epigenetics

  1. Andy

    Review DNA methylation signatures of functional somatic syndromes: Systematic review, 2023, Fischer et al

    Objective Functional somatic syndromes (FSS) are highly prevalent across all levels of healthcare. The fact that they are characterised by medically unexplained symptoms, such as fatigue and pain, raises the important question of their underlying pathophysiology. Psychosocial stress represents...
    • Andy
    • Thread
    • dna methylation epigenetics hdac hla hla-dqb1
    • Replies: 5
    • Forum: ME/CFS research
  2. SNT Gatchaman

    DNA methylation dynamics associated with long-term isolation of simulated space travel, 2022, Hou et al.

    DNA methylation dynamics associated with long-term isolation of simulated space travel Fei Hou; Xu Zhou; Shunheng Zhou; Haizhou Liu; Yu-e Huang; Mengqin Yuan; Jicun Zhu; Xinyu Cao; Wei Jiang Long-term isolation is one of the risk factors that astronauts will encounter in spaceflight. At present...
  3. SNT Gatchaman

    Metabolic regulation of gene expression by histone lactylation, 2019, Zhang et al.

    Metabolic regulation of gene expression by histone lactylation Zhang, Di; Tang, Zhanyun; Huang, He; Zhou, Guolin; Cui, Chang; Weng, Yejing; Liu, Wenchao; Kim, Sunjoo; Lee, Sangkyu; Perez-Neut, Mathew; Ding, Jun; Czyz, Daniel; Hu, Rong; Ye, Zhen; He, Maomao; Zheng, Y. George; Shuman, Howard A...
  4. SNT Gatchaman

    Review Viral miRNA regulation of host gene expression, 2023, Diggins and Hancock

    Viral miRNA regulation of host gene expression Diggins; Hancock Viruses have evolved a multitude of mechanisms to combat barriers to productive infection in the host cell. Virally-encoded miRNAs are one such means to regulate host gene expression in ways that benefit the virus lifecycle. miRNAs...
  5. SNT Gatchaman

    Preprint Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures, 2023, Wang et al.

    Human Immune Cell Epigenomic Signatures in Response to Infectious Diseases and Chemical Exposures Wenliang Wang; Manoj Hariharan; Anna Bartlett; Cesar Barragan; Rosa Castanon; Vince Rothenberg; Haili Song; Joseph Nery; Andrew Aldridge; Jordan Altshul; Mia Kenworthy; Wubin Ding; Hanqing Liu; Wei...
    • SNT Gatchaman
    • Thread
    • chemical exposure dna dna methylation epigenetics epigenomics immune cells immune system infection methylation pbmc single-cell genomics
    • Replies: 6
    • Forum: Other health news and research
  6. rvallee

    Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study, 2023, Pariante et el

    Higher immune-related gene expression in major depression is independent of CRP levels: results from the BIODEP study https://www.nature.com/articles/s41398-023-02438-x Abstract (paragraphs mine) Compelling evidence demonstrates that some individuals suffering from major depressive disorder...
  7. Kalliope

    Preprint Medrix: Dynamic Epigenetic Changes during a Relapse and Recovery Cycle in ME/CFS - Helliwell, Tate et al -2022

    Preprint Medrix Dynamic Epigenetic Changes during a Relapse and Recovery Cycle in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Helliwell A.M., Stockwell P.A., Edgar C.D., Chatterjee A., & Tate W.P. Abstract (242) Background Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is...
  8. John Mac

    Open The Influence of Epigenetic Modifications and Post-Exertional Malaise in People With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome 2021 Polli

    Not yet recruiting https://www.medifind.com/conditions/chronic-fatigue-syndrome/1135/clinical-trial/223304133
  9. Sly Saint

    Recursive ensemble feature selection provides a robust mRNA expression signature for ME/CFS, 2021, Metselaar et al

    Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome https://www.nature.com/articles/s41598-021-83660-9
    • Sly Saint
    • Thread
    • 2021 biomarker epigenetics me/cfs methylation metselaar mrna netherlands paper
    • Replies: 19
    • Forum: ME/CFS research
  10. John Mac

    Changes in DNA methylation profiles of myalgic encephalomyelitis/chronic fatigue syndrome patients reflect systemic dysfunctions, Helliwell et al 2020

    https://clinicalepigeneticsjournal.biomedcentral.com/articles/10.1186/s13148-020-00960-z
    • John Mac
    • Thread
    • dna epigenetics helliwell me/cfs methylation new zealand sweetman tate
    • Replies: 10
    • Forum: ME/CFS research
  11. Andy

    DNA methylation and BDNF expression account for symptoms and widespread hyperalgesia in patients with CFS and Fibromyalgia, 2020, Polli et al

    Paywall, https://onlinelibrary.wiley.com/doi/abs/10.1002/art.41405 Sci hub, https://sci-hub.tw/10.1002/art.41405 Funded by ME Research UK. Fukuda selection criteria.
    • Andy
    • Thread
    • 2020 bdnf epigenetics fibromyalgia me/cfs meruk paper polli
    • Replies: 12
    • Forum: ME/CFS research
  12. H

    Epigenetic Modifications and Glucocorticoid Sensitivity in ME/CFS, 2017, de Vega, Vernon et al

    This study by Wilfred De Vega et. al. has been discussed before on the forums, I think, but here it is again https://pubmed.ncbi.nlm.nih.gov/28231836/ . 2017 Feb 23;10(1):11. doi: 10.1186/s12920-017-0248-3. Epigenetic Modifications and Glucocorticoid Sensitivity in Myalgic...
    • Helen
    • Thread
    • 2017 cortisol de vega epigenetics me/cfs methylation paper vernon
    • Replies: 2
    • Forum: ME/CFS research
  13. Dolphin

    Changes in the Epigenetic Landscape of ME/CFS Reflect Systemic Dysfunctions; Helliwell, Thesis 2019, paper 2020

  14. J

    Reversing age: dual species measurement of epigenetic age with a single clock

    https://www.biorxiv.org/content/10.1101/2020.05.07.082917v1 Preprint twitter thread here
  15. Sly Saint

    Open Epigenetics of Post-exertional Malaise in Patients With ME/CFS: Oct 2020 [This trial is not yet open for recruitment]

    Sponsor Vrije Universiteit Brussel Overall contact Andrea Polli, MSc full details here: https://www.smartpatients.com/trials/NCT04378634
  16. D

    Reversing Ageing: New Studies Show it Can be Done

    Sounds too good to be true.
  17. MeSci

    Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk, 2019, Zannas et al.

    Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB–driven inflammation and cardiovascular risk Anthony S. Zannas,a,b,c,d,1 Meiwen Jia,a Kathrin Hafner,a Jens Baumert,e Tobias Wiechmann,a Julius C. Pape,a Janine Arloth,a,f Maik Ködel,a Silvia Martinelli,a Maria Roitman,a...
  18. M

    Alterations in DNA Methylation Status Associated with Gulf War Illness (2019) Trivedi et al

    Alterations in DNA Methylation Status Associated with Gulf War Illness https://www.liebertpub.com/doi/full/10.1089/dna.2018.4469 This is Dr Klimas’ group- paywalled. Abstract Gulf War Illness (GWI) affects about 25% of Persian Gulf veterans with a cluster of chronic symptoms, including...
  19. Sly Saint

    Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns, 2018, Trivedi, Klimas et al

    Public on Jul 23, 2018 https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE111183 eta: It's an article in PLOSone Published: July 23, 2018 https://doi.org/10.1371/journal.pone.0201066 full study here: http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0201066
    • Sly Saint
    • Thread
    • 2018 epigenetics genomics immunology klimas me/cfs methylation paper
    • Replies: 2
    • Forum: ME/CFS research
  20. Sasha

    Oltra et al.: Effect of ME/CFS on epigenetic regulation in specific immune cell types (grant)

    Another Solve grantee: http://solvecfs.org/2017-ramsay-award-program-team-2/
    • Sasha
    • Thread
    • epigenetics oltra solve mecfs initiative
    • Replies: 1
    • Forum: ME/CFS research
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