ME/CFS Research at the Quadram Institute, Norwich, UK

Not new News, but as we didn't have a dedicated thread for this topic I thought I'd create one.

https://quadram.ac.uk/targets/me-cfs/

Profile for research leader, Prof Simon Carding

https://quadram.ac.uk/simon-carding/

And his personal Quadram Institute profile, https://quadram.ac.uk/people/simon-carding/

Recent papers that he was a named author on that are, or may be, of interest. (Not intended to be an exhaustive list).
Review article: Does the microbiome and virome contribute to myalgic encephalomyelitis/chronic fatigue syndrome?
https://www.s4me.info/threads/revie...ic-fatigue-syndrome-2018-newberry-et-al.2871/

Review article: Fantastic voyage: the journey of intestinal microbiota-derived microvesicles through the body
https://www.s4me.info/threads/fanta...les-through-the-body-2019-carding-et-al.9834/

 

It would be very fortunate if it helped explain, at least in part, the mechanism of IBS, as there seems to be many similarities. IBS a clear target for the MUS cult, because not a single lesson was learned from the peptic ulcers / H. pylori debacle, and things will only get worse if they are allowed to get a grip on it.

 

http://www.investinme.org/IIMER-Newslet-190603CentreNews.shtml

and my recent Q&A with Prof Carding that includes discussion of those things, https://www.s4me.info/threads/video...on-carding-quadram-institute-june-2019.10186/

 

https://quadram.ac.uk/gp-fellowship-me-cfs/

ETA:
https://twitter.com/user/status/1156541990080827392

 

https://twitter.com/user/status/1156930928452800512

 

MA Photography student's work on display at ME conference

https://flexible.falmouth.ac.uk/abo...ents-work-on-display-at-me-conference_270.htm

The Royal Photographic Society’s 2019 Science Photographer Of The Year Shortlist

https://designyoutrust.com/2019/08/...9-science-photographer-of-the-year-shortlist/

(note: also featured in the Guardian)

 

https://twitter.com/user/status/1177972504914284550


https://www.uea.ac.uk/study/postgraduate/research-degrees/phds-and-studentships/uea-phds

 

Prof Carding’s boots are made for walking

https://quadram.ac.uk/blogs/prof-cardings-boots-are-made-for-walking/

 

Dr Katharine Seton

https://quadram.ac.uk/people/katherine-seton/

 

Dr Katharine Seton receives funding to expand ME research

"Katharine Seton from the Quadram Institute has been awarded a Solve M.E. Ramsay Research Grant to better understand premature ageing of the immune system in people with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS).

The grant will build on current studies linking the immune response to gut microbes. It’s hoped that this will lead to therapies that target the gut microbiome to alleviate ME/CFS symptoms and improve the lives of people with ME/CFS."

https://quadram.ac.uk/katharine-seton-receives-funding-to-expand-me-research/

 

Merged thread

Prescriber article

Realising the potential of faecal microbiota transplant


Angela Dowden

First published: 22 February 2023

Free full text:
https://wchh.onlinelibrary.wiley.com/doi/full/10.1002/psb.2043

Extract:
At the Quadram Institute in Norwich, ethical applications and MHRA trial licence applications are being prepared in anticipation of a clinical trial, beginning mid-2023, that will evaluate the use of FMT in people with myalgic encephalomyelitis (ME) and chronic fatigue syndrome (CFS).

Professor Simon Carding, who will lead the study, supported by the UK Invest in ME Research Charity, explains: “Considering that a significant proportion of ME/CFS patients date the onset of their symptoms to a GI illness, with abdominal pain, diarrhoea and sometimes vomiting, FMT may be helpful in these patients.

“Recent studies identifying changes in the bacteria and viral component of the faecal microbiome in ME/CFS patients have led to the suggestion that intestinal microbial dysbiosis contributes to GI symptoms such as irritable bowel syndrome (IBS) seen in more than 90% of ME/CFS patients.

“A study undertaken in a single centre in Australia has already reported significant clinical improvement in 70% of ME/CFS patients administered an FMT.”

 

https://twitter.com/user/status/1640702708460953601

 

I am glad they made them a colour that no other capsule comes in.

 

indeed.

This image is particularly gross as the capsule & the gloved thumb holding it look filthy.

ugh

 

https://twitter.com/user/status/1662018235577819136

 

Recording of a recent talk of his

 

A recording of the talk is also available on YouTube:

https://www.youtube.com/watch?v=JwoZHHXDWOs