biomarker

https://www.europeanreview.org/wp/wp-content/uploads/8519-8536.pdf See table 1 for protein vs HCs. Brought up as I read a post by @Andy about a possible study on salivary peptide fatigue testing in me/cfs. Could this be useful to find a biomarker in me/cfs?

https://otd.harvard.edu/news/nanoneedle-technology-licensed-for-early-disease-detection-biomarker-discov/

Abstract Neurological disorders, including neurodegenerative diseases, are collectively a major cause of death and disability worldwide. Whilst the underlying disease mechanisms remain elusive, altered mitochondrial function has been clearly implicated and is a key area of study in these...

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a persistent and unexplained pathological state characterized by exertional and severely debilitating fatigue, with/without infectious or neuropsychiatric symptoms, and with a minimum duration of 6 consecutive months. Its...

Highlights • ME/CFS is characterized by skewed B cell receptor gene usage. • Upregulation of specific IGHV genes correlated to infection-related episodes at onset. • Plasmablasts of ME/CFS patients upregulated interferon response genes. • B cell receptor repertoire analysis can provide a useful...

Prototype. "Monitoring the effects of daily activities on the physiological responses of the body calls for wearable devices that can simultaneously track metabolic and haemodynamic parameters. Here we describe a non-invasive skin-worn device for the simultaneous monitoring of blood pressure...

Recursive ensemble feature selection provides a robust mRNA expression signature for myalgic encephalomyelitis/chronic fatigue syndrome https://www.nature.com/articles/s41598-021-83660-9

https://www.mdpi.com/2218-273X/11/2/185

Open access, https://www.mdpi.com/2077-0383/10/4/623/htm

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-021-02713-9

I have a feeling that OMF might be closing in on a biomarker. But if there is a biomarker and it reflects something downstream, is it possible that the biomarker might not be useful in identifying treatments? Are there examples of other diseases where a biomarker was found, but it was not...

Full title: Are Circulating FGF21 and NT-proBNP promising novel biomarkers in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome? https://www.liebertpub.com/doi/abs/10.1089/ars.2020.8230

https://www.nature.com/articles/s41598-020-77105-y

Google translated: The Canadian Press MONTREAL - A new test developed by Montreal researchers is expected to improve the diagnosis and treatment of patients with myalgic encephalomyelitis (ME), a condition better known as chronic fatigue syndrome. L'EM is currently diagnosed primarily by...

https://www.mdpi.com/journal/biomolecules/special_issues/Biomarkers_in_CFS https://twitter.com/BhupeshPrusty/status/1324791213745184769

Researchers at McMaster and Brock universities in Canada have developed a hand-held device that can provide rapid measurements of cancer biomarkers in blood samples.

https://euraxess.ec.europa.eu/jobs/545894

Paywall, https://content.iospress.com/articles/work/wor203177 Sci hub, https://sci-hub.tw/10.3233/WOR-203177

Free full text: https://bmccardiovascdisord.biomedcentral.com/articles/10.1186/s12872-020-01465-6

To paraphrase, "We've found changes in the brains of people with "FSS", this then proves that "FSS" is valid category! It certainly doesn't mean that there is an actual disease mechanism at work, oh no!" :banghead: Open access...