Ivabradine for the Treatment of Postural Orthostatic Tachycardia Syndrome: A Systematic Review, 2018, Gee et al

Paywalled at https://link.springer.com/article/10.1007/s40256-017-0252-1

 

Ivabradine helps me very noticeably - it restores much of my cognitive function. I think it helps to get the blood circulating to my brain better. I take 5mg in the morning and 5mg at night.

It's the one thingt has made the most difference in my 10 years of living with ME.

 

I've been taking a small dose of ivabradine (2.5 mg bid) for the last couple of years for postural tachycardia. I found it to be better for that purpose than even the B[1]-selective beta-blockers, which of course dropped my BP along with my HR, worsening overall orthostatic intolerance; as an I[f] channel blocker, ivabradine's much more of a `pure' heart-rate lowering agent.

Other than helping to control the postural tachycardia, though, it has absolutely no effect on any of my core ME symptoms.