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Evaluation of four clinical laboratory parameters for the diagnosis of myalgic encephalomyelitis (2018) De Meirleir et al

Discussion in 'BioMedical ME/CFS Research' started by hixxy, Nov 23, 2018.

  1. hixxy

    hixxy Senior Member (Voting Rights)

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    https://www.ncbi.nlm.nih.gov/pubmed/30463572
    https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-018-1696-z
     
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  2. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

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    Anybody had time to look at this yet?
     
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  3. unicorn7

    unicorn7 Senior Member (Voting Rights)

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    I hope they will test more people and people with other diseases. I think a biomarker eventually will be different tests taken together to form a diagnosis, so this seems like a good start. We will just have to see if these parameters are really specific for ME.

    I had all these levels tested and in my case it's correct.
     
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  4. Helen

    Helen Senior Member (Voting Rights)

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    My test results (sCD14, PGE and Interleukin 8) were abnormal too.
     
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  5. alex3619

    alex3619 Senior Member (Voting Rights)

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    I have been expecting a finding of elevated PGE2 for two and a half decades. Why does it take so long? (rhetorical question)

    It seemed to me, based on early work by Dr Andriya Martinovic, plus work by Martin L Pall and others, that this was a fully expected consequence. I was trying various treatments based on this idea through most of the 90s.

    By itself PGE2 shows potential pathophysiology, its not diagnostic. I don't want to say anything about the other three substances yet. We will have to see how further research progresses before we know if this is diagnostically useful.
     
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