Cheshire
Senior Member (Voting Rights)
Multidimensional studies
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome at the National Institutes of Health
Lead researcher: Avindra Nath
National Institute of Neurological Disorders and Stroke (NINDS)
Study Start Date: January 21, 2016
Estimated Study Completion Date: September 15, 2020
More information
Dr Avindra Nath presenting the study (video)
ME/CFS Severely ill Big Data Study
Open Medicine Foundation
More information
NIH ME/CFS centers: (S4ME thread)
*Cornell ME/CFS Collaborative Research Center
Lead researcher: Maureen Hanson, Ph.D.
Cornell University, Ithaca, New York
Center registration
More information
Main research projects:
- Brain imaging study, led by Dikoma Shungu (See the neurology studies list below for more information)
- Extracellular vesicles, led by Hanson (See the immunology studies list below for more information)
- RNAs in white blood cells, led by Andrew Grimson (See the genetic studies list below for more information)
* Center for Solutions for ME/CFS
Lead researcher: W. Ian Lipkin, M.D.
Columbia University, New York City
Center registration
More Information
*Topological Mapping of Immune, Metabolomic and Clinical Phenotypes to Reveal ME/CFS Disease Mechanisms
Lead researcher: Derya Unutmaz, M.D.
The Jackson Laboratory, Farmington, Connecticut
Center registration
More Information
*Data Management and Coordinating Center (DMCC) for the ME/CFS Collaborative Research Centers
Lead researcher: Rick L. Williams, Ph.D.
Research Triangle Institute, Research Triangle, North Carolina
Center registration
ME/CFS Collaborative Research Center at Stanford
Lead researcher: Ronald W. Davis
Research projects:
T cells and the molecular immunology of ME/CFS
Extended big data study in families
Developing blood-based diagnostic and drug screening technology
More information
S4ME thread
Immunology
Immune System Dysfunction
Lead researchers: Professor Stephen Todryk and Professor Julia Newton
ME Association Ramsay Research Fund / Action for ME
Start: 2014
More information
Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS) (CycloME) Treatment study
Lead researchers: Mella Olav, Øystein Fluge
Haukeland University Hospital
Start: 2015
Estimated Study Completion Date: January 2017
More information
The role of autoantibodies in ME/CFS
Lead researchers: Dr Madlen Löbel & Prof. Carmen Scheibenbogen
Institute of Medical Immunology, Charité University Medicine Berlin, Berlin, Germany
MERUK
More Information
An immunosignature assay for rituximab therapy?
Lead researcher: Prof. David Patrick
School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, USA
MERUK
More information
Lymphocyte phenotype and cytokine production in ME/CFS patients and patients treated with chemotherapy for breast cancer
Lead researchers: Dr Clive Carter, Dr Philip Wood and colleagues
Leeds NHS Teaching Hospital NHS Trust, St James’s University Hospital, Leeds
MERUK
More information
Ampligen in Chronic Fatigue Syndrome Treatment study
Hemispherx
Study Start Date: March 1997
Estimated Study Completion Date: February 2019
More information
S4ME thread
Extracellular vesicles
Lead researcher: Maureen Hanson
Cornell Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Collaborative Research Center
More Information
Combatting oxidative stress
Lead researchers: Dr Faisel Khan, Prof JD Hayes, Prof J Belch, et al.
Vascular & Inflammatory Diseases Research Unit, Division of Cardiovascular & Diabetes Medicine and Division of Cancer Research, Ninewells Hospital & Medical School, Dundee, UK
MERUK
More information
Immunoadsorption in patients with autoantibodies to ß adrenergic receptors Treatment study
Lead researcher: Carmen Scheibenbogen
Charité, Berlin, Germany
Fresenius Medical Care
More information (German)
HyQvia in patients with immunoglobulin deficiency, frequent infections and CFS Treatment study
Charité, Berlin, Germany
Baxalta
More information (German)
Information on HyQvia
Chronic fatigue syndrome: Leptin, interleukin 6 and clinical symptoms
Lead researcher: Michael Musker
South Australian Health And Medical Research Institute (SAHMRI), Australia
More information
Immuno-senescence and cell-cycle analysis in the pathophysiology of ME/CFS
Lead researchers: Dr. Sheila Stewart, Dr. Masashi Narita
Washington University (USA), Cambridge University (UK)
SMCI
More information
Biomarkers for initiation (infection) and metabolic derangement in ME/CFS
Lead researchers: Drs. Blomberg, Bergquist, Gottfries, and Zachrisson
Gottfries clinic, Mölndal, Uppsala University Hospital (Sweden)
SMCI, Ramsay Award Program (2017)
Start: 2018
More information
Immunometabolism of T cells and monocytes in ME/CFS
Lead researchers: Drs. Carmen Scheibenbogen and Franziska Sotzny
Charité – Universitätsmedizin Berlin (Germany)
SMCI, Ramsay Award Program (2017)
Start: 2018
More information
Metabolic Analysis of B Cell Maturation
Lead researchers: Chris Armstrong, Fane Mensah and Professor Jo Cambridge
Melbourne Bioanalytics (Australia), University College London (UK)
SMCI, Ramsay Award Program (2016)
More information
SMCI presentation
Metabolic Assessment of Natural Killer Cells
Lead researchers: Drs. Isabel Barao-Silvestre, Ruben Dagda, and Victor Darley-Usmar
University of Nevada Reno, University of Alabama, Birmingham (USA)
SMCI, Ramsay Award Program (2016)
More information
Identifying Autoimmune signatures in ME/CFS
Lead researchers: Dr. Carmen Scheibenbogen and Madlen Lobel
Charité University Medicine Berlin, Charité Universitatsmedizin Berlin (Germany)
SMCI, Ramsay Award Program (2016)
More information
The potential role of HHV-6 in ME/CFS
Lead researcher: Bhupesh Prusty
Julius Maximilian University of Wurzburg (Germany)
SMCI, Ramsay Award Program (2016)
More information
Investigation of human endogenous retrovirus expression in individuals with myalgic encephalomyelitis
Lead researcher: Dr Camila Malto Romano
USP - Universidade de São Paulo (Brazil)
Using UK ME CFS Biobank
More information
Droplet digital PCR for evaluation of associations between human Herpes virus infection and Myalgic encephalomyelitis/chronic fatigue syndrome(ME/CFS)
Lead researchers: Eleanor Riley, Jackie Cliff
London Sch/Hygiene & Tropical Medicine
More information
A longitudinal immunological and virological study for ME CFS biomarker discovery
Lead researcher: Luis Nacul
London Sch/Hygiene & Tropical Medicine
More information
Defining autoimmune aspects of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
PhD research: Katharine Seton
Invest in ME
More information
Energy metabolism
Examining Mitochondria in ME/CFS
Lead researcher: Dr Karl Morten
ME Association Ramsay Research Fund
Using UK Biobank samples
Start: 2017
More information
S4ME thread
Comparison of results from a commercial and NHS blood test to assess mitochondrial function
Lead researcher: Dr Sarah Jayne Boulton
ME Association Ramsay Research Fund
More information
Abnormalities in Mitochondrial Function in Skeletal Muscle
Lead researcher: Professor Anne McArdle
ME Association Ramsay Research Fund/Medical Research Council
Preliminary results (2015)
More information
Bioenergetics capacity, ATP production and potential drug targets using advanced technologies
Lead researcher: Dr. Ralph Garippa
Memorial Sloan Kettering Cancer Center (MSKCC), New York City (USA)
SMCI
More information
Projects
Longitudinal metabolic and genomic study
Lead researcher: Chris Armstrong
Melbourne Bioanalytics, Australia
More information
Mitochondrial Respiratory Function and Cellular Metabolism in Lymphoblasts
Lead researcher: Chris Armstrong, Daniel Missailidis and Paul Fisher
Melbourne Bioanalytics, LaTrobe University, Australia
More information
Muscles studies
Investigating abnormalities in AMPK activation
Lead researcher: Dr Audrey Brown
Institute of Cellular Medicine, Newcastle University, Newcastle, UK
MERUK
More information
Muscle metabolites in patients before and after exercise
Lead researchers: Pr. Kevin Conley, Pr. David Maughan
University of Washington
SMCI, Cathleen J. Gleeson PhD Fund
More information
Neurology studies
Neurological biomarkers in paediatric ME/CFS
Lead researcher: Dr Sarah Knight and colleagues
Murdoch Children’s Research Institute, The Royal Children’s Hospital, University of Melbourne, Melbourne, Australia
MERUK
More information
Markers of neuroinflammation and oxidative stress
Lead researcher: Dikoma Shungu
Cornell Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Collaborative Research Center
More information
Interrogating the brain: experiments with laser-evoked potentials and cerebral blood flow
Lead researchers: Prof. J. Nijs, Prof P. Cras, Prof F. visser, M. de Kooning and colleagues
Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
MERUK
More information
Development of surrogate end-point biomarkers for chronic fatigue and myalgic encephalmyelitis/chronic fatigue syndrome (ME/CFS)
Lead researcher: Watanabe
Pet Scan study
Japan
More Information
S4ME thread
Exploring Brain Inflammation
Lead researcher: Dr. Jarred Younger
University of Alabama, Birmingham (USA)
SMCI, Ramsay Award Program (2016)
More information
Projects
Glial activation in brainstem
Dr. Michael VanElzakker
Massachusetts General Hospital
More information
S4ME thread
Autonomic system
ME/CFS: Activity Patterns and Autonomic Dysfunction
Lead researcher: Fred Friedberg
Stony Brook University New York, United States
NIH funds
Study Start Date: June 2016
Estimated Study Completion Date: May 2020
More information
S4ME Thread
If you have questions or want to make a suggestion, please go to the Librairy Discussions thread.
Myalgic Encephalomyelitis/Chronic Fatigue Syndrome at the National Institutes of Health
Lead researcher: Avindra Nath
National Institute of Neurological Disorders and Stroke (NINDS)
Study Start Date: January 21, 2016
Estimated Study Completion Date: September 15, 2020
More information
Dr Avindra Nath presenting the study (video)
ME/CFS Severely ill Big Data Study
Open Medicine Foundation
More information
NIH ME/CFS centers: (S4ME thread)
*Cornell ME/CFS Collaborative Research Center
Lead researcher: Maureen Hanson, Ph.D.
Cornell University, Ithaca, New York
Center registration
More information
Main research projects:
- Brain imaging study, led by Dikoma Shungu (See the neurology studies list below for more information)
- Extracellular vesicles, led by Hanson (See the immunology studies list below for more information)
- RNAs in white blood cells, led by Andrew Grimson (See the genetic studies list below for more information)
* Center for Solutions for ME/CFS
Lead researcher: W. Ian Lipkin, M.D.
Columbia University, New York City
Center registration
More Information
*Topological Mapping of Immune, Metabolomic and Clinical Phenotypes to Reveal ME/CFS Disease Mechanisms
Lead researcher: Derya Unutmaz, M.D.
The Jackson Laboratory, Farmington, Connecticut
Center registration
More Information
*Data Management and Coordinating Center (DMCC) for the ME/CFS Collaborative Research Centers
Lead researcher: Rick L. Williams, Ph.D.
Research Triangle Institute, Research Triangle, North Carolina
Center registration
ME/CFS Collaborative Research Center at Stanford
Lead researcher: Ronald W. Davis
Research projects:
T cells and the molecular immunology of ME/CFS
Extended big data study in families
Developing blood-based diagnostic and drug screening technology
More information
S4ME thread
Immunology
Immune System Dysfunction
Lead researchers: Professor Stephen Todryk and Professor Julia Newton
ME Association Ramsay Research Fund / Action for ME
Start: 2014
More information
Cyclophosphamide in Myalgic Encephalopathy/ Chronic Fatigue Syndrome (ME/CFS) (CycloME) Treatment study
Lead researchers: Mella Olav, Øystein Fluge
Haukeland University Hospital
Start: 2015
Estimated Study Completion Date: January 2017
More information
The role of autoantibodies in ME/CFS
Lead researchers: Dr Madlen Löbel & Prof. Carmen Scheibenbogen
Institute of Medical Immunology, Charité University Medicine Berlin, Berlin, Germany
MERUK
More Information
An immunosignature assay for rituximab therapy?
Lead researcher: Prof. David Patrick
School of Population and Public Health, University of British Columbia, Vancouver, British Columbia, USA
MERUK
More information
Lymphocyte phenotype and cytokine production in ME/CFS patients and patients treated with chemotherapy for breast cancer
Lead researchers: Dr Clive Carter, Dr Philip Wood and colleagues
Leeds NHS Teaching Hospital NHS Trust, St James’s University Hospital, Leeds
MERUK
More information
Ampligen in Chronic Fatigue Syndrome Treatment study
Hemispherx
Study Start Date: March 1997
Estimated Study Completion Date: February 2019
More information
S4ME thread
Extracellular vesicles
Lead researcher: Maureen Hanson
Cornell Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Collaborative Research Center
More Information
Combatting oxidative stress
Lead researchers: Dr Faisel Khan, Prof JD Hayes, Prof J Belch, et al.
Vascular & Inflammatory Diseases Research Unit, Division of Cardiovascular & Diabetes Medicine and Division of Cancer Research, Ninewells Hospital & Medical School, Dundee, UK
MERUK
More information
Immunoadsorption in patients with autoantibodies to ß adrenergic receptors Treatment study
Lead researcher: Carmen Scheibenbogen
Charité, Berlin, Germany
Fresenius Medical Care
More information (German)
HyQvia in patients with immunoglobulin deficiency, frequent infections and CFS Treatment study
Charité, Berlin, Germany
Baxalta
More information (German)
Information on HyQvia
Chronic fatigue syndrome: Leptin, interleukin 6 and clinical symptoms
Lead researcher: Michael Musker
South Australian Health And Medical Research Institute (SAHMRI), Australia
More information
Immuno-senescence and cell-cycle analysis in the pathophysiology of ME/CFS
Lead researchers: Dr. Sheila Stewart, Dr. Masashi Narita
Washington University (USA), Cambridge University (UK)
SMCI
More information
Biomarkers for initiation (infection) and metabolic derangement in ME/CFS
Lead researchers: Drs. Blomberg, Bergquist, Gottfries, and Zachrisson
Gottfries clinic, Mölndal, Uppsala University Hospital (Sweden)
SMCI, Ramsay Award Program (2017)
Start: 2018
More information
Immunometabolism of T cells and monocytes in ME/CFS
Lead researchers: Drs. Carmen Scheibenbogen and Franziska Sotzny
Charité – Universitätsmedizin Berlin (Germany)
SMCI, Ramsay Award Program (2017)
Start: 2018
More information
Metabolic Analysis of B Cell Maturation
Lead researchers: Chris Armstrong, Fane Mensah and Professor Jo Cambridge
Melbourne Bioanalytics (Australia), University College London (UK)
SMCI, Ramsay Award Program (2016)
More information
SMCI presentation
Metabolic Assessment of Natural Killer Cells
Lead researchers: Drs. Isabel Barao-Silvestre, Ruben Dagda, and Victor Darley-Usmar
University of Nevada Reno, University of Alabama, Birmingham (USA)
SMCI, Ramsay Award Program (2016)
More information
Identifying Autoimmune signatures in ME/CFS
Lead researchers: Dr. Carmen Scheibenbogen and Madlen Lobel
Charité University Medicine Berlin, Charité Universitatsmedizin Berlin (Germany)
SMCI, Ramsay Award Program (2016)
More information
The potential role of HHV-6 in ME/CFS
Lead researcher: Bhupesh Prusty
Julius Maximilian University of Wurzburg (Germany)
SMCI, Ramsay Award Program (2016)
More information
Investigation of human endogenous retrovirus expression in individuals with myalgic encephalomyelitis
Lead researcher: Dr Camila Malto Romano
USP - Universidade de São Paulo (Brazil)
Using UK ME CFS Biobank
More information
Droplet digital PCR for evaluation of associations between human Herpes virus infection and Myalgic encephalomyelitis/chronic fatigue syndrome(ME/CFS)
Lead researchers: Eleanor Riley, Jackie Cliff
London Sch/Hygiene & Tropical Medicine
More information
A longitudinal immunological and virological study for ME CFS biomarker discovery
Lead researcher: Luis Nacul
London Sch/Hygiene & Tropical Medicine
More information
Defining autoimmune aspects of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)
PhD research: Katharine Seton
Invest in ME
More information
Energy metabolism
Examining Mitochondria in ME/CFS
Lead researcher: Dr Karl Morten
ME Association Ramsay Research Fund
Using UK Biobank samples
Start: 2017
More information
S4ME thread
Comparison of results from a commercial and NHS blood test to assess mitochondrial function
Lead researcher: Dr Sarah Jayne Boulton
ME Association Ramsay Research Fund
More information
Abnormalities in Mitochondrial Function in Skeletal Muscle
Lead researcher: Professor Anne McArdle
ME Association Ramsay Research Fund/Medical Research Council
Preliminary results (2015)
More information
Bioenergetics capacity, ATP production and potential drug targets using advanced technologies
Lead researcher: Dr. Ralph Garippa
Memorial Sloan Kettering Cancer Center (MSKCC), New York City (USA)
SMCI
More information
Projects
Longitudinal metabolic and genomic study
Lead researcher: Chris Armstrong
Melbourne Bioanalytics, Australia
More information
Mitochondrial Respiratory Function and Cellular Metabolism in Lymphoblasts
Lead researcher: Chris Armstrong, Daniel Missailidis and Paul Fisher
Melbourne Bioanalytics, LaTrobe University, Australia
More information
Muscles studies
Investigating abnormalities in AMPK activation
Lead researcher: Dr Audrey Brown
Institute of Cellular Medicine, Newcastle University, Newcastle, UK
MERUK
More information
Muscle metabolites in patients before and after exercise
Lead researchers: Pr. Kevin Conley, Pr. David Maughan
University of Washington
SMCI, Cathleen J. Gleeson PhD Fund
More information
Neurology studies
Neurological biomarkers in paediatric ME/CFS
Lead researcher: Dr Sarah Knight and colleagues
Murdoch Children’s Research Institute, The Royal Children’s Hospital, University of Melbourne, Melbourne, Australia
MERUK
More information
Markers of neuroinflammation and oxidative stress
Lead researcher: Dikoma Shungu
Cornell Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Collaborative Research Center
More information
Interrogating the brain: experiments with laser-evoked potentials and cerebral blood flow
Lead researchers: Prof. J. Nijs, Prof P. Cras, Prof F. visser, M. de Kooning and colleagues
Faculty of Physical Education and Physiotherapy, Vrije Universiteit Brussel, Brussels, Belgium
MERUK
More information
Development of surrogate end-point biomarkers for chronic fatigue and myalgic encephalmyelitis/chronic fatigue syndrome (ME/CFS)
Lead researcher: Watanabe
Pet Scan study
Japan
More Information
S4ME thread
Exploring Brain Inflammation
Lead researcher: Dr. Jarred Younger
University of Alabama, Birmingham (USA)
SMCI, Ramsay Award Program (2016)
More information
Projects
Glial activation in brainstem
Dr. Michael VanElzakker
Massachusetts General Hospital
More information
S4ME thread
Autonomic system
ME/CFS: Activity Patterns and Autonomic Dysfunction
Lead researcher: Fred Friedberg
Stony Brook University New York, United States
NIH funds
Study Start Date: June 2016
Estimated Study Completion Date: May 2020
More information
S4ME Thread
If you have questions or want to make a suggestion, please go to the Librairy Discussions thread.
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