Paroxysmal Kinesigenic Dyskinesia Symptoms Markedly Reduced with Parenteral Vitamins and Minerals: A Case Report, 2019, Bruton & Fuller

[Andy]

ABSTRACT
Introduction: Paroxysmal kinesigenic dyskinesia (PKD) is a rare movement disorder triggered by sudden voluntary movements. The disorder involves attacks of chorea, which resolve within minutes, that may occur frequently throughout the day.

Case Presentation: A 61-year-old woman presented to the clinic with a 13-year history of PKD first diagnosed in 2002. This patient had frequent episodic attacks of PKD, which were so severe she had difficulty with ambulation and other activities of daily living. The case was complicated by an additional diagnosis of chronic fatigue syndrome. She refused antiseizure medication because of concerns about it exacerbating her fatigue. In the office, she was given weekly parenteral doses of vitamins and minerals, which almost completely eliminated her symptoms between treatments and allowed her to return to activities of daily living.

Discussion: Genetic testing, not related to her PKD diagnosis, revealed several mutations that could offer an explanation for the apparent efficacy of parenteral therapy in this patient.

Open access, http://www.thepermanentejournal.org/issues/2019/fall/7263.html

 

[Mithriel]

This intrigues me. I have PKD (as well as PNKD, non kinesgnic) and over the years have come across people with ME who have it as well. I also had a friend with MS who had it who was told that neurological disease can make a mild genetic case apparent.

First of all, how lucky is she that she has not been written off as having FND? Wow! Movement disorders including PKD are the poster child for FND with them claiming over 50% of movement disorders are FND.

Then we must ask whether it is the volume of liquid in the infusions which is causing the improvement because of the great results from Dr Bell in Lyndonville who used saline infusions to increase blood volume. They had to be discontinued because of the problem with collapsing veins and infected stents to the dismay of patients.