The clinical features included blisters/skin peeling, cold hands/feet, dark circles under eyes, discoloured fingers/toes, dermatological symptoms, extreme paleness, hair loss, hyperhidrosis, red/cracked lips, red welts, tingling feeling, twitches, chronic fatigue syndrome, impaired attention, listlessness, muscle weakness, orthostatic intolerance, tiredness/weakness, dizziness when standing, altered taste, anosmia/ageusia or parosmia/eusomia, body weight changes, constipation, problem swallowing, skipping meals, vomiting, depression, memory impairment, psychiatric symptoms, sadness, unexplained irritability, change in menstruation, chills, enlarged lymph nodes, neurological symptoms, problem seeing/blurred vision, problem speaking/communicating, seizures/fits, stiffness, hoarse voice, chest tightness, hearth rhythm disturbances, pulmonary embolism, respiratory symptoms, shortness of breath with activity, tachypnoea, nasal congestion and wheezing.