Multi-omics identifies lipid accumulation in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome cell lines: a case-control study, 2026, Missailidis et

Thanks @chillier and @DMissa, very helpful.

The paper reported a lot of good detail about the machines and the techniques in Methods. I think it would also be good to report when analyses are subcontracted out, giving the name of the lab that did the work. For the reasons we have discussed, it does matter who does the work, probably at least as much as which machine was used.

Readers would see the name of the lab and some would immediately have a good idea of the protocols likely to have been applied and the quality of the work.
 
Hutan said:
I think it would also be good to report when analyses are subcontracted out, giving the name of the lab that did the work. For the reasons we have discussed, it does matter who does the work, probably at least as much as which machine was used.
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They are co-authors with their contributions and affiliations listed in the paper:


Daniel Missailidis 1,2,✉, Christopher W Armstrong 3, Dovile Anderson 4, Claire Y Allan 1,2, Oana Sanislav 1,2, Paige K Smith 5, Tammy Esmaili 6, Darren J Creek 4, Sarah J Annesley 1,2,7,#, Paul R Fisher 1,#
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1Department of Microbiology, Anatomy, Physiology and Pharmacology, La Trobe University, Bundoora, VIC Australia
2La Trobe Institute for Molecular Science, La Trobe University, Bundoora, VIC Australia
3Department of Biochemistry and Pharmacology, The University of Melbourne, Melbourne, VIC Australia
4Monash Proteomics and Metabolomics Platform, Drug Delivery Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC Australia
5Monash Health, Melbourne, VIC Australia
6Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, VIC Australia
7La Trobe Institute for Sustainable Agriculture and Food, La Trobe University, Bundoora, VIC Australia


D.M and C.W.A wrote the original draft. D.M, C.W.A and D.A analysed the data. D.M, C.Y.A and O.S cultured and harvested the cell samples. D.A prepared the samples for MS and ran the MS in the laboratory of D.C. P.K.S, T.E, D.M and S.A undertook home visits to collect samples from people with ME/CFS. S.A and P.R.F acquired the funding, conceived the study, advised experimental design and analysis and supervised junior researchers. All authors read and approved the final manuscript.
 
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