In my view, looking for a biomarker and pathology of the disease should supersede research on what’s up with Vitamin D and whether supplement x-y and z is helpful for ME. These studies take time and resources that are limited and take away from the major research questions that need to be answered in order to understand this disease and its subgroups. So much work needs to be done. So little researchers, and so little money.Yes he indicated, it was worth looking at Vitamin D, and environment, and toxicity, and supplements, and all these were potential projects