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Press Release: France ASFC to clinically evaluate ME/CFS pathogenesis model by Bio-Modeling Systems

Discussion in 'BioMedical ME/CFS Research' started by NelliePledge, Jul 19, 2018.

  1. NelliePledge

    NelliePledge Moderator Staff Member

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    picked this up from facebook post by International Alliance for ME

    http://www.bmsystems.net/download/p...drome-validation-english-CS-ASFC-17072018.pdf

    Paris, France July 17, 2018: The Scientific Committee of the French Chronic Fatigue Syndrome Association (ASFC) has decided to evaluate in clinic the CADI™ (Computer Assisted Deductive Integration) model of CFS pathogenesis mechanisms produced by Bio-Modeling Systems (BMSystems) to bring novel diagnostic and therapeutic strategies faster to patients.

    The two organizations will combine their competencies to improve understanding of the physiopathology and to accelerate treatment discovery for this poorly served, debilitating disorder for which challenges are considerable and therapeutic approaches non-satisfactory. To this end, the partners have launched an innovative research program which combines the scientific and clinical know-how of the Scientific and Medical teams attached to the Association with BMSystems’ heuristic CADI™ Discovery modeling platform and the scientific talents of its team of biologists. More specifically, BMSystems has constructed a CADI™ model that, by integrating immunological dysregulations with their systemic metabolic, physiological and cognitive consequences, describes and explains the causal CFS mechanisms and their modes of clinical progression, leading to the formulation of potential targeted treatments.

    The purpose of this collaboration is to evaluate in the clinic the CADI™ model's predictions and open new avenues that will be decisive for the understanding, the diagnosis and the treatment of the disease. The CADI™ model construction was entirely self-financed by BMSystems, revealing its confidence to jointly identify and characterize mechanisms that will quicker provide specific combined therapies to the patients.

    The scientific program is placed under the shared leadership of Pr. Jean-Dominique de Korwin (Department of Internal Medicine, University Hospital of Nancy, Lorraine University) President of the Scientific Committee of the ASFC, Dr. François Iris, founder & CSO of BMSystems and Dr. Thanos Beopoulos, Integrative Biologist at BMSystems.
     
  2. NelliePledge

    NelliePledge Moderator Staff Member

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  3. Jonathan Edwards

    Jonathan Edwards Senior Member (Voting Rights)

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    That sounds rather like some sort of -babble to me.
     
  4. mariovitali

    mariovitali Senior Member (Voting Rights)

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    @NelliePledge

    They use some techniques (NLP + information Extraction, Network Analysis) that i have been using as well. They also utilise some methods that resemble to what Dr Robert Phair is doing with his Software and the "Metabolic Trap" Hypothesis.

    I am looking forward to what their methods will tell. In the end, it is the result (or lack of) that matters.
     
  5. Alvin

    Alvin Senior Member (Voting Rights)

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    If we can model the unknown then we have achieved a great feat. In fact i think this technology should also be used for greater purposes and will win the inventors fame and fortune.
     
  6. TiredSam

    TiredSam Moderator Staff Member

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    NLP? What does that stand for please?
     
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  7. mariovitali

    mariovitali Senior Member (Voting Rights)

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    Last edited: Jul 21, 2018
  8. Trish

    Trish Moderator Staff Member

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    I'm glad you explained that. The NLP most of us have heard of on this forum is Neuro Linguistic Programming which as far as I understand it is an unproven psychotherapy used by some very dodgy people.
     
  9. NelliePledge

    NelliePledge Moderator Staff Member

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    possibly, I suspect the translation from French hasnt helped with clarity
     
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  10. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    I'm not sure if this is related or not (the article is from before this announcement):
    (not a very good translation)
    "To extend the work of the Americans, and the Pr of Korwin and its scientific council, now have two goals : to better identify the "real" patients, the most severe, and to propose the appropriate treatment.

    Thus, the specialist works a part in the development of a questionnaire which will soon be sent to the 700 French patients of the association and, on the other hand, the development of a framework of support based on therapeutic education, an approach that includes informing the patient to make an expert of his disease and active."

    https://www.sciencesetavenir.fr/san...chronique-maladie-meconnue-des-francais_28621

    @Cheshire
     
  11. Cheshire

    Cheshire Moderator Staff Member

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    Sorry to answer that late (I was wiped out when I saw it and then forgot :bag:)

    I don't know what to think about anything set up by the ASFC. It's always a mix of good and very bad things. I do not expect much...
     
  12. Sly Saint

    Sly Saint Senior Member (Voting Rights)

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    "
    BMSystems’ heuristic CADI™ Discovery model proposes the first treatment for ME/CFS by integrating the pathology's immunological dysregulations with their systemic metabolic, physiological and cognitive consequences. The model developed in close collaboration with the French Chronic Fatigue Syndrome Association provides thorough understanding of the causal ME/CFS mechanisms and their modes of clinical progression. The treatment, already validated by a clinical proof of concept will enter in a phase II clinical trial with our partner."

    https://www.bmsystems.org/me-cfs
     
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