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[ME/CFS]: From Pathophysiological Insights to Novel Therapeutic Opportunities, 2019, Berk et al

Discussion in 'BioMedical ME/CFS Research' started by Andy, Sep 12, 2019.

  1. Andy

    Andy Committee Member & Outreach

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    Paywall, https://www.sciencedirect.com/science/article/abs/pii/S1043661819308011
    Not currently available on Sci hub.
     
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  2. mariovitali

    mariovitali Senior Member (Voting Rights)

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    Regarding NAC (N-AcetylCysteine) : I did try it and within one hour i felt as i couldn't breathe easily. Upon trying to walk on stairs i got very fatigued and my pulse rate went quite up.

    Perhaps one of the best things i heard on the latest symposium was about personalised interventions that address each patient individually.
     
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  3. Trish

    Trish Moderator Staff Member

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    It's available on Sci-hub now as a Journal Pre-proof.
    https://sci-hub.se/https://doi.org/10.1016/j.phrs.2019.104450

    I've only had a quick glance through and this is my impression:

    It's about 38 pages plus a very long list of references.

    It that looks at various kinds of evidence for biological abnormalities in ME first.

    Most of the focus is on various nutriceutical treatments they think might be worth testing. They look at their biological effects using evidence of their effects on animals, and on people with other conditions.

    Then it ends with a section on CBT and GET, concluding they only have slight short term effects and GET can be harmful.

    I imagine the purpose is to try to get funding for some nutriceutical trials.
     
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