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Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity, 2018, Bjorkstrom et al

Discussion in 'Other health news and research' started by Andy, Jun 11, 2018.

  1. Andy

    Andy Committee Member

    Hampshire, UK
    Open access at https://www.nature.com/articles/s41467-018-04685-9

    Article about the study
  2. Mij

    Mij Senior Member (Voting Rights)

    The Canadian Association for the Study of the Liver, a national group of health-care providers and researchers, published its guidelines on testing and treating hepatitis C. It was in the news recently and it's recommended that testing should be for Canadians in a certain age bracket (born between 1945 and 1975).

    I was tested many years ago to rule that out.
  3. mariovitali

    mariovitali Senior Member (Voting Rights)


    Thank you for posting this paper.

    cc : @JaimeS @Hip

    In the link @Andy provided we read that Chronic Hepatitis C Infection impacts NK Cell diversity. Moreover in another paper we read that ME/CFS patients were found having low NK Cell Activity.

    I found an interesting paper that connects TYRO3 (A Vitamin K-related Gene) with NK cell functions :

    Link can be found here

    TYRO3 potential relevance has been found by Machine Learning Methods, here is a post from May 2017 :


    Professor @Jonathan Edwards Do you believe this may be relevant?
    Last edited: Sep 1, 2018
    Amw66 and adambeyoncelowe like this.
  4. Amw66

    Amw66 Senior Member (Voting Rights)

    Interestingly my aunt had really bad Hep C in her youth....really bad ME now...
  5. Milo

    Milo Senior Member (Voting Rights)

    It is because Canadian blood banks (also affecting blood products) did not test for Hep C during that time range and people may have been exposed to Hep C may it be from birth, or other mean of getting it (blood transfusion, blood-blood exposure such as sharing needles).
    andypants, Mij and adambeyoncelowe like this.

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