Note: cringe worthy, be warned.
Abstract
Stress has been demonstrated to be involved in the development of medically unexplained symptoms.
A key underlying mechanism could be lower levels of cortisol, which can contribute to symptoms such as fatigue or pain.
However, the literature is...
Self-soothing touch and being hugged reduce cortisol responses to stress: A randomized controlled trial on stress, physical touch, and social identity
Aljoscha Dreisoernera,*, Nina M. Junkera, Wolff Schlotza,b, Julia Heimricha, Svenja Bloemekec, Beate Ditzend, Rolf van Dicka
Abstract...
An old paper
Korszun, A., L. Sackett-Lundeen, E. Papadopoulos, C. Brucksch, L. Masterson, N. C. Engelberg, E. Haus, M. A. Demitrack, and L. Crofford. “Melatonin Levels in Women with Fibromyalgia and Chronic Fatigue Syndrome.” The Journal of Rheumatology 26, no. 12 (December 1999): 2675–80...
Full title: Assessment of cytokines, microRNA and patient related outcome measures in conversion disorder/functional neurological disorder (CD/FND): The CANDO clinical feasibility study
Highlights
• It is feasible to establish and assess a cohort of CD/FND with motor symptoms, involving...
Abstract
Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disease usually presenting after infection. Emerging evidence supports that energy metabolism is affected in ME/CFS, but a unifying metabolic phenotype has not been firmly established.
We performed global...
Abstract
Context
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a severe chronic illness which reduces the quality of life. A potential role of neuroendocrine autoimmune dysfunction has been hypothesized.
Objective
To investigate the occurrence of anti-pituitary (APA) and...
Nature - molecular psychiatry
Chronic post-COVID-19 syndrome and chronic fatigue syndrome: Is there a role for extracorporeal apheresis? - Bornstein et al
Abstract
As millions of patients have been infected by SARS-CoV-2 virus a vast number of individuals complain about continuing...
(Note that this is an old study from 2004)
Abstract
Context: There is no established pharmacological treatment for the core symptoms of chronic fatigue syndrome (CFS). Galantamine hydrobromide, an acetyl cholesterone inhibitor, has pharmacological properties that might benefit patients with...
Medscape: The Anxious History of Understanding Cortisol
Came across this on Medscape today and since we've been having discussions on what "stress" is elsewhere on the forum--to say nothing of the many discussions on cortisol and ME/CFS over many years--it seemed a bit interesting to see how...
Abstract
Psychosocial and socioeconomic adversity in early childhood (termed ‘social adversity’) can have lifelong detrimental effects on health and development.
Physiological stress is one proposed mechanism by which social adversity ‘gets under the skin’. There is substantial research...
https://www.researchgate.net/profile/Joshua_Leisk/publication/350043016_The_true_nature_of_an_autoimmune_disease/links/604d0d31a6fdcccfee7d03be/The-true-nature-of-an-autoimmune-disease.pdf?origin=publication_detail
Preprint—not peer reviewed.
Abstract
Here we propose a hypothetical model...
I have been reading a bit into the three cortisol studies that have been done in the 90’s.
I would like to discuss the ideas that come out of a critical evaluation of these studies.
A lot of it is stating the obvious in my mind, but I still think it’s worth discussing. How could we repeat these...
https://www.frontiersin.org/articles/10.3389/fmed.2021.628029/full?utm_source=F-NTF&utm_medium=EMLX&utm_campaign=PRD_FEOPS_20170000_ARTICLE
Here the hypothesis is advanced that maladaptive mechanisms that prevent recovery in some intensive care unit (ICU) patients may also underlie Myalgic...
This study by Wilfred De Vega et. al. has been discussed before on the forums, I think, but here it is again
https://pubmed.ncbi.nlm.nih.gov/28231836/
. 2017 Feb 23;10(1):11.
doi: 10.1186/s12920-017-0248-3.
Epigenetic Modifications and Glucocorticoid Sensitivity in Myalgic...
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