treatment

  1. Paddler

    A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses, 2021, Lin et al

    2021 paper Abstract A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses Xueqiu Lin 1,6, Yanxia Liu 1,6,7, Augustine Chemparathy 1,2,6, Tara Pande 3, Marie La Russa 1,7, Lei S Qi 1,4,5,7,8,∗ The coronavirus disease 2019 (COVID-19) pandemic caused...
  2. forestglip

    Review Impact of Exercise to Treat Postural Orthostatic Tachycardia Syndrome: A Systematic Review, 2025, Cortez et al

    Impact of Exercise to Treat Postural Orthostatic Tachycardia Syndrome: A Systematic Review Melissa M Cortez, Kayla Aikins, Amy C Arnold, Jeffrey R Boris, Todd E Davenport, Katie Johnson, Hagar S Kattaya, Laurence Kinsella, Mary M McFarland, Ryan Pelo, Clayton D Powers, Kelsi Schiltz, Lauren E...
  3. Mij

    Oral medications for the treatment of POTS; a systematic review of studies before and during the COVID-19 pandemic, 2025, Benjamin C. Pierson et al

    Background: Postural Orthostatic Tachycardia Syndrome (POTS) is a complex form of dysautonomia that presents with abnormal autonomic reflexes upon standing, leading to symptoms such as lightheadedness, tachycardia, fatigue, and cognitive impairment. The COVID-19 pandemic has brought renewed...
  4. forestglip

    Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation, 2023, Salvucci et al

    Antihistamines improve cardiovascular manifestations and other symptoms of long-COVID attributed to mast cell activation Fabrizio Salvucci, Roberto Codella, Adriana Coppola, Irene Zacchei, Gabriella Grassi, Maria Luisa Anti, Nicolita Nitisoara, Livio Luzi, Carmine Gazzaruso Introduction...
  5. Mij

    [Case Report] Treatment of Long Covid with Enoxaparin, 2025, Wright, Kell, Pretorius, Putrino

    Treatment of Long Covid with Enoxaparin, 2025, Wright, Ciara PhD, Kell, Douglas PhD, Pretorius, Resia PhD. Putrino, David PhD Abstract Background and Purpose: Long COVID is a complex multisystemic disease state, which represents a huge economic and health burden worldwide. Hypercoagulation and...
  6. Sly Saint

    Doctors hail first breakthrough in asthma and COPD treatment in 50 years

    Doctors hail first breakthrough in asthma and COPD treatment in 50 years
  7. forestglip

    Oral minocycline therapy as first-line treatment in patients with Myalgic encephalomyelitis and long COVID: A pilot study, 2024, Miwa

    Oral minocycline therapy as first-line treatment in patients with Myalgic encephalomyelitis and long COVID: A pilot study Kunihisa Miwa [In Press, Journal Pre-proof] Background Myalgic encephalomyelitis (ME) is associated with long COVID and also untoward sequelae after anti-coronavirus...
  8. SNT Gatchaman

    Preprint Patient-Reported Treatment Outcomes in ME/CFS and Long COVID, 2024, Eckey, Davis, Xiao+

    Patient-Reported Treatment Outcomes in ME/CFS and Long COVID Martha Eckey; Peng Li; Braxton Morrison; Ronald W Davis; wenzhong xiao Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and Long COVID are persistent multi-system illnesses affecting many patients. With no known effective...
  9. Mij

    A Community-Based Trial of Commercially Available Compression Tights in Patients With POTS, 2024, Kate M. Bourne BSc et al

    Abstract Background Compression garments reduce heart rate and symptoms in patients with postural orthostatic tachycardia syndrome in an acute laboratory setting. Patients taking medications controlling heart rate have less benefit from compression than those not on medications. The...
  10. SNT Gatchaman

    Review Interventions for the management of long covid post-covid condition: living systematic review, 2024, Zeraatkar, Flottorp, Garner, Busse+

    Interventions for the management of long covid post-covid condition: living systematic review Dena Zeraatkar; Michael Ling; Sarah Kirsh; Tanvir Jassal; Mahnoor Shahab; Hamed Movahed; Jhalok Ronjan Talukdar; Alicia Walch; Samantha Chakraborty; Tari Turner; Lyn Turkstra; Roger S McIntyre; Ariel...
  11. forestglip

    Immune stimulation by vaccination e.g. Staphylococcus Toxoid Vaccine, BCG

    Long-Term Treatment with a Staphylococcus Toxoid Vaccine in Patients with Fibromyalgia and Chronic Fatigue Syndrome Carl-Gerhard Gottfries, Ove Häger, Björn Regland, Olof Zachrisson Abstract One hundred and sixty patients with fibromyalgia and chronic fatigue syndrome, who were on a continuous...
  12. Andy

    Pilot study of a parent-based intervention for functional somatic symptoms in children 2024 Etkin et al

    Abstract Objective Functional somatic symptoms are associated with significant distress and impairment for children and their families. Despite the central role that families play in their children’s care, there is little clinical research to guide how parents can support their children with...
  13. SNT Gatchaman

    Trial Report Lithium Aspartate for Long COVID Fatigue and Cognitive Dysfunction: A Randomized Clinical Trial, 2024, Guttuso et al.

    Lithium Aspartate for Long COVID Fatigue and Cognitive Dysfunction: A Randomized Clinical Trial Thomas Guttuso; Jingtao Zhu; Gregory E. Wilding IMPORTANCE Neurologic post–COVID-19 condition (PCC), or long COVID, symptoms of fatigue and cognitive dysfunction continue to affect millions of people...
  14. Sly Saint

    Preventing medication nonadherence: a framework for interventions to support early engagement with treatment 2024 , Chapman, Chalder et al

    ABSTRACT Medication nonadherence is common and results in avoidable morbidity, mortality, and burdens on healthcare systems. This paper proposes a preventative approach to medication nonadherence. We consider existing evidence on the prevalence and determinants of nonadherence early in a...
  15. Yann04

    “Adrenaline Rush” phenomenon— What helps?

    A significant subset (NIH CPET study estimated at 25%) of people with ME experience a phenomenon colloquially described as an “adrenaline rush” during and after overexertion, but before PEM begins. This is characterised by a rush of “fake energy” giving symptoms such as tatycardia, muscle...
  16. Hutan

    Metformin

    Given this recommendation for the use of metformin for people with Post Covid Condition who get a new Covid-19 infection, I thought it was worth having a discussion thread for it in the Treatment section. Relevant research threads can be found by clicking on the metformin tag, top left.
  17. C

    Open UK participants wanted for research on motivations for complementary and alternative treatments in those with chronic illness

    Hello, As part of my psychology Masters at Oxford Brookes University I'm conducting research into the motivations for complementary and alternative medicine use in those with chronic illness. One of the subcategories I'm particularly looking at are those with ME/CFS. If you're a UK resident...
  18. forestglip

    Avoiding crashes as a treatment

    Not sure if there are many other examples, but Ron Davis mentions one potentially successful case (or could be spontaneous remission) of someone recovering after avoiding crashes for a year: "One researcher had ME and she didn't have a crash and after a year she got better."
  19. forestglip

    Evaluating myelophil, a 30% ethanol extract of Astragalus membranaceous and Salvia miltiorrhiza for alleviating fatigue in long COVID 2024 Joung et al

    Evaluating myelophil, a 30% ethanol extract of Astragalus membranaceus and Salvia miltiorrhiza, for alleviating fatigue in long COVID: a real-world observational study 20 June 2024 Jin-Yong Joung, Jin-Seok Lee, Yujin Choi, Yoon Jung Kim, Hyeon-Muk Oh, Hyun-Sik Seo, Chang-Gue Son Background...
  20. E

    Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection, 2024, Geng et al

    Nirmatrelvir-Ritonavir and Symptoms in Adults With Postacute Sequelae of SARS-CoV-2 Infection Key Points Question What is the efficacy of 15 days of nirmatrelvir-ritonavir for improving select symptoms of postacute sequelae of SARS-CoV-2 infection (PASC)? Findings This randomized clinical...
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