central nervous system

  1. forestglip

    Preprint Guardian angels off duty? ME/CFS is Sustained by an Impaired Stress Response in the Central Nervous System, 2024, Renz-Polster

    Guardian angels off duty? ME/CFS is Sustained by an Impaired Stress Response in the Central Nervous System Herbert Renz-Polster Abstract ME/CFS researchers agree that ME/CFS is a multisystem disease with a multitude of pathobiological features including endothelial dysfunction, immune...
  2. C

    The Pathobiology of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: The Case for Neuroglial Failure, 2022, Renz-Polster et al

    https://osf.io/ef3n4/ The newsbrief posting reminded me that this paper wasn't mentioned. I think it may be a pretty important hypothesis for ME's root cause. It fits what I believe is the root cause of ME: that neuroglia are involved. I'm not sure whether there are any ME symptoms that...
    • Creekside
    • Thread
    • astrocytes brain central nervous system cerebral blood flow cerebral hypoperfusion etiology glial cells hypothesis me/cfs microglia neurology
    • Replies: 53
    • Forum: ME/CFS research
  3. O

    The autoimmune aetiology of unexplained chronic pain, 2021, Goebel et al

    Abstract Chronic pain is the leading cause of life years lived with disability worldwide. The aetiology of most chronic pain conditions has remained poorly understood and there is a dearth of effective therapies. The WHO ICD-11 has categorised unexplained chronic pain states as ‘chronic primary...
  4. Mij

    OPTN is a host intrinsic restriction factor against neuroinvasive HSV-1 infection, 2021, Joshua Ames

    Abstract Fast-replicating neurotropic herpesviruses exemplified by herpes simplex virus-1 (HSV-1) naturally infect the central nervous system (CNS). However, most individuals intrinsically suppress the virus during a primary infection and preclude it from significantly damaging the CNS...
  5. Andy

    Increased Serological Response Against Human Herpesvirus 6A Is Associated With Risk for Multiple Sclerosis, 2019, Engdahl et al

    Open access, https://www.frontiersin.org/articles/10.3389/fimmu.2019.02715/full Press release, https://eurekalert.org/pub_releases/2019-11/ki-mlt112519.php
  6. Sly Saint

    Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Comprehensive Review Aug 2019 Rivera, Mastronardi, Silva-Aldana,Arcos-Burgos,Lidbury

    Review article MDPI Diagnostics Received: 22 May 2019; Accepted: 15 July 2019; Published: 7 August 2019 full text here https://www.mdpi.com/2075-4418/9/3/91/htm (not familiar with any of the authors)
    • Sly Saint
    • Thread
    • 2019 central nervous system cns lidbury mastronardi me/cfs neuroendocrine paper review rivera
    • Replies: 5
    • Forum: ME/CFS research
  7. Patient4Life

    Spinal Cord Warmth and Shivering

    Lately I sometimes have, upon awakening, a spinal cord I feel a shiver through and it is warm. The shivering lasts a few seconds while the warmth a minute, maybe two. The only time I had this was coming off Cymbalta many years ago. It happened during the day. But, it was hot and caused a lot of...
  8. Webdog

    CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature, 2018, Louveau et al

    Abstract - https://www.nature.com/articles/s41593-018-0227-9 Article: Lymphatic Vessels of Brain Carry Messages That Appear to Promote MS, Study Reports https://multiplesclerosisnewstoday.com/2018/09/20/brains-lymphatic-vessels-carry-messages-that-may-promote-ms-study-reports/
  9. Andy

    Brain inflammatory cascade controlled by gut-derived molecules

    https://www.nature.com/articles/d41586-018-05113-0
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