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Neuropsychological and neurophysiological correlates of fatigue in post-acute pts with neurological manifestations of COVID-19 (2021) Ortelli et al

Discussion in 'Epidemics (including Covid-19)' started by strategist, Jan 25, 2021.

  1. strategist

    strategist Senior Member (Voting Rights)

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    • Neuropsychological and neurophysiological features of fatigue were studied in post-COVID-19 patients.

    • Apathy, deficits in executive functions and reduction in global cognition were found.

    • Abnormal shortening of cortical silent period and lack of MEP depression were demonstrated after a fatiguing task.

    • Disruption of post-exhaustion corticomotor inhibition suggests GABA-ergic dysfunction.

    • GABA-ergic impairment might subtend fatigue and executive deficits in COVID-19.

    https://www.sciencedirect.com/science/article/abs/pii/S0022510X20306079
     
  2. Joan Crawford

    Joan Crawford Senior Member (Voting Rights)

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    Thanks for posting this. right up my alley :) I'll look at the paper to see what cognitive tests they used. Some are a lot better than others at highlighting the cognitive difficulties patients with ME can face and I suspect log Covid patients perhaps too. Like PASAT and so forth.
     

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