Mini Review ARTICLE
Marta Lombardi1, Martina Gabrielli1, Elena Adinolfi2 and Claudia Verderio1*
1CNR Institute of Neuroscience, Research Labs–University Milano-Bicocca, Vedano al Lambro, Italy
2Department of Medical Sciences, Section of Experimental Medicine, University of Ferrara, Ferrara...
Summary
Aerobic glycolysis, or preferential fermentation of glucose-derived pyruvate to lactate despite available oxygen, is associated with proliferation across many organisms and conditions. To better understand that association, we examined the metabolic consequence of activating the pyruvate...
https://www.pnas.org/content/early/2020/06/16/2002250117
popular article here https://newsroom.uw.edu/news/study-yields-clues-how-drug-may-boost-aged-mitochondria
Title:Suggested Pathology of Systemic Exertion Intolerance Disease: Impairment ofthe E3 Subunit or Crossover of Swinging Arms of the E2 Subunit of the Pyruvate Dehydrogenase Complex Decreases Regeneration of Cofactor DihydrolipoicAcid of the E2 Subunit
Abtract:Systemic Exertion Intolerance...
As this came up in a different thread, I thought it would be worth creating a separate thread for it.
Open access at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946674/
I think this might be of interest to us but really it's so technical I'm out of my depth.
What caught my attention was recalling that this recent study claimed that itaconate is an anti-inflammatory metabolite (recent forum thread on the study here) and reading the Wikipedia article that...
Cara Tomas, Audrey Brown, Victoria Strassheim, Joanna Elson, Julia Newton, Philip Manning
Plos One 2017 oct
Abstract
Chronic fatigue syndrome (CFS) is a highly debilitating disease of unknown aetiology. Abnormalities in bioenergetic function have been cited as one possible cause for CFS...
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