lipids
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Review Sphingolipids and their metabolism in physiology and disease, 2017, Hannun, Yusuf A. and Obeid, Lina M.
Sphingolipids and their metabolism in physiology and disease Hannun, Yusuf A.; Obeid, Lina M. Studies of bioactive lipids in general and sphingolipids in particular have intensified over the past several years, revealing an unprecedented and unanticipated complexity of the lipidome and its many...- SNT Gatchaman
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- ceramide endoplasmic reticulum er stress golgi histone lipid droplets lipid rafts lipids s1pr sphingolipids sphingomyelin upr
- Replies: 5
- Forum: Other health news and research
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Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis, 2023, Wang et al.
Alterations to Sphingomyelin Metabolism Affect Hemostasis and Thrombosis Jue Wang; Shiva Keshava; Kaushik Das; Richard Kolesnick; Xian-Cheng Jiang; Usha R. Pendurthi; L. Vijaya Mohan Rao BACKGROUND: Our recent studies suggest that sphingomyelin levels in the plasma membrane influence TF (tissue...- SNT Gatchaman
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- coagulation endothelium lipid rafts lipids macrophages monocytes platelets sphingolipids sphingomyelin tissue factor
- Replies: 2
- Forum: Other health news and research
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Review Impact of sphingolipids on protein membrane trafficking, 2023, Aguilera-Romero et al.
Impact of sphingolipids on protein membrane trafficking Aguilera-Romero; Lucena; Sabido-Bozo; Muñiz Membrane trafficking is essential to maintain the spatiotemporal control of protein and lipid distribution within membrane systems of eukaryotic cells. To achieve their functional destination...- SNT Gatchaman
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- ceramide endoplasmic reticulum extracellular vesicles golgi lipid rafts lipids sphingolipids sphingomyelin
- Replies: 2
- Forum: Other health news and research
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Review Tale of two systems: the intertwining duality of fibrinolysis and lipoprotein metabolism, 2023, Dai et al.
Tale of two systems: the intertwining duality of fibrinolysis and lipoprotein metabolism Wen Dai; Mark Castleberry; Ze Zheng Fibrinolysis is an enzymatic process that breaks down fibrin clots, while dyslipidemia refers to abnormal levels of lipids and lipoproteins in the blood. Both...- SNT Gatchaman
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- annexin apo b coagulation fibrin fibrinolysis lipids plasminogen
- Replies: 3
- Forum: Other health news and research
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Circulating Metabolome and White Matter Hyperintensities in Women and Men, 2022, Sliz et al.
Circulating Metabolome and White Matter Hyperintensities in Women and Men Eeva Sliz; Jean Shin; Shahzad Ahmad; Dylan M. Williams; Stefan Frenzel; Friederike Gauß; Sarah E. Harris; Ann-Kristin Henning; Maria Valdes Hernandez; Yi-Han Hu; Beatriz Jiménez; Muralidharan Sargurupremraj; Carole Sudre...- SNT Gatchaman
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- brain hydroxyphenylpyruvate hyperintensities hypoxia lipids myelin sphingolipids sphingomyelin white matter
- Replies: 5
- Forum: Other health news and research
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Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling, 2023, Saunders et al.
Dynamic label-free analysis of SARS-CoV-2 infection reveals virus-induced subcellular remodeling Nell Saunders; Blandine Monel; Nadege Cayet; Lorenzo Archetti; Hugo Moreno; Alexandre Jeanne; Agathe Marguier; Timothy Wai; Olivier Schwartz; Mathieu Frechin Assessing the impact of SARS-CoV-2 on...- SNT Gatchaman
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- covid 19 holotomographic microscopy lipid droplets lipids machine learning mitochondria sars-cov-2
- Replies: 2
- Forum: Epidemics (including Covid-19, not Long Covid)
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A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants, 2022, Farley et al.
A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants Farley, Scotland E.; Kyle, Jennifer E.; Leier, Hans C.; Bramer, Lisa M.; Weinstein, Jules B.; Bates, Timothy A.; Lee, Joon-Yong; Metz, Thomas O.; Schultz, Carsten; Tafesse, Fikadu G. A comprehensive...- SNT Gatchaman
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- ceramide covid 19 lipid droplets lipidomics lipids plasmalogen sphingomyelin
- Replies: 2
- Forum: Epidemics (including Covid-19, not Long Covid)
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Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity & Early Mortality Prediction,2023,Lodge
Integrative Plasma Metabolic and Lipidomic Modelling of SARS-CoV-2 Infection in Relation to Clinical Severity and Early Mortality Prediction Lodge, Samantha; Lawler, Nathan G.; Gray, Nicola; Masuda, Reika; Nitschke, Philipp; Whiley, Luke; Bong, Sze-How; Yeap, Bu B.; Dwivedi, Girish; Spraul...- SNT Gatchaman
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- ceramide kynurenine lipidomics lipids long covid mortality nicholson sphingolipids
- Replies: 1
- Forum: Long Covid research
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Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL, 2023, MOON et al.
Metabolomic Signatures of Sedentary Behavior and Cardiometabolic Traits in US Hispanics/Latinos: Results from HCHS/SOL Moon, Jee-Young;Chai, Jin Choul;Yu, Bing;Song, Rebecca J.;Chen, Guo-Chong;Graff, Mariaelisa;Daviglus, Martha L.;Chan, Queenie;Thyagarajan, Bharat;Castaneda, Sheila F.;Grove...- SNT Gatchaman
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- amino acids deconditioning diabetes exercise hypertension lipids plasmalogen sedentary
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- Forum: Other health news and research
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Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle, 2022, McNally et al.
Long-chain ceramides are cell non-autonomous signals linking lipotoxicity to endoplasmic reticulum stress in skeletal muscle McNally, Ben D.; Ashley, Dean F.; Hänschke, Lea; Daou, Hélène N.; Watt, Nicole T.; Murfitt, Steven A.; MacCannell, Amanda D. V.; Whitehead, Anna; Bowen, T. Scott; Sanders...- SNT Gatchaman
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- ceramide endoplasmic reticulum er stress extracellular vesicles lipids lipotoxicity perk upr
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- Forum: Other health news and research
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Preprint Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis, 2023, Li et al.
Unveiling the Intercompartmental Signaling Axis: Mitochondrial to ER Stress Response MERSR and its Impact on Proteostasis Jeson J Li; Nan Xin; Chunxia Yang; Larrisa A Tavizon; Ruth Hong; Travis I Moore; Rebecca G Tharyan; Adam Antebi; Hyun-Eui Kim Maintaining protein homeostasis is essential...- SNT Gatchaman
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- ceramide eif2a endoplasmic reticulum er stress hsp70 lipids mitochondria mortilin perk upr
- Replies: 8
- Forum: Other health news and research
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Hypothesis Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome, 2023, Sousa et al.
Attenuation of ferroptosis as a potential therapeutic target for neuropsychiatric manifestations of post-COVID syndrome Sousa, Ricardo A. L.; Yehia, Asmaa; Abulseoud, Osama A. Coronavirus disease-19 (COVID-19), caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), is...- SNT Gatchaman
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- cognitive dysfunction covid ferritin ferroptosis gpx4 immune dysfunction inflammation iron lipids long covid myelin neuropsychiatric disorders
- Replies: 0
- Forum: Long Covid research
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A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy, 2023, Southwell et al.
A coordinated multiorgan metabolic response contributes to human mitochondrial myopathy Nneka Southwell; Guido Primiano; Viraj Nadkarni; Nabeel Attarwala; Emelie Beattie; Dawson Miller; Sumaitaah Alam; Irene Liparulo; Yevgeniya I Shurubor; Maria Lucia Valentino; Valerio Carelli; Serenella...- SNT Gatchaman
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- amino acids atf4 fatty acid oxidation fgf21 gdf15 integrated stress response lipid droplets lipids mitochondria mtor muscle myopathy tca cycle
- Replies: 4
- Forum: Other health news and research
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The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity, 2015, Heinz et al.
The Lipid-Modifying Enzyme SMPDL3B Negatively Regulates Innate Immunity Heinz; Baumann; Köberlin; Snijder; Gawish; Shui; Sharif; Aspalter; Müller; Kandasamy; Breitwieser; Pichlmair; Bruckner; Rebsamen; Blüml; Karonitsch; Fauster; Colinge; Bennett; Knapp; Superti-Furga Lipid metabolism and...- SNT Gatchaman
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- immune system innate immune system lipids macrophages smpdl3b sphingomyelin tlr-4
- Replies: 2
- Forum: Other health news and research
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Preprint Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms, 2023, Romenskaja et al.
Extracellular vesicles promote autophagy in human microglia through lipid raft-dependent mechanisms Diana Romenskaja; Ugne Jonavice; Augustas Pivoriunas Autophagy dysfunction has been closely related with pathogenesis of many neurodegenerative diseases and therefore represents a potential...- SNT Gatchaman
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- autophagy extracellular vesicles lipid rafts lipids microglia tlr-4
- Replies: 2
- Forum: Other health news and research
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Associations of circulating metabolites with cerebral white matter hyperintensities, 2023, Sun et al.
Associations of circulating metabolites with cerebral white matter hyperintensities Yan Sun; Yu Guo; Hong-Qi Li; Lan Tan; Jian-Feng Feng; Wei Cheng; Jin-Tai Yu White matter hyperintensities (WMH) are the most compelling risk factors of stroke, dementia, and early mortality. We aimed to...- SNT Gatchaman
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- brain fatty acids lipids mri white matter
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- Forum: Other health news and research
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High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner, 2023, Correa et al.
High-Density Lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner Correa; Del Giudice; Waldie; Thépaut; Micciula; Gerelli; Moulin; Delaunay; Fieschi; Pichler; Haertlein; Forsyth; Le Brun; Moir; Russell; Darwish; Brinck; Wodaje; Jansen; Martín...- SNT Gatchaman
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- cholesterol hdl lipids sars-cov-2 spike protein
- Replies: 2
- Forum: Epidemics (including Covid-19, not Long Covid)
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Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following (...), 2023, Achleitner et al
Full title: Clinical improvement of Long-COVID is associated with reduction in autoantibodies, lipids, and inflammation following therapeutic apheresis Abstract In the aftermath of the COVID-19 pandemic, we are witnessing an unprecedented wave of post-infectious complications. Most...- Wyva
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- 2023 apheresis autoantibodies inflammation lipids long covid paper study
- Replies: 2
- Forum: Long Covid research
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Metabolic features of chronic fatigue syndrome 2016 Naviaux et al
Significance Chronic fatigue syndrome is a multisystem disease that causes long-term pain and disability. It is difficult to diagnose because of its protean symptoms and the lack of a diagnostic laboratory test. We report that targeted, broad-spectrum metabolomics of plasma not only revealed a...- Andy
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- amino acids lipids mitochondria sphingolipids
- Replies: 1
- Forum: ME/CFS research
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Untargeted analysis in post-COVID-19 patients reveals dysregulated lipid pathways two years after recovery 2023 López-Hernández et al
Introduction: Similar to what it has been reported with preceding viral epidemics (such as MERS, SARS, or influenza), SARS-CoV-2 infection is also affecting the human immunometabolism with long-term consequences. Even with underreporting, an accumulated of almost 650 million people have been...- Andy
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- lipids mexico phosphatidylcholine phospholipids sphingomyelin
- Replies: 6
- Forum: Long Covid research