USA: Mount Sinai PACS clinic and Dr David Putrino

Jonathan Edwards said:
Well if he 'shared early results' it wasn't triple blind, was it?

I can guarantee that a low level magnetic field will have no useful effect on neuroinflammation that isn't there. This is a situation where the mind has to be kept open enough for the brain to fall out.
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I share your skepticism on the therapy but I assume it means they have unblinded and are writing/have written the paper?

Or am I missing something?
 


“Hi! We are slated for first-in-human mitochondrial transplantation this year. AND my announcement about the MMT therapy was 100% home-based. I’m excited to provide all sorts of options to all patients. My role is to build functional, actionable toolkits, not to sell magic bullets”

Putrino doing mitochondrial transplants—he is a man of many skills!

Who is we?
 
Jaybee00 said:


“Hi! We are slated for first-in-human mitochondrial transplantation this year. AND my announcement about the MMT therapy was 100% home-based. I’m excited to provide all sorts of options to all patients. My role is to build functional, actionable toolkits, not to sell magic bullets”

Putrino doing mitochondrial transplants—he is a man of many skills!

Who is we?
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Why is it that people who flog poorly evidenced treatments always go on about there not being magic bullets, like that makes their poorly evidenced treatment more appealing?
 
Felis Catus said:
Treatment studies we've got from Putrino:
- MeoHealth breathing programme
- pacing using Visible
- MMT using a Fareon device for neuroinflammation
- Boluoke lumbrokinase supplement for microclots

I think he's missing acupuncture.
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He was also part of one of the Paxlovid trials with negative results and is running a Rapamycin study in LC and ran a VNS study in Long-Covid (the study completed 2 years ago but I can't find him publishing on it). He's also running a Sana Pain Reliever study in post treatment Lyme disease. Much to the joy of @Jonathan Edwards he recently completed an exercise study in Osteoarthritis with a high risk of bias.
 
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EndME said:
He was also part of one of the Paxlovid trials with negative results and is running a Rapamycin study in LC and ran a VNS study in Long-Covid. He's also running a Sana Pain Reliever study in post treatment Lyme disease. Much to the joy of @Jonathan Edwards he recently completed an exercise study in Osteoarthritis with a high risk of bias.
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Also note that he published an exercise study in Long-Covid of quality much lower than PACE Autonomic conditioning therapy reduces fatigue and improves global impression of change in individuals with post-acute COVID-19 syndrome @dave30th
 
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N_Dina said:


The study “Audio-visual stimulation therapy for chronic neuropathic pain: a sham-controlled randomized clinical trial”.
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This randomized controlled trial explored the efficacy of a wearable Audio-Visual Stimulation neuromodulation device (Sana) as a novel intervention for chronic NP in 75 participants.
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Results​

For the main outcome (Neuropathic Pain Symptom Inventory total), there were statistically significant improvements in the Active arm that were greater than those in the Sham Arm at Week-14 (Mean Difference = 8.75, p = 0.021). Both groups showed significant improvements at the end of the treatment period (Week-10), and the Active arm maintained this improvement after an additional 4 weeks of non-use, while the Sham arm almost returned to baseline (Active Change = 11.7, p < = 0.001 | Sham Change = 3, p = 0.24). Participants in the Active arm had significant decreases in use of anxiolytic, opiate, antidepressant, and anticonvulsant medications compared to the Sham arm.

Conclusions​

The study provides strong evidence supporting the efficacy of a novel AVS Device in generating durable improvements in NP, with superiority over Sham at 14 weeks. The Sana device may also reduce the reliance on pain medications and is a safe and easy to use treatment option for patients
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It's so obvious once you see it, but outside of biomedical research, medicine has almost completely abandoned even the pretense of plausibility. Any dumb thing for any reason in any combination is worth trying, dozens and dozens of identical times, if it's popular enough. And if it's really popular, then it's worth trying indefinitely. Literally.

I have no doubt that if science and technology stopped progressing, if no more answers came out of basic research and biomedical science, fortunately not a credible scenario, then medicine could genuine, seriously reach its millionth trial of CBT for something or another and never find fault with that. I mean that 100% seriously. They can't stop the gravy trolley, it just rolls on its own inertia now, and the heavier it is the more force it has because it's set up to run downhill.

Almost all of evidence-based medicine, and all of biopsychosocial/psychosomatic ideology, is nothing more than a clickfluencer economy. Whatever gets people to applaud like seals, doesn't matter how ridiculous, is what gets all the attention, which then gets more seal-clapping, and so on. All based on culture. This stuff is simply Traditional Western Medicine.

And yet biomedical research is still producing incredible results, so all of this is a choice between something that works incredibly well, and something that has never once worked, and the choice is almost universal that the implausible garbage feels so much better.
 
rvallee said:
It's so obvious once you see it, but outside of biomedical research, medicine has almost completely abandoned even the pretense of plausibility. Any dumb thing for any reason in any combination is worth trying, dozens and dozens of identical times, if it's popular enough. And if it's really popular, then it's worth trying indefinitely. Literally.

I have no doubt that if science and technology stopped progressing, if no more answers came out of basic research and biomedical science, fortunately not a credible scenario, then medicine could genuine, seriously reach its millionth trial of CBT for something or another and never find fault with that. I mean that 100% seriously. They can't stop the gravy trolley, it just rolls on its own inertia now, and the heavier it is the more force it has because it's set up to run downhill.

Almost all of evidence-based medicine, and all of biopsychosocial/psychosomatic ideology, is nothing more than a clickfluencer economy. Whatever gets people to applaud like seals, doesn't matter how ridiculous, is what gets all the attention, which then gets more seal-clapping, and so on. All based on culture. This stuff is simply Traditional Western Medicine.

And yet biomedical research is still producing incredible results, so all of this is a choice between something that works incredibly well, and something that has never once worked, and the choice is almost universal that the implausible garbage feels so much better.
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It seems like you're overindexing on this.

David Putrino has publicly stated that his strategy is to get manufacturers to fund trials privately. The fact that his trials look like this is unsurprising.

Remember, he's just one researcher of many.
 
Liface said:
It seems like you're overindexing on this.

David Putrino has publicly stated that his strategy is to get manufacturers to fund trials privately. The fact that his trials look like this is unsurprising.

Remember, he's just one researcher of many.
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Any word on that viral persistence test you mentioned you were working towards?
 
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