Moderator note: There is a thread on the symposium here https://www.s4me.info/threads/me-cfs-international-research-symposium-march-2019-australia.6914/ Dr. Ron Davis of Stanford Presents an ME/CFS Research Update. 25/04/2019 Drug Screening Using NanoNeedle Technology Source: Here ========================================================== Summary Two drugs have shown to be effective at reducing the stress response in CFS/ME cells when measured with Nanoneedle biosensors. Copaxone. Used in treating MS relapses. SS31. New unapproved drug which target mitochondria. Detail Dr Ron Davis of Standford University and his team have developed a NanoNeedle technology with the intentions of using it as a diagnostic tool for ME/CFS. The idea is that the patients' cells are unable to cope with stress. So a sample of the patient's blood is dropped onto the NanoNeedle sensor and mixed with sodium chloride (salt), triggering a stress response. 20 severe patients have been tested against controls and show a clear difference in behavior. (see below). The result is repeatable. The team are also using this for drug screening and both Copaxone and SS31 (when added to the blood sample) both normalize the signal. Dr Ron Davis stated that he does not understand why. This could be optimistic data and a early sign of potential treatments. A more conservative idea would be that the drugs are interfering/blocking the signal. I found this finding particularly interesting and I look forward to hearing more from the researchers.