lipids
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Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.
Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...- SNT Gatchaman
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- coagulation endothelium lipid rafts lipids macrophages monocytes platelets sphingolipids sphingomyelin tissue factor
- Replies: 2
- Forum: Other health news and research
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Review Impact of sphingolipids on protein membrane trafficking, 2023, Aguilera-Romero et al.
Impact of sphingolipids on protein membrane trafficking Aguilera-Romero; Lucena; Sabido-Bozo; Muñiz Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination...- SNT Gatchaman
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- ceramide endoplasmic reticulum extracellular vesicles golgi lipid rafts lipids sphingolipids sphingomyelin
- Replies: 2
- Forum: Other health news and research
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Review Tale of two systems: the intertwining duality of fibrinolysis and lipoprotein metabolism, 2023, Dai et al.
Tale of two systems: the intertwining duality of fibrinolysis and lipoprotein metabolism Wen Dai; Mark Castleberry; Ze Zheng Fibrinolysis is an enzymatic process that breaks down fibrin clots, while dyslipidemia refers to abnormal levels of lipids and lipoproteins in the blood. Both...- SNT Gatchaman
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- annexin apo b coagulation fibrin fibrinolysis lipids plasminogen
- Replies: 3
- Forum: Other health news and research
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Circulating Metabolome and White Matter Hyperintensities in Women and Men, 2022, Sliz et al.
Circulating Metabolome and White Matter Hyperintensities in Women and Men Eeva Sliz; Jean Shin; Shahzad Ahmad; Dylan M. Williams; Stefan Frenzel; Friederike Gauß; Sarah E. Harris; Ann-Kristin Henning; Maria Valdes Hernandez; Yi-Han Hu; Beatriz Jiménez; Muralidharan Sargurupremraj; Carole Sudre...- SNT Gatchaman
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- brain hydroxyphenylpyruvate hyperintensities hypoxia lipids myelin sphingolipids sphingomyelin white matter
- Replies: 5
- Forum: Other health news and research
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Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling, 2023, Saunders et al.
Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling Nell Saunders; Blandine Monel; Nadege Cayet; Lorenzo Archetti; Hugo Moreno; Alexandre Jeanne; Agathe Marguier; Timothy Wai; Olivier Schwartz; Mathieu Frechin Assessing the impact of SARS-CoV-2 on...- SNT Gatchaman
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- covid 19 holotomographic microscopy lipid droplets lipids machine learning mitochondria sars-cov-2
- Replies: 2
- Forum: Epidemics (including Covid-19, not Long Covid)
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A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants, 2022, Farley et al.
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants Farley, Scotland E.; Kyle, Jennifer E.; Leier, Hans C.; Bramer, Lisa M.; Weinstein, Jules B.; Bates, Timothy A.; Lee, Joon-Yong; Metz, Thomas O.; Schultz, Carsten; Tafesse, Fikadu G. A comprehensive...- SNT Gatchaman
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- ceramide covid 19 lipid droplets lipidomics lipids plasmalogen sphingomyelin
- Replies: 2
- Forum: Epidemics (including Covid-19, not Long Covid)
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Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity & Early Mortality Prediction,2023,Lodge
Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity and Early Mortality Prediction Lodge, Samantha; Lawler, Nathan G.; Gray, Nicola; Masuda, Reika; Nitschke, Philipp; Whiley, Luke; Bong, Sze-How; Yeap, Bu B.; Dwivedi, Girish; Spraul...- SNT Gatchaman
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- ceramide kynurenine lipidomics lipids long covid mortality nicholson sphingolipids
- Replies: 1
- Forum: Long Covid research
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Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL, 2023, MOON et al.
Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL Moon, Jee-Young;Chai, Jin Choul;Yu, Bing;Song, Rebecca J.;Chen, Guo-Chong;Graff, Mariaelisa;Daviglus, Martha L.;Chan, Queenie;Thyagarajan, Bharat;Castaneda, Sheila F.;Grove...- SNT Gatchaman
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- amino acids deconditioning diabetes exercise hypertension lipids plasmalogen sedentary
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- Forum: Other health news and research
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Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle, 2022, McNally et al.
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle McNally, Ben D.; Ashley, Dean F.; Hänschke, Lea; Daou, Hélène N.; Watt, Nicole T.; Murfitt, Steven A.; MacCannell, Amanda D. V.; Whitehead, Anna; Bowen, T. Scott; Sanders...- SNT Gatchaman
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- ceramide endoplasmic reticulum er stress extracellular vesicles lipids lipotoxicity perk upr
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- Forum: Other health news and research
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Preprint Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis, 2023, Li et al.
Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis Jeson J Li; Nan Xin; Chunxia Yang; Larrisa A Tavizon; Ruth Hong; Travis I Moore; Rebecca G Tharyan; Adam Antebi; Hyun-Eui Kim Maintaining protein homeostasis is essential...- SNT Gatchaman
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- ceramide eif2a endoplasmic reticulum er stress hsp70 lipids mitochondria mortilin perk upr
- Replies: 8
- Forum: Other health news and research
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Hypothesis Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome, 2023, Sousa et al.
Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...- SNT Gatchaman
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- cognitive dysfunction covid ferritin ferroptosis gpx4 immune dysfunction inflammation iron lipids long covid myelin neuropsychiatric disorders
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- Forum: Long Covid research
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A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy, 2023, Southwell et al.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy Nneka Southwell; Guido Primiano; Viraj Nadkarni; Nabeel Attarwala; Emelie Beattie; Dawson Miller; Sumaitaah Alam; Irene Liparulo; Yevgeniya I Shurubor; Maria Lucia Valentino; Valerio Carelli; Serenella...- SNT Gatchaman
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- amino acids atf4 fatty acid oxidation fgf21 gdf15 integrated stress response lipid droplets lipids mitochondria mtor muscle myopathy tca cycle
- Replies: 4
- Forum: Other health news and research
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The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity, 2015, Heinz et al.
The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Heinz; Baumann; Köberlin; Snijder; Gawish; Shui; Sharif; Aspalter; Müller; Kandasamy; Breitwieser; Pichlmair; Bruckner; Rebsamen; Blüml; Karonitsch; Fauster; Colinge; Bennett; Knapp; Superti-Furga Lipid metabolism and...- SNT Gatchaman
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- immune system innate immune system lipids macrophages smpdl3b sphingomyelin tlr-4
- Replies: 2
- Forum: Other health news and research
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Preprint Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms, 2023, Romenskaja et al.
Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms Diana Romenskaja; Ugne Jonavice; Augustas Pivoriunas Autophagy dysfunction has been closely related with pathogenesis of many neurodegenerative diseases and therefore represents a potential...- SNT Gatchaman
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- autophagy extracellular vesicles lipid rafts lipids microglia tlr-4
- Replies: 2
- Forum: Other health news and research
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Associations of circulating metabolites with cerebral white matter hyperintensities, 2023, Sun et al.
Associations of circulating metabolites with cerebral white matter hyperintensities Yan Sun; Yu Guo; Hong-Qi Li; Lan Tan; Jian-Feng Feng; Wei Cheng; Jin-Tai Yu White matter hyperintensities (WMH) are the most compelling risk factors of stroke, dementia, and early mortality. We aimed to...- SNT Gatchaman
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- brain fatty acids lipids mri white matter
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- Forum: Other health news and research
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High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner, 2023, Correa et al.
High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner Correa; Del Giudice; Waldie; Thépaut; Micciula; Gerelli; Moulin; Delaunay; Fieschi; Pichler; Haertlein; Forsyth; Le Brun; Moir; Russell; Darwish; Brinck; Wodaje; Jansen; Martín...- SNT Gatchaman
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- cholesterol hdl lipids sars-cov-2 spike protein
- Replies: 2
- Forum: Epidemics (including Covid-19, not Long Covid)
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Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following (...), 2023, Achleitner et al
Full title: Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis Abstract In the aftermath of the COVID-19 pandemic, we are witnessing an unprecedented wave of post-infectious complications. Most...- Wyva
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- 2023 apheresis autoantibodies inflammation lipids long covid paper study
- Replies: 2
- Forum: Long Covid research
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Metabolic features of chronic fatigue syndrome 2016 Naviaux et al
Significance Chronic fatigue syndrome is a multisystem disease that causes long-term pain and disability. It is difficult to diagnose because of its protean symptoms and the lack of a diagnostic laboratory test. We report that targeted, broad-spectrum metabolomics of plasma not only revealed a...- Andy
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- amino acids lipids mitochondria sphingolipids
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- Forum: ME/CFS research
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Untargeted analysis in post-COVID-19 patients reveals dysregulated lipid pathways two years after recovery 2023 López-Hernández et al
Introduction: Similar to what it has been reported with preceding viral epidemics (such as MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human immunometabolism with long-term consequences. Even with underreporting, an accumulated of almost 650 million people have been...- Andy
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- lipids mexico phosphatidylcholine phospholipids sphingomyelin
- Replies: 6
- Forum: Long Covid research
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[Preprint] Immunometabolic rewiring in long COVID patients with chronic headache, 2023, Cleveland Clinic
Immunometabolic rewiring in long COVID patients with chronic headache Suan-Sin Foo, Weiqiang Chen, Kyle L Jung, Tamiris Azamor, Un Yung Choi, Pengfei Zhang, Suzy AA Comhair, Serpil C Erzurum, Lara Jehi, Jae U Jung Almost 20% of patients with COVID-19 experience long-term effects, known as...- SNT Gatchaman
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- arginine ceramide gaba headache kynurenine lipids long covid nitric oxide pro-inflammatory proteomics serotonin sphingomyelin
- Replies: 0
- Forum: Long Covid research