Exactly, the ME/CFS enterovirus research pioneered in Britain was not really proven wrong, but simply psychobabbled out of existence. Yes, they ignored the British research in the US. But the reason the significant body of British enterovirus research was discounted over the pond is because US researchers tried to replicate the positive British findings, but got a negative result. But, whereas the British researchers were testing ME/CFS patient muscle tissues and finding chronic enterovirus infections there, the US researchers tested the blood of ME/CFS patients, and did not find the infection. But as Dr John Chia is at pains to point out, in ME/CFS the infections are in the tissues, not the blood. Quite a simple thing to understand really, but you'd be surprised how many ME/CFS researchers don't seem to. Even virus hunter extraordinaire, Prof Lipkin, tested the only blood and CSF, but not the tissues. Which explains why his study could not find enterovirus in ME/CFS patients. He's looking in the wrong place if he wants to find enterovirus. Unless you chop out a bit of the patient's tissues out and check the tissues, it's hard to get direct evidence of enterovirus infection. So until researchers start testing the tissues for infection, we are never going to make much progress in ME/CFS viral research. Yes, my explanation above refers to the unpublished negative (but flawed) study in the US. The study was by one Dr Hardy Robart in Denver, USA. At timecode 6:53 in this video of Dr Chia's enterovirus presentation at the NIH's State of Knowledge Workshop on ME/CFS 2011, he explains the failure of the American researchers to replicate the British studies: So they were unable to find enterovirus in ME/CFS patients in the US because they looked in the wrong place. They looked in the blood rather than the muscles. And thereafter, the British enterovirus research was ignored in the US. Until Dr John Chia came along. That I believe is why in the US, interest switched to researching herpesviruses as the possible cause of ME/CFS. Which I guess is a good thing, because it seems that both enteroviruses and herpesviruses are linked to ME/CFS, and in the UK, the focus was solely on enterovirus; so in that respect it's fortunate that the US went down the herpesvirus route. But I'd like to see the US pick up the pieces of the enterovirus research that got blown out decades ago because of Dr Hardy Robart's negative result in 1996. There have been 8 different studies that found enterovirus infection in the muscles of ME/CFS patients. So these muscle biopsy studies are well replicated. But muscle biopsies are painful and leave a scar, and so are not ideal for routine clinical use. Dr John Chia's great innovation is that he realized that in ME/CFS, enterovirus also infects stomach tissues, and that it is much easier to take a stomach tissue biopsy than a muscle biopsy. So this stomach tissue biopsy is what Dr Chia uses in routine clinical use for enterovirus testing. But nota bene that Dr Chia is not saying that enterovirus infection of the stomach is necessarily the cause of ME/CFS; don't forget that other studies have found chronic enterovirus in the muscles and brain tissues too, so the infection is widespread in the body. Dr Chia just found that the stomach is an accessible tissue, which makes routine biopsies of the stomach for enterovirus testing straightforward. Yes, biopsies on the brain can only really be performed on deceased patients, but 3 different ME/CFS brain autopsy studies all found good evidence of chronic enterovirus infection in the brain, whereas none of the control brains were infected.