glucose

Highlights Mononuclear cells are primary drivers of the exercise response in skeletal muscle • Release of histamine from skeletal muscle during exercise from mast cells • Histamine receptor antagonists impair post-exercise muscle glycogen resynthesis • Exercise-induced transcriptional...

Association of glycemic control with Long COVID in patients with type 2 diabetes: findings from the National COVID Cohort Collaborative N3C Samuel Soff, Yun Jae Yoo, Carolyn Bramante, Jane E B Reusch, Jared Davis Huling, Margaret A Hall, Daniel Brannock, Til Sturmer, Zachary Butzin-Dozier...

Disclosure: Question relates to my daughter, who has been tentatively diagnosed with OCHOS, orthostatic cerebral hypoperfusion syndrome. I hope folks won't mind me asking a question for personal reasons. Assuming a reduction in blood flow to the brain of about 25% (average quoted in Peter...

After the really interesting recent study by @Chris Ponting showing some markers of insulin resistance in ME patients, the question arises, why would the HbA1c not be indicating insulin resistance in these patients? I have seen Continuous Glucose Monitor (CGM) charts of people with ME, and...

I bought a continuous glucose monitor a while ago thinking it could be interesting to try. @TamaraRC 's post has inspired to me to finally put it on. Here's a trace from when I had 5 pieces of a medium pizza yesterday evening (peak on the right): and a relative of mine eating exactly the...

Revealing the Hidden Impacts: Insights into Biological Aging and Long-Term Effects in Pauci- and Asymptomatic COVID-19 Healthcare Workers Campisi, Manuela; Cannella, Luana; Bordin, Anna; Moretto, Angelo; Scapellato, Maria Luisa; Mason, Paola; Liviero, Filippo; Pavanello, Sofia; on behalf of...

Importance of Blood Glucose Measurement for Predicting the Prognosis of Long COVID: A Retrospective Study in Japan Yokoyama, Sho; Honda, Hiroyuki; Otsuka, Yuki; Tokumasu, Kazuki; Nakano, Yasuhiro; Sakurada, Yasue; Matsuda, Yui; Sunada, Naruhiko; Hasegawa, Toru; Takase, Ryosuke; Omura, Daisuke...

Frontal-striatal glucose metabolism and fatigue in patients with multiple sclerosis, long COVID, and COVID-19 recovered controls Rudroff, Thorsten This study compared brain glucose metabolism using FDG-PET in the caudate nucleus, putamen, globus pallidus, thalamus, and dorsolateral prefrontal...

miR-29a-3p, a new myokine orchestrating resistance exercise via coordinated metabolic responses Paola Pinto-Hernandez; Manuel Fernandez-Sanjurjo; Daan Paget; Xurde M Caravia; David Roiz-Valle; Juan Castilla-Silgado; Sergio Diez-Robles; Almudena Coto-Vilcapoma; Pau Gama; Pablo M Garcia-Roves...

Brain fog in long COVID: A glutamatergic hypothesis with astrocyte dysfunction accounting for brain PET glucose hypometabolism Abstract Brain [18F]FDG-PET scans have revealed a glucose hypometabolic pattern in patients with long COVID. This hypometabolism might reflect primary astrocyte...

Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...

Neurovascular coupling is the concept that in the CNS, organ function is tightly associated with blood flow, moreso than in other organs. Theoretical background and latest thinking — From the introduction in The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in...

Background Rapid fluid delivery from ingested beverages is the goal of oral rehydration solutions (ORS) and sports drinks. Objective The aim of the present study was to investigate the effects of increasing carbohydrate and sodium content upon fluid delivery using a deuterium oxide (D2O)...

Edit: Paper now published Post with abstract here. Outpatient Treatment of COVID-19 and the Development of Long COVID Over 10 Months: A Multi-Center, Quadruple-Blind, Parallel Group Randomized Phase 3 Trial Link (Open access to full paper) ************** Preprint abstract Outpatient...

Hallmarks of Metabolic Reprogramming and Their Role in Viral Pathogenesis Allen CNS, Arjona SP, Santerre M, Sawaya BE Metabolic reprogramming is a hallmark of cancer and has proven to be critical in viral infections. Metabolic reprogramming provides the cell with energy and biomass for...

Small-Molecule Inhibition of Glucose Transporters GLUT-1-4 Elena S Reckzeh, Herbert Waldmann Glucose addiction is observed in cancer and other diseases that are associated with hyperproliferation. The development of compounds that restrict glucose supply and decrease glycolysis has great...

FGF21 induces PGC-1⍺ and regulates carbohydrate and fatty acid metabolism during the adaptive starvation response Matthew J. Potthoff, Takeshi Inagaki, Santhosh Satapati, Xunshan Ding, Tianteng He, Regina Goetz, Moosa Mohammadi, Brian N. Finck, David J. Mangelsdorf, Steven A. Kliewer, Shawn C...

The Nuanced Metabolic Functions of Endogenous FGF21 Depend on the Nature of the Stimulus, Tissue Source, and Experimental Model Redin A. Spann, Christopher D. Morrison and Laura J. den Hartigh Fibroblast growth factor 21 (FGF21) is a hormone that is involved in the regulation of lipid, glucose...

Going Back to the Biology of FGF21: New Insights Jo E. Lewis, Francis J.P. Ebling, Ricardo J. Samms, Kostas Tsintzas Fibroblast growth factor 21 (FGF21) is a protein highly synthesized in the liver that exerts paracrine and endocrine control of many aspects of energy homeostasis in multiple...

Understanding the Physiology of FGF21 Ffolliott Martin Fisher and Eleftheria Maratos-Flier Fibroblast growth factor 21 (FGF21) is a peptide hormone that is synthesized by several organs and regulates energy homeostasis. Excitement surrounding this relatively recently identified hormone is based...