hinterland
Senior Member (Voting Rights)
https://www.theguardian.com/world/2...tenary-first-world-war?CMP=Share_iOSApp_Other
In an era before antibiotics and vaccines, the “Spanish influenza” – so-called because neutral Spain was one of the few countries in 1918 where correspondents were free to report on the outbreak – claimed the lives of nearly 250,000 Britons. Cruelly for a nation that had seen the flower of British male youth mown down by German guns, the majority were adults aged 20 to 40. The mortality was the inverse of most flu seasons, when deaths fall most heavily on the elderly and the under-fives.
But perhaps the biggest unanswered question is why the Spanish flu proved so deadly to young adults. Here, present-day science has hypotheses but no good answers. One suggestion is that the elderly enjoyed greater immunity because, as children, they had been exposed to a pandemic virus with a similar genetic makeup to the H1N1 Spanish flu. Conversely, those aged 28 and over had an immunological blind spot because their first exposure had been to the 1890 “Russian flu”, an H3 virus with a completely different configuration of genes. Or it could be that the unusual mortality pattern seen in 1918 was the result of an as yet unidentified environmental exposure or stressor peculiar to young adults at the time.