Fibromyalgia, Chronic Fatigue Syndrome, and Multiple Sclerosis are associated with lower translocator protein binding affinity genotypes
Jones, Chloe; Younger, Jarred
Introduction
Neuroinflammation is a known pathophysiologic mechanism in multiple sclerosis and a proposed mechanism in...
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Post-Acute Sequelae of SARS-CoV-2 infection (Long COVID) are complex multisystem disorders affecting 60–400 million individuals globally. They are considered post-infectious illnesses and share similar biological...
Estimation of ME/CFS among individuals with long COVID in an Austrian online support group
Zach, D; Waldhoer, T; Felsinger, R; Kapan, A
Background
Long COVID is frequently characterised by fatigue, cognitive dysfunction and post-exertional malaise (PEM), overlapping with Myalgic...
A Woman With Multiple Neuropathic Symptoms, Hypersensitivity to Heat, Peppers, and Alcohol, With a Variant in the TRPV1 Capsaicin Receptor Gene: Possible Implications to ME/CFS
Zimmermann, Phillip M.; Boles, Richard G.
Abstract
Transient receptor potential vanilloid 1 (TRPV1) is a ligand and...
There's been some discussion of ACTH response recently, so it seemed like a good idea to see all the findings together. Thanks to members who already posted and linked some of these papers. I found some more through PubMed and Google Scholar.
I'm not sure if I found all of the studies that...
Stress-induced changes in LPS-induced pro-inflammatory cytokine production in chronic fatigue syndrome
Gaab, Jens; Rohleder, Nicolas; Heitz, Vera; Engert, Veronika; Schad, Tanja; Schürmeyer, Thomas H.; Ehlert, Ulrike
OBJECTIVE
It has been suggested that a hypofunctional...
Associations between neuroendocrine responses to the Insulin Tolerance Test and patient characteristics in chronic fatigue syndrome
Gaab, Jens; Engert, Veronika; Heitz, Vera; Schad, Tanja; Schürmeyer, Thomas H; Ehlert, Ulrike
Objective
Subtle dysregulations of the...
Hypothalamic-Pituitary-Adrenal Axis Reactivity in Chronic Fatigue Syndrome and Health Under Psychological, Physiological, and Pharmacological Stimulation
Jens Gaab, Dominik Hüster, Renate Peisen, Veronika Engert, Vera Heitz, Tanja Schad, Thomas H. Schürmeyer, Ulrike Ehlert
Abstract
Subtle...
Hypothalamo-Pituitary-Adrenal Axis Dysfunction in Chronic Fatigue Syndrome, and the Effects of Low-Dose Hydrocortisone Therapy
Cleare, A. J.; Miell, J.; Heap, E.; Sookdeo, S.; Young, L.; Malhi, G. S.; O’Keane, V.
Abstract
These neuroendocrine studies were part of a series of studies testing...
Characterization of pituitary function with emphasis on GH secretion in the chronic fatigue syndrome
Moorkens, Greta; Berwaerts, Joris; Wynants, Herlindis; Abs, Roger
Objective
Previous studies have revealed that hormonal disturbances may accompany the chronic fatigue syndrome (CFS). Changes...
Desmopressin augments pituitary–adrenal responsivity to corticotropin-releasing hormone in subjects with chronic fatigue syndrome and in healthy volunteers
Scott, Lucinda V; Medbak, Sami; Dinan, Timothy G
Background
Corticotopin-releasing hormone (CRH) and vasopressin (VP) are the two...
Naloxone-mediated activation of the hypothalamic–pituitary–adrenal axis in chronic fatigue syndrome
L.V. Scott, F. Burnett, S. Medbak, T.G. Dinan
Background
Opioidergic pathways have an inhibitory regulatory influence on the hypothalamic–pituitary–adrenal axis (HPA) in man. Previous studies...
Blunted adrenocorticotropin and Cortisol responses to corticotropin‐releasing hormone stimulation in chronic fatigue syndrome
Scott, L. V.; Medbak, S.; Dinan, T. G.
Abstract
Hyperfunctioning of the pituitary‐adrenal axis has been suggested as the pathophysiological basis for chronic fatigue...
Understanding the aetiology of Myalgic encephalomyelitis
Gemma Louise Samms
Background
ME/CFS is a devastating condition that lacks effective treatments. Those affected experience debilitating symptoms and little healthcare or societal support. There are diagnostic challenges associated with...
Deciphering the Pathophysiological Basis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Review of Emergent Research and Scientific Progress
Christina N. Forsythe, PMP, MS, MT(ASCP)
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating, globally...
Identification of SGK1 as a candidate regulator associated with myeloid cell senescence in ME/CFS: An integrative transcriptomic and experimental study
Jin, Yan; Qin, Rui; Li, Wan; Liu, Jin; Chen, Xinghua
Background
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex...
Bidirectional interaction between ferroptosis and chronic fatigue syndrome: Insights into neuroinflammation and oxidative stress
Abstract
Chronic fatigue syndrome (CFS) is a multisystem disease of unknown aetiology. It disrupts multiple physiological systems, and its pathogenesis, reliable...
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