Medscape: Do Fatigue and Exercise Intolerance Post-COVID-19 Indicate a Chronic Disease? (CME & Education)

[ahimsa]

[note: I just got this via a Medscape alert, I have not read it yet, just grabbed a few sections for the quote below]

Do Fatigue and Exercise Intolerance Post-COVID-19 Indicate a Chronic Disease?
Authors: News Author: Miriam E. Tucker; CME Author: Charles P. Vega, MDFaculty and Disclosures
CME / ABIM MOC / CE

Released: 11/4/2022
Valid for credit through: 11/4/2023

https://www.medscape.org/viewarticle/983265

Long COVID can affect up to half of patients with COVID-19, but has the relatively less severe symptomatology associated with the Omicron variant resulted in lower rates of long COVID? A small, single-center study performed in Japan by Morioka and colleagues sought to answer this question, and the results of their research were published in the August 11, 2022, issue of the Journal of Infection and Chemotherapy.
...

From its first description, long COVID has been compared with myalgic encephalitis/chronic fatigue syndrome (ME/CFS). The current study assesses how many patients with long COVID meet criteria for ME/CFS.
...

A new study provides yet more evidence that a significant subset of people who experience persistent fatigue and exercise intolerance after COVID-19 will meet diagnostic criteria for ME/CFS.

Data from the prospective observational study of 42 patients with "post-COVID-19 syndrome (PCS)," including persistent fatigue and exercise intolerance, suggest that a large proportion will meet strict diagnostic criteria for ME/CFS, including the hallmark postexertional malaise (PEM). Still others may experience similar disability but lack duration and/or severity requirements for the diagnosis.

Moreover, disease severity and symptom burden were found to be similar in those with ME/CFS after COVID-19 and in a group of 19 age- and sex-matched individuals with ME/CFS that was not associated with COVID-19.

 

[Denise]

I wonder why it refers to ME/cfs as myalgic encephalitis/.... I hope that gets corrected....

 

[Sly Saint]

not able to access the full article.

"A new study provides yet more evidence that a significant subset of people who experience persistent fatigue and exercise intolerance after COVID-19 will meet diagnostic criteria for ME/CFS."

does it say what this study is called/ provide a link?

 

[ahimsa]

not able to access the full article.

"A new study provides yet more evidence that a significant subset of people who experience persistent fatigue and exercise intolerance after COVID-19 will meet diagnostic criteria for ME/CFS."

does it say what this study is called/ provide a link?

I think that particular statement is about this study:

https://www.nature.com/articles/s41467-022-32507-6

But here's a copy of the References, just in case I cut/pasted the wrong link:

1. Morioka S, et al. Post COVID-19 condition of the Omicron variant of SARS-CoV-2. J Infect Chemother. 2022;28(11):1546-1551. https://www.jiac-j.com/article/S1341-321X(22)00233-1/fulltext. Accessed September 9, 2022.

2. Kedor C, et al. A prospective observational study of post-COVID-19 chronic fatigue syndrome following the first pandemic wave in Germany and biomarkers associated with symptom severity. Nat Commun. 2022;13(1):5104. https://www.nature.com/articles/s41467-022-32507-6. Accessed September 9, 2022.

3. Carruthers BM, et al. Myalgic encephalomyelitis/chronic fatigue syndrome. J Chronic Fatigue Synd. 2003;11(1):7-115. https://www.tandfonline.com/doi/abs/10.1300/J092v11n01_02. Accessed September 9, 2022.

4. Cotler J, et al. A Brief questionnaire to assess post-exertional malaise. Diagnostics (Basel). 2018;8(3):66. https://www.mdpi.com/2075-4418/8/3/66. Accessed September 9, 2022.

5. Tucker ME. IOM Gives Chronic Fatigue Syndrome a New Name and Definition. February 10, 2015. https://www.medscape.com/viewarticle/839532. Accessed September 9, 2022.

6. Cabral-Marques O, et al. Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severity. Nat Commun. 2022;13(1):1220. https://www.nature.com/articles/s41467-022-28905-5. Accessed September 9, 2022.

7. Flaskamp L, et al. Serum of post-COVID-19 syndrome patients with or without ME/CFS differentially affects endothelial cell function in vitro. Cells. 2022;11(15):2376. https://www.mdpi.com/2073-4409/11/15/2376. Accessed September 9, 2022.

8. Bach K. New data shows long Covid is keeping as many as 4 million people out of work. August 24, 2022. https://www.brookings.edu/research/...ping-as-many-as-4-million-people-out-of-work/. Accessed September 9, 2022.

PS. Medscape requires you to register to see a lot of their content, but they only require an email address and a password. There's no fee.

For privacy reasons I registered with the name "ahimsa ahimsa" and used a nearby zip code (they only asked for country and zip code, not an address). And of course I did not connect any of the accounts they list (google, apple, facebook).

Just putting that out there for folks who want to read Medscape content.