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Did the David Nutt SAFFE Xyrem drug sleep study ever publish?

Discussion in 'BioMedical ME/CFS Research' started by Cinders66, May 2, 2018.

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  1. Cinders66

    Cinders66 Senior Member (Voting Rights)

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    Esther12 likes this.
  2. Adrian

    Adrian Administrator Staff Member

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    I don't remember it being published anywhere and I've wondered about that a few times.
     
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  3. perchance dreamer

    perchance dreamer Senior Member (Voting Rights)

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    The study I heard about was for fibro patients. I don't know what happened to it, but I think it showed very good results. My sleep doctor had been very hopeful the FDA would approve the use of Xyrem for fibro after the favorable study, but they declined, infuriating my doctor.

    I used to have narcolepsy, but recovered from it. I took Xyrem for a number of years and thankfully insurance did pay for it. My copay was usually $40 a month. The out-of-pocket costs would have been astronomical, in the thousands a month. A greed-head company has the patent until 2020, I believe. Talk about the ugly side of American capitalism.
     
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  4. perchance dreamer

    perchance dreamer Senior Member (Voting Rights)

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    Sorry, I just realized you were talking about a UK study. My mind just went to the American study.
     
  5. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

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    Xyrem is GHB, right? That stuff sends me to sleep alright! Now only if they'd licence it for us...
     
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  6. Manganus

    Manganus Established Member (Voting Rights)

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    What about doses and prices?
     
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  7. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

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    I think it's relatively hard to get hold of. I've not tried purchasing it myself.
     
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  8. alktipping

    alktipping Senior Member (Voting Rights)

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    if I remember correctly that was a drug of choice for many gay people in the 80,s and more mainstream recreational drug in the 90.s .from my limited knowledge it cause significant cognitive difficulties severe memory loss .can also lead to psychotic episodes. I would not risk all that for an occasional good nights sleep.
     
  9. adambeyoncelowe

    adambeyoncelowe Senior Member (Voting Rights)

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    It still is. I think the negative side-effects are rather overstated, however. Such is the case with most recreational drugs--and such responses are more politically and socially driven than scientific.

    It's also likely street GHB is mixed with other things or replaced with other substances entirely, so we shouldn't base our assumptions purely on anecdotes of street use.

    Given that ketamine and MDMA are showing promise, and the former always struck me as far more psychoactive than GHB, I suspect it may have uses that should be explored further--if only we could get past our attitudes to recreational drugs in the first place.
     
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  10. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    I don't remember seeing such a study published.
     

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