1. Guest, click here to read the 'News in Brief' post for w/c 8th Dec.
    Dismiss Notice
  2. Welcome! To read the Core Purpose and Values of our forum, click here.
    Dismiss Notice

FOX0 pathway

Discussion in 'Health News and Research unrelated to ME/CFS' started by wastwater, Apr 4, 2019.

  1. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
    andypants likes this.
  2. Trish

    Trish Moderator Staff Member

    Messages:
    18,688
    Likes Received:
    96,527
    Location:
    UK
    Hi @wastwater. I admit I am bemused.

    I looked at the diagram you link. It seems to be a complicated network diagram linking lots of biochemical pathways, one of which is labelled FOXO signalling pathway, drawn in the context of a lot of other pathways in a diagram labelled 'cell growth and death and cancer related signal transduction'.

    The paper it is from is
    ''Analyzing the disease module associated with osteosarcoma via a network‑ and pathway‑based approach''

    So it doesn't seem to be showing what the FOXO pathway is, but showing it's connection to other pathways in a particular cancer related context.

    Did you have a particular reason why this is of interest?

     
  3. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
    Hi,I’m thinking I may have reduced FOX01 expression following my rare genetic conditions pathways

    I was surprised to find FOX01 effects the thyroid as I hadn’t seen it before and wondered if this is the reason for my hypothyroidism

    I only wanted to post the links diagram as the rest is a rare condition and probably confuses things

    Then I saw Foxo mentioned in rheumatology and many other conditions
     
    MEMarge and Trish like this.
  4. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
    MEMarge and obeat like this.
  5. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
    obeat likes this.
  6. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
  7. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
  8. wastwater

    wastwater Senior Member (Voting Rights)

    Messages:
    166
    Likes Received:
    436
    Which part of the FOXO pathway is the important bit,is it the effect on T cells,B cells or glucose,all of it on none of it,I wonder.
     
    obeat likes this.

Share This Page