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Autonomic Nervous System Functioning Related to Nocturnal Sleep in Patients With CFS Compared to Tired Controls., 2017, Orjatsalo et al

Discussion in 'BioMedical ME/CFS News' started by Andy, Dec 19, 2017.

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  1. Andy

    Andy Senior Member (Voting Rights)

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    https://www.ncbi.nlm.nih.gov/pubmed/29246267
     
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  2. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    This is interesting, but I wonder if it is just an artefact of being a pilot study with recruitment biases, or whether it is a non-specific marker of fatigue.
     
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  3. arewenearlythereyet

    arewenearlythereyet Senior Member (Voting Rights)

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    I think it is interesting, although I belive that there are many things that go on while we are asleep in addition to cardiology and brain waves etc (endocrine system for one). Hopefully they can do a deeper dive on a much larger study. Can't really tell very much from such a small study (8 people).

    One thing I've noticed on a much smaller study of my own is that the impact of sleep varies quite considerably depending upon how much deep sleep stage I get. There appears to be a correlation between how wired I feel before falling asleep and quality. The wired feeling varies a lot for me and this appears to relate back to when I exceed my exertion limits.

    It would be good to measure sleep quality over a long period of time (8-12 weeks) to see how this varies rather than assume this is a constant and look at symptom intensity alongside in any future study. This may lead to understanding why so many of us have good days and bad days.
     
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  4. lansbergen

    lansbergen Senior Member (Voting Rights)

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    I noticed that too
     
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  5. Joel

    Joel Senior Member (Voting Rights)

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    Interesting area to look at, I'd like to see more research but it needs to be much larger, deeper. It'll be expensive.
     
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  6. Snow Leopard

    Snow Leopard Senior Member (Voting Rights)

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    Yes, the question is whether it predicts or lags. I think this sleep finding may be associated with the 'wired' feeling you mention though.
     

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