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Oxidative stress caused by a dysregulated Wnt/β-catenin signalling pathway... abnormal placenta ... in pregnant mice with CFS, 2020, Zhao et al

Discussion in 'BioMedical ME/CFS Research' started by Dolphin, Oct 19, 2020.

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  1. Dolphin

    Dolphin Senior Member (Voting Rights)

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    https://www.cambridge.org/core/jour...gue-syndrome/732B77AB5F851B50AC2886C97DE5D7F2

    Oxidative stress caused by a dysregulated Wnt/β-catenin signalling pathway is involved in abnormal placenta formation in pregnant mice with chronic fatigue syndrome

     
    Dolphin, Oct 19, 2020
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  2. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Pregnant mice with CFS? How do we know, did we ask the mice? :facepalm:
     
    Snow Leopard, Oct 20, 2020
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  3. Michiel Tack

    Michiel Tack Senior Member (Voting Rights)

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    Why do they have to use the name CFS? Why not simply speak of exhausted mice or something like that?
     
    Michiel Tack, Oct 20, 2020
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  4. chrisb

    chrisb Senior Member (Voting Rights)

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    You should see their answers to the Chalder Fatigue Questionnaire.
     
    chrisb, Oct 20, 2020
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  5. Hutan

    Hutan Moderator Staff Member

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    :rofl:

    Setting aside the fundamental issue of no real animal model of CFS, I'm not sure that even this statement about prevalence of gynaecological issues and sexual dysfunction in CFS is true. The only epidemiological study on this I can recall was very flawed.
     
    Hutan, Oct 20, 2020
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  6. Dolphin

    Dolphin Senior Member (Voting Rights)

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    The CDC studies on this used the so-called empiric criteria which give a prevalence of 2.54%. I would give them the prize as the worst criteria, even worse than the Oxford criteria.
     
    Last edited: Oct 20, 2020
    Dolphin, Oct 20, 2020
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  7. Mithriel

    Mithriel Senior Member (Voting Rights)

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    They never listen to patients so they have probably not noticed that mice can't use language.
     
    Mithriel, Oct 20, 2020
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  8. Mij

    Mij Senior Member (Voting Rights)

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    mice.png
     
    Mij, Oct 20, 2020
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