ME researcher Jonas Bergquist - interviews, talks

"Utnyttja kompetensen vi byggt upp på humansidan"
https://www.slu.se/fakulteter/vh/forskning/gastprofessorer/jonas-bergquist/

Google Translate, English ("Utilise the skills we have built up on the human side")

Lovely interview

 

Jonas Bergquist was mentioned in a news article today:

Läkaren Artur Fedorowski användes i Amelieklinikens forskning – utan hans vetskap
https://www.svt.se/nyheter/inrikes/...klinikens-forskning-utan-hans-vetskap--zfr3kn

Also posted in the News from Scandinavia thread here:
https://www.s4me.info/threads/news-from-scandinavia.647/page-92#post-506633

 

Analysis of tryptophan metabolites and related compounds in human and murine tissue: development and validation of a quantitative and semi-quantitative method using high resolution mass spectrometry
https://pubs.rsc.org/en/content/articlelanding/2024/ay/d3ay01959d

 

Anyone interested in this analysis might find this wikipedia diagram of some help in understanding it :

https://upload.wikimedia.org/wikipedia/commons/2/24/Tryptophan_metabolism.svg

 

From OMF email newsletter:

Research Summary: From the Desk of Dr. Jonas Bergquist:

“Our recent study, published in the Analytical Methods Journal, aimed to investigate the levels of tryptophan metabolites in human plasma using an advanced technique called high-resolution mass spectrometry. Tryptophan is an essential amino acid that plays a crucial role in various metabolic processes. Disruptions in its pathway have been implicated in several diseases.

Our goal is to incorporate this methodology in our upcoming study to analyze plasma samples from people diagnosed with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) and comparing them to samples from healthy individuals, to uncover potential mechanisms involved in the development of this debilitating disease. This study supports the Kynurenine trap model for ME/CFS, shedding light on the pathogenesis of the condition. We hope that our findings will contribute to a deeper understanding of ME/CFS.”

 

Video interview, 5 minutes long, in Swedish. Published by RME.

He talks a bit about the LIFT study (a combination of LDN and mestinon), and the so called "home visit study" (the the data collection and analysis is done, they are working on the statistics part now. They have found that mitochondrial markers such as lactate, and some cell metabolism markers, are significantly altered.)

https://www.youtube.com/watch?v=jB7KSdaPh2w