covid 19

I think I have covid. I am not sure that I'm up to date on what should be done in this situation. Please advise. Symptoms started 3 days ago with a sore throat. Now a stuffy nose, cough with a little production of phlegm, and a bit of malaise. No worrying symptoms but I'm a little concerned...

Presence of SARS-CoV-2 in middle ear fluid and characterization of otitis media with effusion in COVID-19 patients Highlights The role of SARS-CoV-2 in OME is currently unknown. Eighteen out of 27 MEF specimens of COVID-19 group tested positive for SARS-CoV-2. The presence of SARS-CoV-2 in MEF...

Haunting innate immune memories of COVID-19 In addition to acute hyperinflammatory responses, SARS-CoV-2 infections can have long-term effects on our immune system leading to, for example, post-acute sequelae of COVID-19 (PASC). In this issue of Cell, Cheong et al. show that severe infections...

Dissecting human population variation in single-cell responses to SARS-CoV-2 Abstract Humans display substantial interindividual clinical variability after SARS-CoV-2 infection1,2,3, the genetic and immunological basis of which has begun to be deciphered4. However, the extent and drivers of...

Abstract Background Although COVID-19 is primarily an acute respiratory infection, 5%–40% of patients develop late and prolonged symptoms with frequent neurological complaints, known as long COVID syndrome. The presentation of the disease suggests that COVID infection may cause functional...

New Zealand's COVID-19 elimination strategy and mortality patterns Stacey Kung; Thomas Hills; Nethmi Kearns; Richard Beasley No Abstract Link | PDF (The Lancet)

If someone with ME has very positive reactions to COVID-19 vaccination, are they less likely to have a bad outcome from the actual virus? The Covid vaccine (I get the Moderna) gives me a bizarre side effect: A week of near remission from ME, including reduced severity/duration of PEM. I...

Psychiatric Symptoms in Acute and Persisting Forms of COVID-19 Associated with Neural Autoantibodies Hansen, Niels (1) Background: In this narrative review, we focus on neural autoantibodies in patients with coronavirus disease 2019 (COVID-19) as a consequence of severe acute respiratory...

SARS-CoV-2-specific T cell therapy for severe COVID-19: a randomized phase 1/2 trial Abstract Despite advances, few therapeutics have shown efficacy in severe coronavirus disease 2019 (COVID-19). In a different context, virus-specific T cells have proven safe and effective. We conducted a...

Functional characterisation of the ACE2 orthologues in Drosophila provides insights into the neuromuscular complications of COVID-19 Highlights A large percentage of patients with COVID-19 have neuromuscular manifestations. Loss of Drosophila ACE2 orthologues Ance or Ance3 impaired motoric...

Diabetes following SARS-CoV-2 infection: Incidence, persistence, and implications of COVID-19 vaccination. A cohort study of fifteen million people. Background Type 2 diabetes (T2DM) incidence is increased after diagnosis of COVID-19. The impact of vaccination on this increase, for how long...

Ivabradine effects on COVID-19-associated postural orthostatic tachycardia syndrome: a single center prospective study Background: A wide range of cardiac arrhythmias were reported in the setting of active infection or as a complication of COVID-19. The main pathophysiology can be attributed...

Differential effects of SARS-CoV-2 variants on central nervous system cells and blood–brain barrier functions Background Although mainly causing a respiratory syndrome, numerous neurological symptoms have been identified following of SARS-CoV-2 infection. However, how the virus affects the...

Abstract The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants of concern such as Omicron hampered efforts in controlling the ongoing coronavirus disease 2019 pandemic due to their ability to escape neutralizing antibodies induced by vaccination or prior...

Full title: The effects of COVID-19 on cognitive performance in a community-based cohort: a COVID symptom study biobank prospective cohort study Summary Background Cognitive impairment has been reported after many types of infection, including SARS-CoV-2. Whether deficits following SARS-CoV-2...