t cells

Single-cell RNA-sequencing highlights a curtailed NK cell function in convalescent COVID-19 pregnant women Salker, Madhuri S. ; Abd Aziz, Nor Haslinda ; Prodan, Natalia Carman ; Yang, Zhiqi ; Lankapalli, Aditya Kumar ; Lazar, Katrin ; Shafiee, Mohamad Nasir ; Kocak, Ersoy ; Ganesan, Harivignesh...

In Silico Analysis of Post-COVID-19 Condition PCC Associated SNP rs9367106 Predicts the Molecular Basis of Abnormalities in the Lungs and Brain Functions Maiti, Amit K. Long-or post-COVID-19 syndrome, which is also designated by WHO as Post COVID-19 Condition (PCC), is characterized by the...

Immunological and Clinical Markers of Post-acute Sequelae of COVID-19: Insights from Mild and Severe Cases 6 Months Post-infection William Mouton; Sophia Djebali; Marine Villard; Omran Allatif; Cécile Chauvel; Sarah Benezech; Philippe Vanhems; Jacqueline Marvel; Thierry Walzer; Sophie...

Cytokine profiles associated with persisting symptoms of post-acute sequelae of COVID-19 Ji-Soo Kwon, Euijin Chang, Hyeon Mu Jang, Ji Yeun Kim, Woori Kim, Ju Yeon Son, Junho Cha, Choi Young Jang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim...

Mast cells boost anti-tumor potency of MAIT cells via inflammasome-dependent secretion of IL-18 Fan, Fanfan; Wang, Jun; Liu, Kun; Zhang, Shiyue; Gao, Jian; Li, Xiongfei; Ma, Jiaqiang; Zhao, Yue; Li, Teng; Su, Han; Yang, Xinfeng; Han, Han; Huang, Qingyuan; Zhang, Yiliang; Pan, Yunjian; Ye, Ting...

Wuhan strain of SARS-CoV-2 triggers activation of immune evasion machinery similar to the one operated by cancer cells Abooali, Maryam ; Yasinska, Inna M. ; Thapa, Gauri ; Lei, Xi ; da Costa, Kelly A. S. ; Schlichtner, Stephanie ; Berger, Steffen M. ; Fasler-Kan, Elizaveta ; Temperton, Nigel J...

Gut inflammation promotes microbiota-specific CD4 T cell-mediated neuroinflammation White, Zachary; Cabrera, Ivan; Mei, Linghan; Clevenger, Margarette; Ochoa-Raya, Andrea; Kapustka, Isabel; Dominguez, Joseph R.; Zhou, Jinyan; Koster, Kevin P.; Anwar, Shehata; Wang, Qianxun; Ng, Charles; Sagoshi...

Abstract: Evidence bearing on possible mechanisms for the clinical syndrome of ME/CFS is reviewed. The evidence is used to argue for a hypothesis that centres on a form of persistent, inappropriate, ‘neuroimmune hypervigilance’ mediated primarily by T lymphocyte-macrophage interaction but...

Immune disturbances in individuals with post-COVID syndrome are not characterized by enhanced SARS-CoV-2-specific immunity Ober, Veronica; Völk, Felix; Sbierski-Kind, Julia; Gruener, Eva; Stirner, Renate; Reiling, Gabriele; Feldmann, Svenja; Ibarra, Gerardo; Seybold, Ulrich; Stubbe, Hans...

Hyper-reactivity of CD8+ T cells and high expression of IL-3 correlates with occurrence and severity of Long-COVID Renner; Stauffenberg; Paulus; Neumayer; Winter-Köhler; Buchtler; Schmalenberger; Blaas; Mohr; Pfeifer; Malfertheiner; Loew; Sester; Bals; Peterhoff; Schmidt; Mack Following...

Persistent immune dysregulation and metabolic alterations following SARS-CoV-2 infection Silvia Lucena Lage; Katherine Bricker-Holt; Joseph M. Rocco; Adam Rupert; Frank X. Donovan; Yevgeniya A. Abramzon; Settara C. Chandrasekharappa; Colton McNinch; Logan Cook; Eduardo Pinheiro Amaral; Gabriel...

Dissecting the genetic complexity of myalgic encephalomyelitis/chronic fatigue syndrome via deep learning-powered genome analysis Sai Zhang; Fereshteh Jahanbani; Varuna Chander; Martin Kjellberg; Menghui Liu; Katherine Glass; David Iu; Faraz Ahmed; Han Li; Rajan Douglas Maynard; Tristan Chou...

Characteristic immune cell interactions in livers of children with acute hepatitis revealed by spatial single-cell analysis identify a possible postacute sequel of COVID-19 Felix Röttele; Andreas Zollner; Carolin Mogler; Muhammed Yuksel; Cigdem Arikan; Vivien Karl; Judith Helene Aberle; Stephan...

Abstract: T cells have emerged as orchestrators of pain amplification, but the mechanism by which T cells control pain processing is unresolved. We found that regulatory T cells (Treg cells) could inhibit nociception through a mechanism that was not dependent on their ability to regulate immune...

I’ve been reading/listening to lots about the immune system, particularly B and T cells. And thought it may be worth sharing some links to info I’ve found useful. If others have useful resources please chip in! There’s a lot of sources here and duplication, I found reading/listening to...

Unveiling the Immune Landscape of COVID-19 and prolonged Long-COVID through Single-Cell RNA Sequencing Marta Līva Spriņģe; Kristīne Vaivode; Rihards Saksis; Nineļa Miriama Vainšeļbauma; Laura Ansone; Monta Brīvība; Helvijs Niedra; Vita Rovite Long-COVID affects at least 10% of COVID-19...

929 – Age-Dichotomous Associations of Long COVID With Frequency of Public SARS-CoV-2 Memory TCRs Selin Akbas, Shuai Li, Hao Zhang, Tamilore Adeagbo, Ni Zhao, Alan Landay, Michael Peluso, Elizabeth Thompson, Andrea Cox, Yukari Manabe, Hongkai Ji, Annukka Antar [Line breaks added] Background...

Clinical, histopathological, and radiological characterization of post-acute sequelae of COVID-19 Anna Czech Abstract Numerous patients exhibit enduring symptoms following a Coronavirus Disease 2019 (COVID-19) infection, termed Post-Acute Sequelae of COVID-19 (PASC). The typical manifestations...

Abstract Post-acute sequelae of COVID-19 (PASC) is a complex and multifaceted clinical challenge requiring to emphasize its underlying pathophysiological mechanisms. This study assessed hundreds of virological, serological, immunological, and tissue damage biomarkers in two patient cohorts who...

The neuroimmune connectome in health and disease Wheeler, Michael A.; Quintana, Francisco J. The nervous and immune systems have complementary roles in the adaptation of organisms to environmental changes. However, the mechanisms that mediate crosstalk between the nervous and immune systems...