Ivabradine for the Treatment of Postural Orthostatic Tachycardia Syndrome: A Systematic Review, 2018, Gee et al

Discussion in 'Orthostatic intolerance treatments' started by Andy, Feb 3, 2018.

  1. Andy

    Andy Committee Member

    Hampshire, UK
    Paywalled at https://link.springer.com/article/10.1007/s40256-017-0252-1
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  2. MerryB

    MerryB Senior Member (Voting Rights)

    Ivabradine helps me very noticeably - it restores much of my cognitive function. I think it helps to get the blood circulating to my brain better. I take 5mg in the morning and 5mg at night.

    It's the one thingt has made the most difference in my 10 years of living with ME.
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  3. I've been taking a small dose of ivabradine (2.5 mg bid) for the last couple of years for postural tachycardia. I found it to be better for that purpose than even the B[1]-selective beta-blockers, which of course dropped my BP along with my HR, worsening overall orthostatic intolerance; as an I[f] channel blocker, ivabradine's much more of a `pure' heart-rate lowering agent.

    Other than helping to control the postural tachycardia, though, it has absolutely no effect on any of my core ME symptoms.
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