Katherine Huang, Alex G. C. de Sá, Natalie Thomas, Robert D. Phair, Paul R. Gooley, David B. Ascher & Christopher W. Armstrong
Abstract
Background
Diagnosing complex illnesses like Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is complicated due to the diverse symptomology and...
A six-year study in a real-world population reveals an increased incidence of dyslipidemia during COVID-19
Valentina Trimarco; Raffaele Izzo; Stanislovas S. Jankauskas; Mario Fordellone; Giuseppe Signoriello; Maria Virginia Manzi; Maria Lembo; Paola Gallo; Giovanni Esposito; Roberto Piccinocchi...
There is compelling evidence that a dysregulated immune inflammatory response in neuroinfectious diseases results in modifications in metabolic processes and altered metabolites, directly or indirectly influencing lipid metabolism within the central nervous system (CNS).
The challenges in...
Targeted metabolomics identifies accurate CSF metabolite biomarkers for the differentiation between COVID-19 with neurological involvement and CNS infections with neurotropic viral pathogens
Neu, Frieder; Nay, Sandra; Schuchardt, Sven; Klawonn, Frank; Skripuletz, Thomas; Suehs, Kurt-Wolfram...
Now published - see post #20
Ruoyun Xiong,
Elizabeth Aiken,
Ryan Caldwell,
Suzanne D. Vernon,
Lina Kozhaya,
Courtney Gunter,
Lucinda Bateman,
Derya Unutmaz &
Julia Oh
********************************
https://www.biorxiv.org/content/10.1101/2024.06.24.600378v1
BioMapAI: Artificial Intelligence...
Quantitative imaging of species-specific lipid transport in mammalian cells
Juan M. Iglesias-Artola; Kai Schumann; Kristin Bohlig; H. Mathilda Lennartz; Milena Schumacher; Pavel Barahtjan; Cristina Jiminez Lopez; Radek Sachl; Karina Pombo-Garcia; Annett Lohmann; Petra Riegerova; Martin Hof...
Abstract
Background
This study investigates the impact of fluctuating lipid levels on endothelial dysfunction.
Methods
Human aortic and umbilical vein endothelial cells were cultured under varying palmitic acid (PA) concentrations: 0, 50, and 100 μM, and in a variability group alternating...
Now published - see post #6
Preprint
Persistent Activation of Chronic Inflammatory Pathways in Long Covid
Malika Aid; Katherine McMahan; Nicole Hachmann; Jessica Miller; Erica Borducchi; David Hope; Marjorie Rowe; Eleanor Schonberg; Siline Thai; Ai-ris Collier; Janet Mullington; Dan Barouch...
Oxidative Stress is a shared characteristic of ME/CFS and Long COVID
Vishnu Shankar; Julie Wilhelmy; Basil Michael; Layla Cervantes; Vamsee Mallajosyula; Ronald Davis; Michael Snyder; Shady Younis; William H Robinson; Sadasivan Shankar; Paul Mischel; Hector Bonilla; Mark Davis
More than 65...
calcium
glutathione
gpx4
lipid droplets
lipids
mark davis
metformin
mitochondria
oxidative stress
reactive oxygen species
ron davis
sex differences
t cells
Subcellular imaging of lipids and sugars using genetically encoded proximity sensors
William M. Moore; Roberto J. Brea; Caroline Knittel; Ellen Wrightsman; Brandon Hui; Jinchao Loui; Christelle F. Ancajas; Michael D. Best; Neal K. Devaraj; Itay Budin
Live cell imaging of lipids and other...
Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids
Fava, Marina; De Dominicis, Noemi; Forte, Giulia; Bari, Monica; Leuti, Alessandro; Maccarrone, Mauro
Microgravity is one of the main stressors that astronauts are exposed to during space missions...
Anti-Nociceptive Effects of Sphingomyelinase and Methyl-Beta-Cyclodextrin in the Icilin-Induced Mouse Pain Model
Horváth, Ádám; Steib, Anita; Nehr-Majoros, Andrea; Kántás, Boglárka; Király, Ágnes; Racskó, Márk; Tóth, Balázs István; Szánti-Pintér, Eszter; Kudová, Eva; Skoda-Földes, Rita; Helyes...
Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients Using a Multiplatform Mass Spectrometry-Based Metabolomics Approach
Sara Martínez; Oihane E. Albóniga; María Rosa López-Huertas; Ana Gradillas; Coral Barbas
Despite the recent and increasing knowledge surrounding...
Plasma Instead of Serum Avoids Critical Confounding of Clinical Metabolomics Studies by Platelets
Gerhard Hagn; Samuel M. Meier-Menches; Günter Plessl-Walder; Gaurav Mitra; Thomas Mohr; Karin Preindl; Andreas Schlatter; Doreen Schmidl; Christopher Gerner; Gerhard Garhöfer; Andrea Bileck...
Lipidomics signature in post-COVID patient sera and its influence on the prolonged inflammatory response
Abstract
Background: The ongoing issues with post-COVID conditions (PCC), where symptoms persist long after the initial infection, highlight the need for research into blood lipid changes...
Metabolic Fingerprinting for the Diagnosis of Clinically Similar Long COVID and Fibromyalgia Using a Portable FT-MIR Spectroscopic Combined with Chemometrics
Hackshaw, Kevin V.; Yao, Siyu; Bao, Haona; de Lamo Castellvi, Silvia; Aziz, Rija; Nuguri, Shreya Madhav; Yu, Lianbo; Osuna-Diaz, Michelle...
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