Dear All, I wanted to inform you about my application to SolveCFS for a RAMSAY award funding and the final decision. The title of the application was : "The use of artificial intelligence and network analysis methods to identify mechanism(s) responsible for Myalgic Encephalomyelitis/Chronic Fatigue Syndrome" I present the introductory text : The application was scored by two reviewers for Significance, Innovation, Approach and Overall Impact. I believe that it is not right to share the comments of the two reviewers. They were invaluable in making me understand the pros and cons of the solution that was built over the past 6 years and the difficulties i had in communicating the capabilities of this framework. Waiting for the "verdict" was a painstaking process (the application was submitted in July). After all, i waited for this moment since 2013. I was informed yesterday that the application was not successful. I do not -by any means- wish to criticise this decision. I did not have the opportunity to "defend" my application with the reviewers but i do understand that this process may not be applicable. The news took a toll on me. I was prepared for a negative outcome but i also had positive thoughts. Creating such framework was not easy. I had to work very hard and this effort had several negative repercussions on my personal life and also financially-wise as i had to work for many - many hours. I thought that the right thing to do is to finally give up and move on with my life. I then reminded myself that i am symptom-free because i didn't give up and instead persisted in finding a solution for me. As i mentioned in older posts, the great thing about forums is that they leave a written record of whatever is being said. Here are my takeaways : - I would like to particularly Thank @ScottTriGuy for his help and tremendous effort to make this work heard. Also Jane, @wigglethemouse and @Ben H . -I stand strong in believing that AI will be a game-changer for putting the pieces of the puzzle together -I will do anything possible to have results of this work being used by other researchers helping them to better understand the bigger picture. I have ready specific blood tests, compounds and also identified potential sub-problems (e.g Cysteine catabolism, Glutamate metabolism) that may be responsible for the perfect storm we are seeing. Unfortunately under these circumstances this task will not be easy. I will never quit. Ever. Until we find a solution. Stay strong, "Mario"