Patients with chronic fatigue syndrome performed worse than controls in a controlled repeated exercise study despite a normal oxidative phosphorylation capacity
Vermeulen, Ruud CW; Kurk, Ruud M; Visser, Frans C; Sluiter, Wim; Scholte, Hans R
Background
The aim of this study was to investigate...
Maximal oxidative capacity during exercise is associated with muscle power output in patients with long coronavirus disease 2019 COVID-19 syndrome. A moderation analysis
Robinson Ramírez-Vélez; Sergio Oscoz-Ochandorena; Yesenia García-Alonso; Nora García-Alonso; Gaizka Legarra-Gorgoñon; Julio...
UTILITY OF 2-DAY CARDIOPULMONARY EXERCISE TESTING PROTOCOL IN LONG-HAUL COVID (LHC) PATIENTS: PRELIMINARY DATA
Purpose: Long Haul COVID (LHC) patients have prominent symptoms of fatigue and exercise limitation. Comparisons have been made between Chronic Fatigue Syndrome/Myalgic...
This study found reduced oxygen extraction in the thigh muscles of people with ongoing symptoms after Covid-19 infections as compared to healthy controls:
Structural and functional impairments of skeletal muscle in patients with [PASC], 2023, Colosio et al.
The measure is "Δ[HHbMb]peak (%...
Abstract
Essential elements of Myalgic Encephalomyelitis (ME) are muscle (weakness) and tenderness, cognitive deficits, neurological impairments, especially of cognitive, autonomic and sensory functions, but above all, post-exertional “malaise”: a prolonged increase of symptoms after a minor...
Decreased physical performance despite objective and subjective maximal exhaustion in post-COVID-19 individuals with fatigue
Vollrath, Shirin; Matits, Lynn; Schellenberg, Jana; Kirsten, Johannes; Steinacker, Jürgen M.; Bizjak, Daniel A.
Introduction
Fatigue is a common symptom in post-COVID-19...
Reduced athletic performance post-COVID-19 is associated with reduced anaerobic threshold
Robert M Barker-Davies; Peter Ladlow; Rebecca Chamley; Edward Nicol; David A Holdsworth
Detailed characterisation of cardiopulmonary limitations in patients post-COVID-19 is currently limited, particularly...
"The value of clinical cardiopulmonary exercise testing (CPET) within healthcare settings has been established in the last decade. CPET methods remain highly relevant in the COVID-19 endemic phase and should be used to assess those recovering from COVID-19 infection.
This diagnostic tool could...
Abstract
Background: Cardiopulmonary exercise testing (CPET) has been suggested by the European Society of Cardiology (ESC) for assessing the exercise limitations of apparently healthy individuals, but data on elite athletes regarding this test are scarce.
Methods: We analyzed CPET in elite...
ME/CFS is a debilitating disease with obscure aetiology. However, despite the extensive amount of research that has been performed on the transcriptomes of ME/CFS patients, all of them are solely focused on linear RNAs, and the profiling of circRNAs in ME/CFS has been completely omitted. In this...
Highlights
Ours is one of the first CPET studies to highlight reduced O2 pulse peak % predicted (impaired oxygen extraction) as a mechanism of chronic fatigue and exercise intolerance in long COVID.
Our study identified chronotropic intolerance as a potential biomarker in long COVID.
We...
Abstract:
Background and Objectives: Post-exertional malaise (PEM) is the hallmark of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS), but there has been little effort to quantitate the duration of PEM symptoms following a known exertional stressor. Using a Symptom Severity Scale...
Abstract
Some survivors of humidifier disinfectants (HDs) complain of chronic, inexplicable fatigue, and post-exertional malaise (PEM). Two-day cardiopulmonary exercise tests (CPETs) performed 24 hours apart (2-day CPET protocol) are increasingly employed to evaluate PEM and related...
The Mechanism of Effort Intolerance in Patients with Peripheral Arterial Disease: a Combined Stress Echocardiography and Cardiopulmonary Exercise Test
Eihab Ghantous, Aviel Shetrit, Yonatan Erez, Ryan S. Zamanzadeh, David Zahler, Yoav Granot, Erez Levi, Michal Laufer Perl, Shmuel Banai, Yan...
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0277984
Introduction
After the acute Sars-CoV-2-infection, some athletes suffer from persistent, performance-impairing symptoms, although the course of the disease is often mild to moderate. The relation between cardiopulmonary...
Abstract
This study aimed to assess pulmonary and muscle dysfunction by analyzing the slow component of oxygen uptake (VO2SC), and mechanical and ventilatory efficiency in adult women recovered from the severe acute respiratory syndrome coronavirus type II (SARS-CoV-2) during a constant load...
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