomic polymorphisms in CFS: Positive association of TNF-857 and IFNgamma 874 rare alleles N Carlo-Stella, C Badulli, A De Silvestri, L Bazzichi, M Martinetti, L Lorusso, S Bombardieri, L Salvaneschi, M Cuccia Published: 2006 [Line breaks added] Objective In the...

Prospective associations between major depressive disorder, generalized anxiety disorder, fibromyalgia, and myalgic encephalomyelitis/chronic fatigue syndrome Nathaniel Stembridge Thomas, Michael C. Neale, Kenneth S. Kendler, Hanna M. van Loo, Nathan A. Gillespie Background Functional...

Circulating cell-free RNA signatures for the characterization and diagnosis of myalgic encephalomyelitis/chronic fatigue syndrome Anne E. Gardella, Daniel Eweis-LaBolle, Conor J. Loy, Emma D. Belcher, Joan S. Lenz, Carl J. Franconi, Sally Y. Scofield, Andrew Grimson, Maureen R. Hanson, Iwijn De...

Abstract: Autoimmunity is a key clinical feature in both post-infectious Myalgic encephalomyelitis / chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of COVID (PASC). Passive transfer of immunoglobulins from patients' sera into mice induces some clinical features of PASC. IgG-induced...

ABSTRACT Background: Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a disabling condition associated with substantial functional impairment. Although historically considered non-fatal, recent studies have suggested a link between ME/CFS and premature mortality. Objective: To...

Effect of nonpharmacologic therapies on depressive symptoms in patients with chronic fatigue syndrome: a network meta-analysis Baiyi Jiang, Mengru Cao, Xue Xia, Long Wang Background Depression or depressive symptoms exacerbate the burden in patients with chronic fatigue syndrome (CFS). The...

Causes of symptoms and symptom persistence in long COVID and myalgic encephalomyelitis/chronic fatigue syndrome Anthony L. Komaroff, Robert Dantzer Abstract Debilitating symptoms for many years can follow acute COVID-19 (“long COVID”), myalgic encephalomyelitis/chronic fatigue syndrome...

Beyond fatigue: an intersectional analysis of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and social identities Zoe Sirotiak, Emily B. K. Thomas [Line breaks added] Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex, chronic condition...

*This post is in the process of being updated. People have given me feedback that sharing the Bluesky/Twitter threads is not a preferred/accessible option, so I will try to convey the relevant info here (it will likely have to be spread across multiple threads focusing on sub-topics). This will...

Question: has anyone made an overview of publicly available dataset on ME/CFS? For example a list with links to papers or repositories where the ME/CFS dataset is available and can be downloaded by anyone, perhaps classified by topics such as immunology, metabolomics ..., etc.?

Beneficial effects of intermittent intravenous saline infusion in dysautonomic patients with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: a caseseries Per Sjogren, Helena Huhmar, Bo Christer Bertilson, Björn A Bragée, Olli Polo [Line breaks added] Purpose Myalgic...

What Doesn't Kill You Lives in the grip of ME/CFS ✓ Coming in 2025 ✓ 100% of profit reinvested in ME/CFS research and education "What Doesn't Kill You" is a forthcoming documentary exploring the lives of people battling ME/CFS, a scandalously underfunded and chronically ignored disease...

Multifaceted evolution focused on maximal exploitation of domain knowledge for the consensus inference of Gene Regulatory Networks Adrián Segura-Ortiz, Karen Giménez-Orenga, José García-Nieto, Elisa Oltra, José F. Aldana-Montes [Line breaks added] Highlights • BIO-INSIGHT optimizes GRN...

Affective and chronic fatigue symptoms are associated with serum neuronal damage markers in Parkinson’s disease Hussein Kadhem Al-Hakeim, Hayder Naji Khudhair, Sayed-Omid Ranaei-Siadat, Fataneh Fatemi, Fateme Mirzajani , Mengqi Niu & Michael Maes [Line breaks added] Abstract Parkinson’s...