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Chronic hepatitis C virus infection irreversibly impacts human natural killer cell repertoire diversity, 2018, Bjorkstrom et al

Discussion in 'Health News and Research unrelated to ME/CFS' started by Andy, Jun 11, 2018.

  1. Andy

    Andy Committee Member & Outreach

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    Open access at https://www.nature.com/articles/s41467-018-04685-9

    Article about the study
    https://ki.se/en/news/immune-system-does-not-recover-despite-cured-hepatitis-c-infection
     
  2. Mij

    Mij Senior Member (Voting Rights)

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    The Canadian Association for the Study of the Liver, a national group of health-care providers and researchers, published its guidelines on testing and treating hepatitis C. It was in the news recently and it's recommended that testing should be for Canadians in a certain age bracket (born between 1945 and 1975).

    I was tested many years ago to rule that out.
     
  3. mariovitali

    mariovitali Senior Member (Voting Rights)

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    @Andy

    Thank you for posting this paper.

    cc : @JaimeS @Hip

    In the link @Andy provided we read that Chronic Hepatitis C Infection impacts NK Cell diversity. Moreover in another paper we read that ME/CFS patients were found having low NK Cell Activity.

    I found an interesting paper that connects TYRO3 (A Vitamin K-related Gene) with NK cell functions :

    Link can be found here

    TYRO3 potential relevance has been found by Machine Learning Methods, here is a post from May 2017 :

    http://algogenomics.blogspot.com/20...al&utm_source=twitter.com&utm_campaign=buffer

    Professor @Jonathan Edwards Do you believe this may be relevant?
     
    Last edited: Sep 1, 2018
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  4. Amw66

    Amw66 Senior Member (Voting Rights)

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    Interestingly my aunt had really bad Hep C in her youth....really bad ME now...
     
  5. Milo

    Milo Senior Member (Voting Rights)

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    It is because Canadian blood banks (also affecting blood products) did not test for Hep C during that time range and people may have been exposed to Hep C may it be from birth, or other mean of getting it (blood transfusion, blood-blood exposure such as sharing needles).
     
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