A Novel Nutriceutical Treatment of Myalgic Encephalitis/Chronic Fatigue Syndrome (ME/CFS): “What it is and what it is not” Frank Comhaire* Emeritus Professor at Department of Endocrinology and Metabolic Diseases, Ghent University Hospital, Belgium Published date: September 30, 2017 Internal Medicine. Research Article Abstract Ten patients suffering from pathology considered to be refractory ME/CFS have been prospectively offered treatment with a novel nutriceutical that increases the activity of pyruvate dehydrogenase and enhances mitochondrial energy production by the aerobic metabolism of the Kreb’s cycle. Whereas half of the patients presented highly significant improvement of their health and condition, the other half did not experience any benefit. The latter patients were found to suffer from different pathology that should be classified as “ME/CFS-nondisease”. http://www.openaccessjournals.com/s...-is-and-what-it-is-not-2165-8048-10002452.pdf ..................................................... Fascinating article. Small study. 5 patients showed significant benefit. The 5 who did not were given thorough medical testing and other causes found and treated. This really impressed me - both as a warning that many of us may have some other condition, and the fact that they showed real care for the patients who were not helped. Edit to add: I'm also very impressed that they published the raw data as part of the article!