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tryptophan

  1. alex3619
    Thread

    Thoughts on IDO2 and ME

    There are some issues and concerns around the IDO2 tryptophan trap hypothesis about ME. These are my current thought directions, and should not be...
    Thread by: alex3619, Jun 14, 2021, 8 replies, in forum: BioMedical ME/CFS News
  2. Jaybee00
    Thread

    MEAction 2021 MECFS researchers video with R Davis,Prusty

    [MEDIA]
    Thread by: Jaybee00, May 12, 2021, 60 replies, in forum: BioMedical ME/CFS News
  3. Andy
    Thread

    Inflammation control & improvement of cognitive function in COVID-19: is there a role for kynurenine 3-monooxygenase inhibition?, Collier et al, 2021

    Full title: Inflammation control and improvement of cognitive function in COVID-19 infections: is there a role for kynurenine 3-monooxygenase...
    Thread by: Andy, Feb 21, 2021, 0 replies, in forum: Epidemics (including Covid-19)
  4. leokitten
    Thread

    The NAD+ Long COVID Theory

    The Team of Doctors and Biohackers Who Seem to Be Successfully Treating “Long Covid” [ATTACH] There’s actually quite a number of research...
    Thread by: leokitten, Feb 8, 2021, 12 replies, in forum: Epidemics (including Covid-19)
  5. Andy
    Thread

    Searching for Peripheral Biomarkers in Neurodegenerative Diseases: The Tryptophan-Kynurenine Metabolic Pathway, 2020, Torok et al

    Neurodegenerative diseases are multifactorial, initiated by a series of the causative complex which develops into a certain clinical picture. The...
    Thread by: Andy, Dec 12, 2020, 1 replies, in forum: Health News and Research unrelated to ME/CFS
  6. Andy
    Thread

    Liquid chromatography-mass spectrometry .. reveals increased levels of tryptophan indole metabolites in .. metabolic syndrome, 2020, Wrobel et al

    Full title: Liquid chromatography-mass spectrometry untargeted metabolomics reveals increased levels of tryptophan indole metabolites in urine of...
    Thread by: Andy, Dec 10, 2020, 10 replies, in forum: Health News and Research unrelated to ME/CFS
  7. Andy
    Thread

    An Insight into the Roles of Dietary Tryptophan and its Metabolites in Intestinal Inflammation and Inflammatory Bowel Disease, 2020, Qi et al

    Inflammatory bowel disease (IBD) is complex, chronic, and relapsing gastrointestinal inflammatory disorders, which includes mainly two conditions,...
    Thread by: Andy, Nov 21, 2020, 1 replies, in forum: Health News and Research unrelated to ME/CFS
  8. Jaybee00
    Thread

    Potential Role of Neuroactive Tryptophan Metabolites in Central Fatigue: Establishment of the Fatigue Circuit, 2020, Yamashita

    https://journals.sagepub.com/doi/full/10.1177/1178646920936279 Central fatigue leads to reduced ability to perform mental tasks, disrupted social...
    Thread by: Jaybee00, Oct 16, 2020, 2 replies, in forum: Health News and Research unrelated to ME/CFS
  9. Andy
    Thread

    Hepatocyte-intrinsic type I interferon signaling reprograms metabolism [..] compensatory mechanism of the tryptophan-kynurenine pathway, 2020, Lercher

    Full title: Hepatocyte-intrinsic type I interferon signaling reprograms metabolism and reveals a novel compensatory mechanism of the...
    Thread by: Andy, Oct 14, 2020, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  10. Andy
    Thread

    Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor, 2020, Scott et al

    Inflammatory bowel diseases (IBDs), including Crohn’s disease and ulcerative colitis, are associated with dysbiosis of the gut microbiome....
    Thread by: Andy, Jul 29, 2020, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  11. Andy
    Thread

    Increased Expression of (IDO) in Vogt-Koyanagi-Harada (VKH) Disease May Lead to a Shift of T Cell Responses Toward a Treg Population, 2020,Zhang et al

    Full title: Increased Expression of Indoleamine 2,3-Dioxygenase (IDO) in Vogt-Koyanagi-Harada (VKH) Disease May Lead to a Shift of T Cell...
    Thread by: Andy, May 22, 2020, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  12. Andy
    Thread

    The Kynurenine connection: how exercise shifts muscle tryptophan metabolism & affects energy homeostasis, the immune system & the brain, 2020, Martin

    Tryptophan catabolism through the kynurenine pathway generates a variety of bioactive metabolites. Physical exercise can modulate kynurenine...
    Thread by: Andy, Mar 28, 2020, 0 replies, in forum: Health News and Research unrelated to ME/CFS
  13. Andy
    Thread

    Serum Metabolic Profiles of the Tryptophan-Kynurenine Pathway in the high risk subjects of major depressive disorder, 2020, Sakurai et al

    Previous reports have shown that during chronic inflammation, the tryptophan (TRP)-kynurenine (KYN) pathway plays a pivotal role in the onset of...
    Thread by: Andy, Feb 7, 2020, 1 replies, in forum: Health News and Research unrelated to ME/CFS
  14. John Mac
    Thread

    The IDO Metabolic Trap Hypothesis for the Etiology of ME/CFS 2019 Kashi, Davis, Phair.

    Abstract Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a debilitating noncommunicable disease brandishing an enormous worldwide...
    Thread by: John Mac, Jul 26, 2019, 45 replies, in forum: BioMedical ME/CFS Research
  15. NelliePledge
    Thread

    Stanford Community Symposium 2018: Phair, Metabolic traps, Tryptophan trap

    This thread has been split from the main Stanford Community Symposium 2018 thread. Interesting presentation on metabolic traps focussing on...
    Thread by: NelliePledge, Sep 30, 2018, 306 replies, in forum: BioMedical ME/CFS News
  16. Andy
    Thread

    Fibromyalgia Syndrome: A Case Report on Controlled Remission of Symptoms by a Dietary Strategy, 2018, Lattanzio and Imbesi

    A 34-year-old woman suffered from significant chronic pain, depression, non-restorative sleep, chronic fatigue, severe morning stiffness, leg...
    Thread by: Andy, May 19, 2018, 0 replies, in forum: Fibromyalgia and Connective Tissue Disorders
  17. Andy
    Thread

    Effects of anti-inflammatory drugs on the expression of tryptophan-metabolism genes by human macrophages, 2018, Freeman et al

    Abstract Several lines of evidence link macrophage activation and inflammation with (monoaminergic) nervous systems in the etiology of depression....
    Thread by: Andy, Apr 21, 2018, 2 replies, in forum: Health News and Research unrelated to ME/CFS
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