Can fatigue after aneurism be treated?

[Kalliope]

Oslo University Hospital has an ongoing study about treatment of fatigue after aneurysm. It sounded a bit interesting. Any thoughts?

OUS: Kan nytt medikament hjelpe mot utmattelse etter aneurismeblødning?
google translation: Can new medication help against fatigue after aneurysm bleeding?

Fatigue also occurs in conjunction with other diseases, such as ME, rheumatism and cancer, but we know little about what actually causes it. In investigations, it has not been possible to find a clear physical cause.

Three doctors and two neuropsychologists at Oslo University Hospital are now working on a study to investigate whether the OSU6162 drug can treat fatigue. This drug does not change the level of neurotransmitters in the brain but makes it easier for the substances in the brain to flow as they should.
In order for the medication to function in this way, there must first be an abnormal activity level in the brain, either too high or low. In other words, it is not a performance-enhancing drug.

If the study is successful, it will open opportunities for other chronic disorders to be treated more effectively than today.

 

[Wonko]

Is this actually a good idea tho?

Presumably the fatigue, the sensation and the mechanism by which it is implemented, exists for a reason. Mechanisms probably don't evolve and survive unless they serve a useful purpose, and given how debilitating fatigue can be it must have a pretty useful biological purpose to explain why it has survived as a thing.

So, deliberately defeating it when it's reason isn't understood, and thus not dealt with, possibly not the wisest thing IMO.

 

[Kalliope]

I have no idea.. But according to the article, none of the patients have yet redrawn from the trial and some are reporting of improvement. But it is placebo-controlled, so it remains to see which group they are in.