lyme

https://bjgplife.com/delicate-diagnosis-avoiding-harms-in-difficult-disputed-and-desired-diagnoses/ BJGP LONG READ ‘Delicate diagnosis’: avoiding harms in difficult, disputed, and desired diagnoses 7 October 2022 Margaret McCartney is an Honorary Senior Lecturer at the School of Medicine...

Abstract Previous studies have shown that monocytes can be ‘trained’ or tolerized by certain stimuli to respond stronger or weaker to a secondary stimulation. Rewiring of glucose metabolism was found to be important in inducing this phenotype. As we previously found that Borrelia burgdorferi...

Since Lyme Disease gets mentioned on the forum from time to time I thought this video might be of interest :

https://www.pfizer.com/news/press-release/press-release-detail/pfizer-and-valneva-initiate-phase-3-study-lyme-disease

Full title: Six versus 2 weeks treatment with doxycycline in European Lyme neuroborreliosis: a multicentre, non-inferiority, double-blinded, randomised and placebo-controlled trial Abstract Background There is limited evidence regarding optimal duration of antibiotic treatment in...

Abstract Public health reports contain limited information regarding the psychological and neurological symptoms of tick-borne diseases (TBDs). Employing a mixed-method approach, this analysis triangulates three sources of symptomology and provides a comparison of official public health...

Full title: Efficacy of Short-Term High Dose Pulsed Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-Infections: A Report of Three Cases and Literature Review Abstract Lyme disease and associated co-infections...

Full title: Predicting distributions of blacklegged ticks (Ixodes scapularis), Lyme disease spirochetes (Borrelia burgdorferi sensu stricto) and human Lyme disease cases in the eastern United States Abstract Lyme disease is the most commonly reported vector-borne disease in the United States...

Full title: Management and clinical outcomes of Lyme disease in acute care facilities in 2 endemic regions of Quebec, Canada: a multicentre retrospective cohort study Abstract Background: Despite increases in cases of Lyme disease, little is known about the management and clinical course of...

Posts moved from this thread: The science of craniocervical instability and other spinal issues and their possible connection with ME/CFS - discussion thread Absolutely. The advocacy community commonly argues that chronic Lyme disease is grossly underdiagnosed and is responsible for an...

Abstract Background: Prior studies have demonstrated that Lyme disease is frequently over-diagnosed. However, few studies describe which conditions are misdiagnosed as Lyme disease. Methods: This retrospective observational cohort study evaluated patients referred for Lyme disease to a...

Merged thread For the abstract of the paper and a link to it, see this post. The discovery that a chemical is deadly to the bacterium that causes Lyme disease but harmless to animals might allow the disease to be eradicated in the wild. “Lyme disease is well-positioned to be eradicated,”...

https://www.nytimes.com/2021/10/23/opinion/lyme-disease-chronic-illness.html Ross Douthat is a columnist for The NY Times. He is both a political and religious conservative. He contracted Chronic Lyme disease and wrote a book about it (he has mostly recovered). This column is an excerpt from...

Objectives(s): To characterise the clinical profile, aetiology and treatment responsiveness of ‘Australian Lyme’, or Debilitating Symptom Complexes Attributed to Ticks. Methods: Single-centre retrospective case analysis of patients referred to the Infectious Diseases Unit at Austin Health – a...

New Phage based test for borrelia A new Phage based test has been developed to detect borrelia bacteria in collaboration between Leicester University (Dr Martha Clokie https://www2.le.ac.uk/departments/genetics/people/martha-clokie) and Phelix (Dr Louis Teulières) Paper here: Info about...

Lyme disease: 'People say I don't look ill' - BBC News Yen Lau caught Lyme disease from an infected tick bite during a camping trip to Loch Lomond almost four years ago. She says she is living with an "invisible disease" that today still causes her days-long bouts of sickness, migraines...

First Clinical Study of the Safety and Blood Levels of a Human Monoclonal Antibody (2217LS) Against Lyme Disease Bacteria in Healthy People, 2021, MassBiologics, Phase I Study Type : Interventional (Clinical Trial) Estimated Enrollment : 48 participants Allocation: Randomized Intervention...

Detecting Borrelia Spirochetes: A Case Study With Validation Among Autopsy Specimens Authors Shiva Kumar Goud Gadila, Gorazd Rosoklija, Andrew J. Dwork, Brian A. Fallon, Monica E. Embers Abstract The complex etiology of neurodegenerative disease has prompted studies on multiple mechanisms...

A comprehensive clinical and laboratory evaluation of 224 patients with persistent symptoms attributed to presumed tick-bite exposure Abstract Background: Persistent symptoms attributed to presumed tick-bite exposure constitute an unresolved medical controversy. We evaluated whether Swedish...

Open access, full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690415/