Obscure late 70s' yacht rock band. Peaked at 172 on the Saskatchewan charts.generic fluff
Obscure late 70s' yacht rock band. Peaked at 172 on the Saskatchewan charts.generic fluff
Obscure late 70s' yacht rock band. Peaked at 172 on the Saskatchewan charts.
Yes, yes, yes.Naturopathic doctors aren't the solution to primary care: doctors, health experts
Amid a family doctor shortage in Canada, many naturopathic doctors position themselves as a solution, arguing that they have the training to be a patient’s primary care provider.
That’s raising alarm among medical doctors and health experts who say they are not equipped to be a patient’s principal source of medical care.
“Naturopaths presenting themselves as a solution to our current crisis is at the very least misleading. And from the perspective of a family physician, it’s quite horrifying,” said Dr. Sarah Bates, acting president of the Alberta Medical Association’s family medicine section.
https://ottawa.citynews.ca/2024/03/...o-primary-care-crisis-doctors-health-experts/
Summary
Background
Postpartum blues (PPB) is a frequent syndrome of sad mood, crying spells, anxiety, restlessness, reduced appetite, and irritability, typically peaking day 5 postpartum. When severe, it greatly increases risk for later postpartum depression. This trial compared a dietary supplement to placebo on PPB severity. The supplement was designed to counter downstream effects of elevated monoamine oxidase A level, implicated in causing PPB.
Methods
Participants recruited by advertisement from the Toronto region completed procedures at CAMH, Canada and/or participants’ homes. Oral supplement or identical appearing relatively inert placebo were administered in randomised, double-blind fashion. Supplement was blueberry juice and extract given four times between nighttime day 3 and morning day 5 postpartum; tryptophan 2 g nighttime day 4 postpartum, and tyrosine 10 g morning day 5 postpartum. On day 5, depressed mood induction procedure (MIP) and postpartum blues were assessed. All data is presented (NCT03296956 closed, clinicaltrials.gov).
Findings
Between January 2019 and December 2022, participants took supplement (n = 51) or placebo (n = 52). There was no significant effect on primary outcome MIP on visual analogue scale for depressed mood (mean difference = −0.39 mm, 95% CI: −6.42 to 5.65 mm). Stein Maternity Blues scores, exploratory PPB measure, was lower in the active group (effect size 0.62; median, interquartile range (IQR): active 2.00 (IQR 1, 4); placebo 4.00 (IQR 1.5, 6); regression with general linear model, supplement effect, β coefficient = −1.50 (95%: CI −2.60, −0.40), p = 0.008; effect of CES-D crying category before supplement, p = 0.03–0.00000023). Twenty-six and 40 different adverse events occurred within 25% and 42% of supplement and placebo cases respectively (Chi-Square, p = 0.06).
Interpretation
The primary outcome was negative for effect on depressed mood induction, however the supplement moderately reduced PPB.
Evidence before this study
To identify studies using dietary supplements to prevent or reduce symptoms of postpartum blues or postpartum depression, Pubmed, Psychinfo and Cochrane databases were searched for any relevant articles from 1995 to March 2020 using key words including postpartum blues, postpartum depression, postnatal depression and prevention. The search was done prior to the start of the study and repeated March 23, 2020; and published as part of a review. There was one negative trial of docosahexaenoic acid with or without arachidonic acid versus placebo on postpartum blues. One trial was positive for lower risk scores for postpartum depression within 8 weeks of giving birth after oral selenium supplementation in a region with frequent selenium deficiency.
Added value of this study
The supplement reduced postpartum blues with an effect size of 0.62 but did not have effect on depressed mood induction.
No, no social, no bio, only psycho. That's the biopsychosocial way, most letters are actually silent, need to be spoken with a dog whistle.Or we could, as a society, make sure that women who have recently given birth or have very young children have adequate post-natal social and economic support.
Now that is something the psychosocial crowd should be sinking their teeth into.