antibodies

Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating disorder characterized by serious physical and cognitive impairments. Recent research underscores the role of immune dysfunction, including the role of autoantibodies, in ME/CFS pathophysiology. Expanding on...

Circulating miRNAs in the Plasma of Post-COVID-19 Patients with Typical Recovery and Those with Long-COVID Symptoms: Regulation of Immune Response-Associated Pathways Timofeeva, Anna M.; Nikitin, Artem O.; Nevinsky, Georgy A. Following the acute phase of SARS-CoV-2 infection, certain...

Thomas Vogl at the Medical University of Vienna, Austria, together with colleagues at the University Medical Center Groningen, the Netherlands, plan to use their Global Grant for Gut Health to identify potential biomarkers for long COVID by screening for antibodies against hundreds of thousands...

Free: https://journals.lww.com/painrpts/fulltext/2024/08000/antibody_mediated_autoimmunity_in_symptom_based.4.aspx MEETING PROCEEDINGS Antibody-mediated autoimmunity in symptom-based disorders: position statement and proceedings from an international workshop Abstract A 2-day closed workshop...

PASC Post Acute Sequelae of COVID-19 is associated with decreased neutralizing antibody titers in both biological sexes and increased ANG-2 and GM-CSF in females Jansen, Ethan B.; Ostadgavahi, Ali Toloue; Hewins, Benjamin; Buchanan, Rachelle; Thivierge, Brittany M.; Sganzerla Martinez, Gustavo...

ACE-2-like enzymatic activity is associated with immunoglobulin in COVID-19 patients Yufeng Song; Regan Myers; Frances Mehl; Lila Murphy; Bailey Brooks; Jeffrey M. Wilson; Alexandra Kadl; Judith Woodfolk; Steven L. Zeichner Many mechanisms responsible for COVID-19 pathogenesis are...

Here we report preliminary data demonstrating that some patients with myalgic encephalomyelitis/chronic fatiguesyndrome (ME/CFS) may have catalytic autoantibodies that cause the breakdown of myelin basic protein (MBP). We propose that these MBP-degradative antibodies are important to the...

Abstract Among the unknowns in decoding the pathogenesis of SARS-CoV-2 persistent symptoms in Long Covid is whether there is a contributory role of abnormal immunity during acute infection. It has been proposed that Long Covid is a consequence of either an excessive or inadequate initial immune...

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Free-water-corrected diffusion and adrenergic/muscarinic antibodies in myalgic encephalomyelitis/chronic fatigue syndrome Yukio Kimura; Wakiro Sato; Norihide Maikusa; Miho Ota; Yoko Shigemoto; Emiko Chiba; Elly Arizono; Hiroyuki Maki; Isu Shin; Keiko Amano; Hiroshi Matsuda; Takashi Yamamura...

SARS-CoV-2 Spike Protein Binding of Glycated Serum Albumin-Its Potential Role in the Pathogenesis of the COVID-19 Clinical Syndromes and Bias towards Individuals with Pre-Diabetes/Type 2 Diabetes and Metabolic Diseases Iles J, Zmuidinaite R, Sadee C, Gardiner A, Lacey J, Harding S, Ule J...

Class switch towards non-inflammatory, spike-specific IgG4 antibodies after repeated SARS-CoV-2 mRNA vaccination Pascal Irrgang, Juliane Gerling, Katharina Kocher, Dennis Lapuente, Philipp Steininger, Katharina Habenicht, Monika Wytopil, Stephanie Beileke, Simon Schäfer, Jahn Zhong, George...

Biomarkers in the diagnostic algorithm of myalgic encephalomyelitis/chronic fatigue syndrome Gravelsina Sabine, Vilmane Anda, Svirskis Simons, Rasa-Dzelzkaleja Santa, Nora-Krukle Zaiga, Vecvagare Katrine, Krumina Angelika, Leineman Iana, Shoenfeld Yehuda, Murovska Modra Myalgic...

Revisiting IgG antibody reactivity to Epstein-Barr virus in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and its potential application to disease diagnosis Abstract: Infections by the Epstein-Barr virus (EBV) are often at the disease onset of patients suffering from Myalgic...

Abstract Background: Long COVID is a condition characterized by long-term sequelae persisting after the typical convalescence period of COVID-19. Previous reports have suggested the role of an unsatisfactory immune response and impaired viral clearance in the pathogenesis of long COVID...

The US Food and Drug Administration (FDA) has approved efgartigimod (Vyvgart, argenx), a first-in-class, targeted therapy for adults with generalized myasthenia gravis (gMG) who test positive for the antiacetylcholine receptor (AChR) antibody... Full text at...

Full title: Severe Fatigue and Memory Impairment Are Associated with Lower Serum Level of Anti-SARS-CoV-2 Antibodies in Patients with Post-COVID Symptoms Abstract Background: Post-COVID manifestation is defined as persistent symptoms or long-term complications beyond 4 weeks from disease...

Predictors of Nonseroconversion after SARS-CoV-2 Infection https://wwwnc.cdc.gov/eid/article/27/9/21-1042_article ____________________ CDC study finds that 36% of COVID patients never make antibodies This has implications for prevalence studies of long covid that assume a lack of...

Eric Song, Christopher M. Bartley, Ryan D. Chow, Thomas T. Ngo, Ruoyi Jiang, Colin R. Zamecnik, Ravi Dandekar, Rita P. Loudermilk, Yile Dai, Feimei Liu, Sara Sunshine, Jamin Liu, Wesley Wu, Isobel A. Hawes, Bonny D. Alvarenga, Trung Huynh, Lindsay McAlpine, Nur-Taz Rahman, Bertie Geng, Jennifer...

Preprint. " Abstract Finite mixture models have been widely used in antibody (or serological) data analysis in order to help classifying individuals into either antibody-positive or antibody-negative. The most popular models are the so-called Gaussian mixture models which assume a Normal...