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Blood flow in sepsis and ME/CFS

Discussion in 'Cardiovascular and exercise physiology (CPET)' started by Hoopoe, Feb 10, 2019.

  1. Hoopoe

    Hoopoe Senior Member (Voting Rights)

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  2. Yvonne

    Yvonne Senior Member (Voting Rights)

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    This is interesting, thanks for posting. I have long thought that impaired blood flow can explain almost all our symptoms.
     
  3. JemPD

    JemPD Senior Member (Voting Rights)

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  4. Ravn

    Ravn Senior Member (Voting Rights)

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    This blog called "Syndrome A" currently has 4 posts. https://www.syndromea.org/
    1. On Autism & Chronic Fatigue Syndrome
    2. Why Does ME/CFS Look Like Sepsis?
    3. Blood Flow in Sepsis and ME/CFS
    4. ME/CFS, Sepsis & Glycocalyx
    Posts 1 and 3 are discussed separately in the following threads, in different sub-forums ("Methylation; B12; Glutathione; GcMAF" and "Cardiovascular and Respiratory"):
    https://www.s4me.info/threads/syndrome-a-on-autism-chronic-fatigue-syndrome.6480/#post-117926
    https://www.s4me.info/threads/blood-flow-in-sepsis-and-me-cfs.8103/

    I feel the blog deserves a more general discussion. It is essentially about an overarching hypothesis centered on blood vessels. Post 2 gives an overview (long read).

    First impressions (I haven't been able to do a focussed read yet, just a quick skim):

    The author has read a lot of research.
    The author has done a lot of thinking.
    The author is asking a lot of good questions.

    Here is an interesting excerpt from post 4.
    Could this glycocalyx damage explain PEM?

    Could these DAMPS molecules be the mystery factor in the blood that makes healthy cells behave like ME cells when placed into ME plasma?
     
  5. Hutan

    Hutan Moderator Staff Member

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    26,534
    Location:
    Aotearoa New Zealand
    It is interesting.

    It seems that it is quite easy to get a look at this glycocalyx in the blood vessels in a non-invasive way.

    https://www.youtube.com/watch?v=kkZzgwQYdGw




    The video is a full-on advert, but it looks as if a video microscope under the tongue can show what condition the glycocalyx is in. The Glycocheck process is presumably a patented algorithm for assessing various factors and coming up with a number - I'm not endorsing the company or their test.
     
  6. Ravn

    Ravn Senior Member (Voting Rights)

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    Location:
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    "Full-on advert" is an understatement! But it did teach me how to pronounce 'glycocalyx'.

    Interesting to know that there is a technology widely used in research, at least according to the ad, to look at blood flow in the microvascular system. Would it be suitable to look at blood flow issues in ME, too?
     
    ScottTriGuy, Hutan and Andy like this.
  7. Hutan

    Hutan Moderator Staff Member

    Messages:
    26,534
    Location:
    Aotearoa New Zealand
    :D
    I'm not sure I'd take pronunciation advice from that advert. There was something weird going on with the "capil- larries".
     

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