epigenetics

  1. Nightsong

    Preprint Comparing DNA Methylation Landscapes in Peripheral Blood from [ME/CFS] and Long COVID Patients, 2025, Peppercorn et al

    Abstract Post-viral conditions, Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and Long COVID (LC), share >95% of their symptoms, but the connection between disturbances in their underlying molecular biology is unclear. This study investigates DNA methylation patterns in peripheral...
  2. Wyva

    Associations of epigenetic aging and COVID- 19: A 3-year longitudinal study, 2025, Farkas et al

    Abstract Aging and COVID- 19 are known to influence DNA methylation, potentially affecting the rate of aging and the risk of disease. The physiological functions of 54 volunteers—including maximal oxygen uptake (VO₂ max), grip strength, and vertical jump—were assessed just before the COVID- 19...
  3. SNT Gatchaman

    Synchronized long-read genome, methylome, epigenome and transcriptome profiling resolve a Mendelian condition, 2025, Vollger et al.

    Synchronized long-read genome, methylome, epigenome and transcriptome profiling resolve a Mendelian condition Vollger, Mitchell R.; Korlach, Jonas; Eldred, Kiara C.; Swanson, Elliott; Underwood, Jason G.; Bohaczuk, Stephanie C.; Mao, Yizi; Cheng, Yong-Han H.; Ranchalis, Jane; Blue, Elizabeth E...
  4. SNT Gatchaman

    Exploring common pathogenic association between [EBV] and [LC] by integrating RNA-Seq and molecular dynamics simulations, 2024, Kanwal+Zhang

    Exploring common pathogenic association between Epstein Barr virus infection and long-COVID by integrating RNA-Seq and molecular dynamics simulations Kanwal, Ayesha; Zhang, Zhiyong The term "Long-COVID" (LC) is characterized by the aftereffects of COVID-19 infection. Various studies have...
  5. SNT Gatchaman

    Spaceflight alters host-gut microbiota interactions, 2024, Gonzalez et al.

    Spaceflight alters host-gut microbiota interactions Gonzalez, E.; Lee, M. D.; Tierney, B. T.; Lipieta, N.; Flores, P.; Mishra, M.; Beckett, L.; Finkelstein, A.; Mo, A.; Walton, P.; Karouia, F.; Barker, R.; Jansen, R. J.; Green, S. J.; Weging, S.; Kelliher, J.; Singh, N. K.; Bezdan, D.; Galazska...
  6. Mij

    Epigenetic patterns, accelerated biological aging, and enhanced epigenetic drift detected 6 months following C-19 infection: genome-wide DNA study

    Epigenetic patterns, accelerated biological aging, and enhanced epigenetic: drift detected 6 months following COVID-19 infection: insights from a genome-wide DNA methylation study, 2024, Calzari Luciano, Dragani Davide Fernando et al Abstract Background The epigenetic status of patients 6-month...
    • Mij
    • Thread
    • apoptosis endothelin epigenetics glutamate glutamine hif-1 insulin t cells vegf
    • Replies: 0
    • Forum: Long Covid research
  7. SNT Gatchaman

    Revealing the Hidden Impacts: Insights into Biological Aging & Long-Term Effects in Pauci- & Asymptomatic COVID-19 Healthcare Workers, 2024, Campisi+

    Revealing the Hidden Impacts: Insights into Biological Aging and Long-Term Effects in Pauci- and Asymptomatic COVID-19 Healthcare Workers Campisi, Manuela; Cannella, Luana; Bordin, Anna; Moretto, Angelo; Scapellato, Maria Luisa; Mason, Paola; Liviero, Filippo; Pavanello, Sofia; on behalf of...
  8. SNT Gatchaman

    Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome, 2024, Maiti, Amit K.

    Bioinformatic analysis predicts the regulatory function of noncoding SNPs associated with Long COVID-19 syndrome Maiti, Amit K. Long or Post COVID-19 is a condition of collected symptoms persisted after recovery from COVID-19. Host genetic factors play a crucial role in developing Long...
  9. SNT Gatchaman

    Blood DNA methylation in post-acute sequelae of COVID-19 PASC: a prospective cohort study, 2024, Balnis et al.

    Blood DNA methylation in post-acute sequelae of COVID-19 PASC: a prospective cohort study Joseph Balnis; Andy Madrid; Lisa A. Drake; Rachel Vancavage; Anupama Tiwari; Vraj J. Patel; Ramon Bossardi Ramos; John J. Schwarz; Recai Yucel; Harold A. Singer; Reid S. Alisch; Ariel Jaitovich BACKGROUND...
  10. SNT Gatchaman

    Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop [LC], 2024, Biondi+

    Differential Gene Expression in the Upper Respiratory Tract following Acute COVID-19 Infection in Ambulatory Patients That Develop Long COVID Biondi, Mia J.; Addo, Mary; Zahoor, Muhammad Atif; Salvant, Elsa; Yip, Paul; Barber, Bethany; Smookler, David; Wasif, Sumaiyah; Gaete, Kayla; Kandel...
    • SNT Gatchaman
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    • coagulation complement cpb2 epigenetics fibrinogen fibrinolysis il-7 kallikreins transcriptomics
    • Replies: 9
    • Forum: Long Covid research
  11. SNT Gatchaman

    Review SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19, 2024, Guarnieri et al.

    SARS-CoV-2 Mitochondrial Metabolic and Epigenomic Reprogramming in COVID-19 Guarnieri; Haltom; Albrecht; Lie; Olali; Widjaja; Ranshing; Angelin; Murdock; Wallace To determine the effects of SARS-CoV-2 infection on cellular metabolism, we conducted an exhaustive survey of the cellular metabolic...
    • SNT Gatchaman
    • Thread
    • atf6 cgas-sting epigenetics fgf21 gdf15 glycolysis hif-1 histone innate immune system integrated stress response interferon metabolic reprogramming metabolism mitochondria oxidative phosphorylation pentose phospate pathway perk tlr-9 upr
    • Replies: 2
    • Forum: Long Covid research
  12. leokitten

    Tissue-specific enhancer–gene maps from multimodal single-cell data identify causal disease alleles, 2024, Sakaue et al

    https://www.nature.com/articles/s41588-024-01682-1 Medical Xpress: Researchers develop statistical method for genetic mapping of autoimmune diseases Wondering if something like this could help Decode ME
  13. SNT Gatchaman

    Review [ME/CFS] from current evidence to new diagnostic perspectives through skeletal muscle and metabolic disturbances, 2024, Pietrangelo et al.

    Myalgic encephalomyelitis/chronic fatigue syndrome from current evidence to new diagnostic perspectives through skeletal muscle and metabolic disturbances Tiziana Pietrangelo; Stefano Cagnin; Danilo Bondi; Carmen Santangelo; Lorenzo Marramiero; Cristina Purcaro; Raphael Severino Bonadio; Ester...
  14. SNT Gatchaman

    Review Defining trained immunity and its role in health and disease, 2020, Netea et al.

    Defining trained immunity and its role in health and disease Netea, Mihai G.; Domínguez-Andrés, Jorge; Barreiro, Luis B.; Chavakis, Triantafyllos; Divangahi, Maziar; Fuchs, Elaine; Joosten, Leo A. B.; van der Meer, Jos W. M.; Mhlanga, Musa M.; Mulder, Willem J. M.; Riksen, Niels P.; Schlitzer...
  15. SNT Gatchaman

    Preprint BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III, 2024, Chen et al

    BRD4-mediated epigenetic regulation of endoplasmic reticulum-mitochondria contact sites is governed by the mitochondrial complex III Brandon Chen; Theophilus M Lynn-Nguyen; Pankaj Jadhav; Benjamin S Halligan; Nicholas J Rossiter; Rachel M Guerra; Sergei Koshkin; Imhoi Koo; Pietro Morlacchi...
    • SNT Gatchaman
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    • brd4 complex 3 endoplasmic reticulum epigenetics hif-1 hypoxia integrated stress response jak inhibitors jak-stat mitochondria mitochondrial dynamics perk
    • Replies: 0
    • Forum: Other health news and research
  16. SNT Gatchaman

    Preprint Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight, 2024, Sakharkar et al.

    Systemic Genome Correlation Loss as a Central Characteristic of Spaceflight Anurag Sakharkar; Kiven Erique Lukong; Lauren M Sanders; Sylvain V Costes; Jian Yang; Changiz Taghibiglou Space exploration has captured the imagination of humanity for generations. From the first steps on the moon to...
    • SNT Gatchaman
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    • collagen corticotropin epigenetics genes metabolomics mirna mitochondria mitochondrial dysfunction proteomics spaceflight transcriptomics vegf
    • Replies: 2
    • Forum: Other health news and research
  17. SNT Gatchaman

    Preprint Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications, 2023, Mikulski et al.

    Transcriptional memory is conferred by combined heritable maintenance and local removal of selective chromatin modifications Pawel Mikulski; Sahar S.H. Tehrani; Anna Kogan; Izma Abdul-Zani; Emer Shell; Brent J Ryan; Lars E.T. Jansen Interferon-γ (IFNγ) transiently activates genes involved in...
  18. SNT Gatchaman

    Preprint Linking the gut microbiome to host DNA methylation by a discovery and replication epigenome-wide association study, 2023, Demirkan et al.

    Linking the gut microbiome to host DNA methylation by a discovery and replication epigenome-wide association study Ayse Demirkan; Jenny van Dongen; Casey Finnicum; Harm Jan Westra; Soesma Jankipersadsing; Gonneke Willemsen; Richard Ijzerman; Dorret Boomsma; Erik Ehli; Mark Jan Bonder; Jingyuan...
  19. SNT Gatchaman

    Review Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19, 2023, Nair et al.

    Genomic communication via circulating extracellular vesicles and long-term health consequences of COVID-19 Nair, Soumyalekshmi; Nova-Lamperti, Estefania; Labarca, Gonzalo; Kulasinghe, Arutha; Short, Kirsty R.; Carrión, Flavio; Salomon, Carlos COVID-19 continues to affect an unprecedented number...
    • SNT Gatchaman
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    • epigenetics extracellular vesicles gene expression glucose innate immune system lipid metabolism long covid metabolism sars-cov-2 spike protein thrombosis
    • Replies: 0
    • Forum: Long Covid research
  20. SNT Gatchaman

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors, 2023, Cheong et al.

    Epigenetic memory of coronavirus infection in innate immune cells and their progenitors Jin-Gyu Cheong; Arjun Ravishankar; Siddhartha Sharma; Christopher N. Parkhurst; Simon A. Grassmann; Claire K. Wingert; Paoline Laurent; Sai Ma; Lucinda Paddock; Isabella C. Miranda; Emin Onur Karakaslar...
    • SNT Gatchaman
    • Thread
    • bone marrow covid-19 epigenetics haematopoietic stem cell progenitors hspc il-6 immune dysfunction innate immune system monocytes stem cells trained innate immunity
    • Replies: 6
    • Forum: Long Covid research
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