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hypothesis

  1. TamaraRC
    Thread

    ME Hypothesis- Noradrenergic Neuron Dysfunction

    Hello I have been working on an ME Hypothesis for the last few years. It describes three types of noradrenergic neuron dysfunction, two of which...
    Thread by: TamaraRC, Sep 20, 2024, 54 replies, in forum: ME/CFS research news
  2. FStevenChalmers
    Thread

    Heresy / Conjecture on the nature of PEM PESE PENE

    New here. An ME blogger suggested I bring this idea here for discussion. Will leave out 9/10ths of this idea, looking to see if there's interest...
    Thread by: FStevenChalmers, Aug 25, 2024, 35 replies, in forum: General ME/CFS discussion
  3. rvallee
    Thread

    What are the necessary conditions and criteria for a theoretical model of ME/CFS?

    Something I've been meaning to work out for a while. For any theoretical model explaining the mechanisms of ME/CFS, there are necessary conditions...
    Thread by: rvallee, May 4, 2024, 127 replies, in forum: General ME/CFS discussion
  4. Wyva
    Thread

    Hypothesis Patient-Generated Hypotheses Journal by the Patient-Led Research Collaborative

    "About the Patient-Generated Hypotheses Journal Welcome to the Patient-Led Research Collaborative’s first issue of the Patient-Generated...
    Thread by: Wyva, May 30, 2023, 1 replies, in forum: Long Covid research
  5. Jaybee00
    Thread

    Emotion regulation and the salience network: a hypothetical integrative model of fibromyalgia, Margarida Pinto et al 2022

    https://www.nature.com/articles/s41584-022-00873-6 Fibromyalgia is characterized by widespread pain, fatigue, sleep disturbances and other...
    Thread by: Jaybee00, Dec 26, 2022, 16 replies, in forum: Other psychosomatic news and research
  6. Sly Saint
    Thread

    Orthostatic Intolerance after COVID-19 Infection: Is Disturbed Microcirculation of the Vasa Vasorum of Capacitance Vessels... 2022, Wirth and Lohn

    Orthostatic Intolerance after COVID-19 Infection: Is Disturbed Microcirculation of the Vasa Vasorum of Capacitance Vessels the Primary Defect?...
    Thread by: Sly Saint, Dec 8, 2022, 18 replies, in forum: Long Covid research
  7. Creekside
    Thread

    The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure, 2022, Renz-Polster et al

    https://osf.io/ef3n4/ The newsbrief posting reminded me that this paper wasn't mentioned. I think it may be a pretty important hypothesis for...
    Thread by: Creekside, Feb 6, 2022, 53 replies, in forum: ME/CFS research
  8. MSEsperanza
    Thread

    The biological challenge of myalgic encephalomyelitis/chronic fatigue syndrome: a solvable problem (2016), Edwards, JC et al

    Edwards JC, McGrath S, Baldwin A, Livingstone M, Kewley A. The biological challenge of myalgic encephalomyelitis/chronic fatigue syndrome: a...
    Thread by: MSEsperanza, Mar 26, 2022, 30 replies, in forum: ME/CFS research
  9. Trish
    Thread

    Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/Chronic Fatigue Syndrome, 2021, Stanculescu, Bergquist et al.

    Lessons From Heat Stroke for Understanding Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Dominic Stanculescu, Nuno Sepúlveda, Chin Leong...
    Thread by: Trish, Dec 15, 2021, 9 replies, in forum: ME/CFS research
  10. SNT Gatchaman
    Thread

    An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome, Wirth et al, 2021

    An attempt to explain the neurological symptoms of Myalgic Encephalomyelitis/ Chronic Fatigue Syndrome Klaus J. Wirth, Carmen Scheibenbogen and...
    Thread by: SNT Gatchaman, Nov 23, 2021, 5 replies, in forum: ME/CFS research
  11. alex3619
    Thread

    The IDO2 tryptophan trap hypothesis

    There are some issues and concerns around the IDO2 tryptophan trap hypothesis about ME. These are my current thought directions, and should not be...
    Thread by: alex3619, Jun 14, 2021, 7 replies, in forum: ME/CFS research news
  12. Hoopoe
    Thread

    The symptoms of chronic fatigue syndrome are related to abnormal ion channel function (2000) Chaudhuri et al

    The pathogenesis of chronic fatigue syndrome (CFS) is unknown but one of the most characteristic features of the illness is fluctuation in...
    Thread by: Hoopoe, Feb 27, 2021, 1 replies, in forum: ME/CFS research
  13. Dolphin
    Thread

    Why are assumptions passed off as established knowledge?, 2020, Weisman et al

    https://www.sciencedirect.com/science/article/abs/pii/S0306987720302437 Medical Hypotheses Available online 24 March 2020, 109693 In Press,...
    Thread by: Dolphin, Mar 28, 2020, 12 replies, in forum: Other psychosomatic news and research
  14. Snowdrop
    Thread

    Vox article--Why your desk job is so damned exhausting (2019 update)

    https://www.vox.com/science-and-health/2018/9/5/17818170/work-fatigue-exhaustion-psychology "This is the greatest mystery of my adult life: How...
    Thread by: Snowdrop, Feb 8, 2019, 5 replies, in forum: Other health news and research
  15. Milo
    Thread

    The link between idiopathic intracranial hypertension, fibromyalgia, and CFS: exploration of a shared pathophysiology (2018) Hulens et al.

    The link between idiopathic intracranial hypertension, fibromyalgia, and chronic fatigue syndrome: exploration of a shared pathophysiology (This...
    Thread by: Milo, Dec 24, 2018, 3 replies, in forum: ME/CFS research
  16. Andy
    Thread

    How chronic administration of benzodiazepines leads to unexplained chronic illnesses: A hypothesis, 2018, LaCorte

    Abstract It is thought that an ill defined biochemical cascade may lead to protracted withdrawal symptoms subsequent to discontinuance of routine...
    Thread by: Andy, Jul 28, 2018, 6 replies, in forum: ME/CFS research
  17. Eagles
    Thread

    OMF-funded research: a metabolic ‘trap’ hypothesis for ME/CFS - Dr. Robert Phair, March 2018

    OMF-funded research: a metabolic ‘trap’ hypothesis for ME/CFS - Dr. Robert Phair, March 2018...
    Thread by: Eagles, Mar 14, 2018, 1 replies, in forum: ME/CFS research
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