ME/CFS Bioinformatics Repository

[tralfamadorian97]

Since the DecodeME preprint was released, I have been teaching myself bioinformatics by analyzing the summary statistics from DecodeME and other GWAS. I’ve been publishing my code on GitHub here, and documenting my results here.

While I don’t have dramatic headline results, I still thought that this work would be of interest to Science4ME forum members, because there are a few analyses that supplement recent forum discussions. For example, I ran gene-level H-MAGMA on the DecodeME summary statistics.

If anyone wants to contribute, I will happily accept fixes or additions to the documentation or codebase. For minor changes, you can just create a GitHub pull request. For major additions, it is probably better to first create a GitHub issue with a brief proposal, which we can discuss.
@forestglip already found the repo and has made some very helpful contributions

 

[forestglip]

It's been incredible watching this project being developed. I stumbled across it a few months ago, and it was immediately obvious tralfamadorian97 is remarkably motivated, organized, and intelligent.

There are a whole lot of different results and even lessons about bioinformatics tools in the documentation which I found very interesting to explore.

 

[hotblack]

Very impressive! Looks like a great resource, thanks for all your work @tralfamadorian97 and for sharing it.